1973
DOI: 10.1002/bit.260150318
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The properties of magnetic supports in relation to immobilized enzyme reactors

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Cited by 216 publications
(55 citation statements)
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“…Magnetic carrier technology (MCT), first reported by Robinson et al in 1973 [1], has become an increasingly popular tool in bioseparations, environmental and material science [2][3][4][5]. A distinct advantage of this technology is that magnetic materials can be readily isolated from sample solutions by the application of an external magnetic field.…”
Section: Introductionmentioning
confidence: 99%
“…Magnetic carrier technology (MCT), first reported by Robinson et al in 1973 [1], has become an increasingly popular tool in bioseparations, environmental and material science [2][3][4][5]. A distinct advantage of this technology is that magnetic materials can be readily isolated from sample solutions by the application of an external magnetic field.…”
Section: Introductionmentioning
confidence: 99%
“…[19][20][21] In the same period, the immobilization of enzymes (as for example, lipase) in magnetic materials has become an interesting approach for the recovery and separation of biocatalysts. 22 Magnetic affinity chromatography also received attention as a separation technique in biotechnology. 20 Magnetic separation using superparamagnetic nanoparticles and hybrid magnetic nanomaterials with organic or inorganic coatings, that can be modified with specific recognition groups, was first applied for cell sorting and separation of biologically active components, but later received attention in other fields of application, such as for heavy metal recovery [23][24][25] and catalyst separation.…”
Section: Magnetic Separation: From Biotechnology To Catalysismentioning
confidence: 99%
“…The use of magnetic iron oxide in polymer matrices (magnetic nano-and microencapsulation) to impart a magnetic moment to the particles began in the 1970s in the field of biotechnology. Most of these studies focused on enzyme immobilization and isolation of a wide range of specific cell binding agents (Robinson et al 1973, Kronick et al 1978, Olsvik et al 1994, Thomas and Landsdorp 1994, Van der Wolf et al 1994, hyperthermia (Chen et al 1992, Jordan et al 1997, Shinkai et al 1999, magnetic resonance imaging contrast enhancement (Weissleder et al 1995, Jung and Jacobs 1995, Bulte et al 1999, tissue specific release of therapeutic agents (Gupta and Hung 1994, Lübbe et al 1996a, Kumar 2000, radioimmunoassay (Nye et al 1976), and magnetic targeting of therapeutic radio isotopes (Hafeli et al 1994).…”
Section: A Brief History Of Magnetic Particle Targetingmentioning
confidence: 99%