The protective effects of Achillea L. species native in Turkey against H2O2-induced oxidative damage in human erythrocytes and leucocytes

Konyalιoğlu, Sibel; Karamenderes, Canan

doi:10.1016/j.jep.2005.06.018

Cited by 91 publications

(71 citation statements)

References 25 publications

(17 reference statements)

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“…Antinociceptive and anti-inflammatory [31], human erythrocyte and leukocyte protective [32], antispasmodic [33], antimicrobial [34] and antioxidant activities [30,35,36] of different Achillea species growing in Turkey were previously reported. A. latiloba extracts in acetone, ethyl acetate, ethanol, methanol and dimethyl sulfoxide (DMSO) affected bacteria and fungal growth because they probably contain tannins, essential oils, flavonoids and organic acids or other similar substances.…”

Section: Resultsmentioning

confidence: 91%

Screening of various solvents and extracts of Achillea latiloba Ledeb. ex Nordm for antibacterial and antifungal activities

Ertürk

2014

Herba Polonica

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S u m m a r yIn this study the antibacterial and antifungal activities of extracted Achillea latiloba Ledeb. ex Nordm (Asteraceae) samples in acetone, ethyl acetate, ethanol, methanol and dimethyl sulfoxide (DMSO) from Trabzon Province (Turkey) were investigated. Antimicrobial activity of A. latiloba varied depending on the extract of samples, dosage of extracts, and the extraction solvents for all test microorganisms. Staphylococcus aureus, Streptococcus salivarius, Klebsiella pneumoniae, Escherichia coli, Salmonella enteritidis, Streptococcus pneumoniae, Bacillus cereus, Listeria monocytogenes, Streptococcus mutans, Pseudomonas aeruginosa, Bacillus licheniformis, Micrococcus luteus, Bacillus subtillis, Proteus vulgaris andCandida albicans were studied with use of disc diffusion and agar dilution method. The results indicated that each of the crude extracts of Achillea latiloba exhibited a more or less pronounced antibacterial and antifungal potency both in Gram-positive and Gram-negative bacteria and fungi. While in the Gram-negative group, the most sensitive microorganism to Achillea latiloba were S. enteritidis and Streptococcus mutans which is Gram-positive. In the Gram-positive group, the microorganisms most sensitive to Achillea latiloba were Streptococcus mutans and L. monocytogenes. However, the least sensitive microorganism was P. vulgaris. The results presented in this paper suggest that Achillea latiloba possesses additional antimicrobial activities that has an effect against some Gram-negative, Grampositive bacteria and fungi.

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Section: Resultsmentioning

confidence: 91%

Screening of various solvents and extracts of Achillea latiloba Ledeb. ex Nordm for antibacterial and antifungal activities

Ertürk

2014

Herba Polonica

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“…Some plants and fruits have been shown to be rich sources of antioxidants. Antioxidants are involved in health maintenance and in retarding or reversing the processes of chronic degenerative diseases (21). Among dietary components, grapes, a good source of antioxidants, form the basis of discussions for the explanation of the phenomenon known as the 'French Paradox' (22).…”

Section: Discussionmentioning

confidence: 99%

Protective roles of Cimin grape tissues on oxidative stress markers in the cellular system model

Uydu¹,

Ekinci²,

Atak³

et al. 2014

Turk J Med Sci

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“…Total flavonoid (0.14%) and total phenol contents (119.4 mg=L) were also determined by using the aluminum-chloride method and modified colorimetric method using the Folin-Ciocalteu reagent, respectively (Konyalıoglu & Karamenderes, 2004). Recently, infusion of ANN was studied for its protective effect against H 2 O 2 -induced oxidative damage in human erythrocytes and leukocytes, and it was found that they show evidence of a significant antioxidant activity (Konyalıoglu & Karamenderes, 2005). The role of oxygen-derived free radicals, such as OH radical and superoxide radical, in the inflammatory process is well-known (Fantone & Ward, 1982).…”

Section: Discussionmentioning

confidence: 99%

“…Infusions prepared from ANN had antioxidant capacity, which was consistent with their total flavonoid and phenol contents (Konyalıoglu & Karamenderes, 2004). The protective effect of ANN against H 2 O 2 -induced oxidative damage in human erythrocytes and leukocytes was also examined (Konyalıoglu & Karamenderes, 2005). The aim of the current study was to investigate for the first time the antinociceptive and anti-inflammatory activities and acute toxicity of the ethanol extract of ANN in mice and rats.…”

Section: Introductionmentioning

confidence: 99%

Antinociceptive and Anti-inflammatory Activities and Acute Toxicity ofAchillea nobilis. subsp.neilreichii. Extract in Mice and Rats

Karabay-Yavasoglu¹,

Karamenderes

Baykan

et al. 2007

Pharmaceutical Biology

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The ethanol extract of Achillea nobilis L. subsp. neilreichii (Kerner) Formanék (Asteraceae) flower heads was investigated for its antinociceptive and anti-inflammatory activities and for acute toxicity in mice and rats. While the extract exhibited an antinociceptive effect during the late phase of the formalin test (100, 200, and 400 mg=kg, i.p.) and an anti-inflammatory effect in the paw edema test (100 and 200 mg=kg, i.p.), it did not exert any significant antinociceptive effect in the tail-flick test. Furthermore, administration of 400 mg=kg extract increased the latency to hot-plate test at 60 and 90 min. No significant change was detected in sensory motor performance. The acute LC 50 value of the extract was 4456 mg=kg (i.p.) in mice. The current results demonstrate that an ethanol extract of A. nobilis L. subsp. neilreichii exerts anti-inflammatory activity.

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The protective effects of Achillea L. species native in Turkey against H2O2-induced oxidative damage in human erythrocytes and leucocytes

Cited by 91 publications

References 25 publications

Screening of various solvents and extracts of Achillea latiloba Ledeb. ex Nordm for antibacterial and antifungal activities

Screening of various solvents and extracts of Achillea latiloba Ledeb. ex Nordm for antibacterial and antifungal activities

Protective roles of Cimin grape tissues on oxidative stress markers in the cellular system model

Antinociceptive and Anti-inflammatory Activities and Acute Toxicity ofAchillea nobilis. subsp.neilreichii. Extract in Mice and Rats

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