The proportion of upper gastrointestinal symptoms in the community associated with helicobacter pylori, lifestyle factors, and nonsteroidal anti-inflammatory drugs

Martin, Paul; Forman, David; Braunholtz, David; Feltbower, Richard; Crocombe, Will; Liptrott, Margaret; Axon, A. T. R.

doi:10.1016/s0002-9270(00)00918-7

Cited by 50 publications

(79 citation statements)

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“…That was in contrast to one finding which indicated a harmful effect of smoking [56]. In this study coffee or tea intake has not been shown to be related to the presence of Dyspepsia similarly studied in rural Asia [57].…”

Section: Discussioncontrasting

confidence: 96%

Dyspepsia and Associated Risk Factors at Yirga Cheffe Primary Hospital, Southern Ethiopia

Ayele¹,

Molla²

2017

Clin Microbiol

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Dyspepsia is a common symptom of gastrointestinal disease with global distribution. The prevalence of this disorder varies between 3% and 40%. Dyspeptic symptoms account 10% of hospital admissions in Ethiopia. The aim of this study was to determine the contributing factors for dyspepsia at Yirga cheffe primary hospital, Southern Ethiopia.: A case control study design was conducted between July 6, 2016 and August 10, 2016 on a total of 168 patients at Yirga cheffe primary hospital, South Ethiopia. The Helicobacter pylori (H. pylori) stool antigen test was used to analyze the stool samples and a face to face interview was taken to assess other contributing factors for the infection. Ethical clearance and informed consents was obtained before data collection. Logistic regression analysis was used to estimate odds ratio (adjusted with 95% confidence interval) of positive responses to the different risk factors. Comparisons between groups were assessed with chi-square test and a P-value of <0.05 was considered statistically significant. Helicobacter pylori antigen was detected in 13 of the 168. Helicobacter pylori infection was six times more associated with dyspeptic patients than non-Dyspeptic individuals. Anxiety and depression was six and three times more likely associated with dyspepsia, respectively. Although dyspepsia was greater among male, and peaked in the age groups of 21-30 years old, the association was not statistically significant. Moreover, patients who consume foods containing peppercorn ("key wot") have high chance of developing Dyspepsia. Study subjects who depend on untapped drinking water sources, treating their drinking water, smoking habit, chewing khat, washing their hand with soap, and their toilet with flush tank were not significantly associated with dyspepsia (P>0.05). Thus, early diagnosis of H. pylori, psychological treatment of patients and food habit of the individuals should give attention to prevent and control Dyspepsia even though additional studies need to be conducted.

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Section: Discussioncontrasting

confidence: 96%

Dyspepsia and Associated Risk Factors at Yirga Cheffe Primary Hospital, Southern Ethiopia

Ayele¹,

Molla²

2017

Clin Microbiol

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“…We did not find any significant association between these factors and dyspepsia, but we did observe the lowest prevalence of smoking and alcohol consumption in the group with the highest prevalence of dyspepsia. �imilar findings have been reported previously (26) and have been explained by the fact that the abstinence of putative offending agents is a common recommendation for dyspeptic patients in the early stages of the development of dyspepsia. The most likely explanation for our findings is therefore that lifestyle modifications introduced in the past in order to alleviate dyspeptic symptoms were the cause of our findings.…”

Section: Discussionsupporting

confidence: 81%

Prevalence and characteristics of functional dyspepsia among workers exposed to cement dust

Coppeta¹,

Pietroiusti²,

Magrini³

et al. 2008

Scand J Work Environ Health

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“…Although 5% of the cases of dyspepsia in the community are attributable to infection with H. pylori, 53 the effect of eradication therapy on the symptoms of functional dyspepsia is modest. In a meta-analysis of 17 randomized trials, In the presence of a background genetic disposition, a type 2 helper T (Th2)-cell response may be activated in the duodenum, possibly by allergens or pathogens, which cross through the gut epithelium.…”

Section: H Pylori Eradication Therapymentioning

confidence: 99%

Functional Dyspepsia

2015

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The proportion of upper gastrointestinal symptoms in the community associated with helicobacter pylori, lifestyle factors, and nonsteroidal anti-inflammatory drugs

Abstract: H. pylori is significantly associated with dyspepsia and may be responsible for 5% of upper gastrointestinal symptoms in the community.

Cited by 50 publications

References 0 publications

Dyspepsia and Associated Risk Factors at Yirga Cheffe Primary Hospital, Southern Ethiopia

Dyspepsia and Associated Risk Factors at Yirga Cheffe Primary Hospital, Southern Ethiopia

Prevalence and characteristics of functional dyspepsia among workers exposed to cement dust

Functional Dyspepsia

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