The proportion and trend of human immunodeficiency virus infections associated with men who have sex with men from <scp>C</scp>hinese voluntary blood donors: a systematic review and meta‐analysis

Lü, Jinxin; Xu, Junjie; Reilly, Kathleen H.; Li, Yongze; Zhang, Christiana Meng; Jiang, Yongjun; Geng, Wenqing; Wang, Lunan

doi:10.1111/trf.12871

Cited by 11 publications

(11 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…HIV prevalence was stable in the first two populations, but it increased from 1.77% in 2000 to 5.98% in 2010 in MSM [ 16 ], and even higher prevalence was found in MSM in Eastern China (11.3%) [ 17 ] and in Tianjin city (12.4%) which was only 137 km from Beijing [ 18 ]. MSM sought free HIV testing through blood donation screening [ 19 ], or they also might seek HIV testing in our hospital. So, we presumed that the high HIV prevalence in 21–30-year-old men was highly associated with MSM.…”

Section: Discussionmentioning

confidence: 99%

Seroprevalence of the Hepatitis B, Hepatitis C, and Human Immunodeficiency Viruses and Treponema pallidum at the Beijing General Hospital from 2010 to 2014: A Cross-Sectional Study

Wang

Zhang

et al. 2015

PLoS ONE

View full text Add to dashboard Cite

BackgroundThe hepatitis B, hepatitis C, human immunodeficiency viruses and Treponema pallidum are important causes of infectious diseases concern to public health.MethodsBetween 2010 and 2014, we used an automated chemiluminescence microparticle immunoassay to detect the hepatitis B, hepatitis C, and human immunodeficiency viruses as well as Treponema pallidum (the rapid plasma regain test was used in 2010–2011). Positive human immunodeficiency virus tests were confirmed via western blotting.ResultsAmong 416,130 subjects, the seroprevalences for hepatitis B virus, hepatitis C virus, human immunodeficiency virus, and Treponema pallidum were 5.72%, 1.23%, 0.196%, and 0.76%, respectively. Among 671 patients with positive human immunodeficiency virus results, 392 cases were confirmed via western blotting. Hepatitis B and human immunodeficiency virus infections were more frequent in men (7.78% and 0.26%, respectively) than in women (4.45% and 0.021%, respectively). The hepatitis B and C virus seroprevalences decreased from 6.21% and 1.58%, respectively, in 2010, to 5.37% and 0.988%, respectively, in 2014. The human immunodeficiency virus seroprevalence increased from 0.04% in 2010 to 0.17% in 2014, and was elevated in the Infectious Disease (2.65%), Emergency (1.71%), and Dermatology and Sexually Transmitted Diseases (1.12%) departments. The specificity of the human immunodeficiency virus screening was 71.4%. The false positive rates for the Treponema pallidum screening tests increased in patients who were 60–70 years old. The co-infection rates for the hepatitis C and human immunodeficiency viruses were 0.47% in hepatitis C virus-positive patients and 7.33% in human immunodeficiency virus-positive patients.ConclusionsDuring 2010–2014, hepatitis B virus and human immunodeficiency virus infections were more frequent among men at our institution. Although the seroprevalences of hepatitis B and C viruses decreased, the seroprevalence of human immunodeficiency virus infection increased (with higher seroprevalences in high-risk departments). Older patients were more likely to exhibit false positive findings for syphilis.

show abstract

Section: Discussionmentioning

confidence: 99%

Seroprevalence of the Hepatitis B, Hepatitis C, and Human Immunodeficiency Viruses and Treponema pallidum at the Beijing General Hospital from 2010 to 2014: A Cross-Sectional Study

Wang

Zhang

et al. 2015

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…The seeming lack of test seeking in the Netherlands may be due to the adequacy of current donor selection procedures and the availability of testing through regular public healthcare facilities in our country. It would be very interesting to apply this method to data from other regions, where donor screening may be less adequate .…”

Section: Discussionmentioning

confidence: 99%

“…Rather than out of purely altruistic reasons, some individuals may be driven to donate in order to have their infection status determined . As this motivation would be strongest following risk behaviour for acquiring infection, test‐seeking behaviour poses a threat for blood transfusion safety .…”

Section: Introductionmentioning

confidence: 99%

A novel approach to detect test‐seeking behaviour in the blood donor population: making the invisible visible

et al. 2016

View full text Add to dashboard Cite

show abstract

“…High‐risk individuals may underestimate or may not understand their risk and do not feel the need for infectious disease testing at VCTs, or they are aware of their risk and actively seek testing at blood banks . In the latter case, high‐risk donors knowingly use blood centers as HIV testing sites . In the former case, donors also end up using blood centers as HIV testing sites but may be doing so unintentionally .…”

Section: Discussionmentioning

confidence: 99%

Self‐reported historic human immunodeficiency virus (HIV) testing in a Brazilian blood donor HIV case‐control study

et al. 2016

View full text Add to dashboard Cite

BACKGROUND There has been increased worldwide emphasis on the many benefits of HIV serostatus awareness for both infection prevention and improved treatment outcomes. Previous studies indicate that donors may use blood donation to be tested; the objectives of this analysis were to assess, among donors with previously undisclosed risk behavior in the 12 months before donation, the frequency of those who have previously been HIV tested and the demographic and behavioral factors associated with such testing. STUDY DESIGN AND METHODS In this secondary analysis from an HIV case-control study of blood donors in Brazil, we analyzed the response to the question: “Other than blood donation, have you ever been tested for HIV?” Demographic and disclosed risk behaviors associated with previous testing were determined. RESULTS The study included 341 HIV-positive cases and 791 HIV-negative controls (1:2 case/control ratio). Overall, 31% of blood donors (40% of cases and 26% of controls) reported having been tested for HIV outside of blood donation. History of HIV testing varied according to gender, HIV status, and reported sexual risk behavior. CONCLUSION While it is encouraging that previous testing was more frequent in donors with acknowledged sexual risk behavior in Brazil, 60% still had not been tested for HIV outside of the blood donation setting. Educating donors on the importance of not using blood centers as a means to get HIV tested in Brazil, especially if they engage in higher risk behaviors but rather seek alternate testing venues, could improve the safety of donated blood.

show abstract

The proportion and trend of human immunodeficiency virus infections associated with men who have sex with men from Chinese voluntary blood donors: a systematic review and meta‐analysis

Cited by 11 publications

References 29 publications

Seroprevalence of the Hepatitis B, Hepatitis C, and Human Immunodeficiency Viruses and Treponema pallidum at the Beijing General Hospital from 2010 to 2014: A Cross-Sectional Study

Seroprevalence of the Hepatitis B, Hepatitis C, and Human Immunodeficiency Viruses and Treponema pallidum at the Beijing General Hospital from 2010 to 2014: A Cross-Sectional Study

A novel approach to detect test‐seeking behaviour in the blood donor population: making the invisible visible

Self‐reported historic human immunodeficiency virus (HIV) testing in a Brazilian blood donor HIV case‐control study

Contact Info

Product

Resources

About