The proportion of individuals with obesity-induced hypertension among total hypertensives in a general Japanese population: NIPPON DATA80, 90

Abstract

The increased prevalence of obesity in Japan may contribute to the high prevalence of hypertension in Japan. In the present study, we calculated the odds ratio for hypertension in obesity (body mass index (BMI) >or= 25.0 kg/m(2)) using data from independent nationwide surveys conducted in 1980 and 1990. We estimated the percentage of hypertensives whose condition was due to obesity among total hypertensives in the general Japanese population. In the 1980 survey, 18.8% of 4,623 male participants were obese and 50.4% were hypertensive, whereas 22.6% of 5,893 female participants were obese and 41.1% were hypertensive. For both sexes, obese participants had a higher odds ratio for hypertension than non-obese participants (BMI < 25.0 kg/m(2)), and there was a significant dose-response relationship between BMI and the odds ratio for hypertension. Among all hypertensives, the percentage whose hypertension was due to obesity in 1980 and 1990 was 11.4% (95% confidence interval (CI): 4.7-17.7%) and 15.3% (95% CI: 6.8-23.1%) for men and 19.3% (95% CI: 12.1-25.9%) and 22.3% (95% CI: 14.6-29.3%) for women, respectively. Approximately 80-90% of individuals with obesity-induced hypertension were in the 25.0 <or= BMI < 30.0 kg/m(2) category for both sexes in each year. In conclusion, we found that obesity-induced hypertension as a proportion of total hypertension increased between 1980 and 1990 for both sexes. Obesity now is playing a more important role in the high prevalence of hypertension in Japan than it was before.

Incidence of Hypertension in Individuals with Abdominal Obesity in a Rural Japanese Population: The Tanno and Sobetsu Study

“…It is well known that obesity is significantly related to HT, and many reports show relationships between BP levels and (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12). We also have reported a strong correlation between obesity assessed by BMI and the development of HT according to our cohort data (13), as well as a correlation between ultrasound-assessed visceral fat accumulation and BP levels (14).…”

Efficacy and Safety of the Losartan-Hydrochlorothiazide Combination Tablet in Patients with Hypertension Uncontrolled by Angiotensin II Receptor Antagonist Therapy: The Aichi Research on Combination Therapy for Hypertension (ARCH) Study

“…Only alcohol consumption has a significant negative effect on changes in both systolic and diastolic BP. A long period of alcohol intake increases BP (14). In addition, previous reports have indicated that the less alcohol a patient drinks, the lower his or her BP tends to be (15).…”

Type 2 Diabetes in Well-Controlled Hypertension

“…Analysis of NIPPON DATA 80 and 90 baseline data, corresponding to the Third and Fourth National Survey on Circulatory Disorders, Japan in 1980 and 1990, respectively, revealed that the proportion of hypertension that is attributed to overweight/obesity (BMI ≥25 kg/m 2 ) has increased from 11.4% to 15.3% in men and from 19.7% to 22.2% in women. 7 Our belief is that weight management in hypertensive subjects is an important measure for primary prevention of CVD through its effects on diabetes risk, BP and other CVD risk factors. However, we note that in today's Japan there is a sizeable proportion of individuals who present with both hypertension and DM (constellation of metabolic syndrome components) without being overweight/ obese.…”