The prognostic value of left atrial dyssynchrony measured by speckle tracking echocardiography in the general population

Karsum, Emil Høegholm; Andersen, Ditte Madsen; Modin, Daniel; Biering-Sørensen, Sofie; Møgelvang, Rasmus; Jensen, Gorm; Schnohr, Peter; Gislason, Gunnar

doi:10.1007/s10554-020-02154-3

Cited by 2 publications

(2 citation statements)

References 30 publications

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“…Another recent article using 3D speckle-tracking correlates these electro-anatomical concepts, dyssynchrony and delay in atrial conduction in patients with PAF, verifying dyssynchrony in the early stages of atrial remodeling 20 . Values among the normal population recorded a mean of 42 ms and 2% relative to the RR intervals with negative prognostic implications in terms of the greater risk of global mortality, atrial fibrillation and stroke mostly in females 21 . In summary, changes in the sequence of electro-anatomical-physiological mechanical activation can be suspected with techniques based on the left atrial strain and can occur anywhere in the left atrium facilitating the re-entry and appearance of repetitive forms 22 .…”

Section: Discussionmentioning

confidence: 99%

Assessment of short forms of recurrent atrial extra systoles by echocardiography with left atrial strain in ambulatory patients without organic cardiopathy

Soler¹,

García-Parés²,

Valero³

et al. 2023

ACM

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Aim: To analyse the potential usefulness and clinical relevance of the assessment by echocardiography with left atrial strain, based on the myocardial atrial deformation curves with speckle-tracking velocity vector imaging (VVI), in the analysis of shortform recurrent atrial extra systoles in ambulatory patients not suffering from organic cardiopathy. Methods: We designed a descriptive, prospective, and observational study including 270 patients between the ages of 18 and 75 assessed during an outpatient cardiology consultation attended due to palpitations over a period of two years. Using ambulatory electrocardiographic monitoring, we selected cases with short forms of repetitive atrial extrasystole, isolated or recurrentatrial fibrillation and a control group formed by those patients without repetitive ectopia. All patients underwent a thorough echocardiographic study during their first cardiological visit. Results: The analysis of the dynamic curves segmental deformation generated after an atrial extrasystole can reveal different points of origin of the extrasystole and detect specific anatomical alterations in the interatrial conduction at the level of the Bachmann's fascicle showing different models of electro anatomical activation possibly involved in the appearance of repetitive forms. Higher values of dyssynchrony between the septal and lateral wall and elongation in the time of interatrial electromechanical conduction could also be related to the existence of repetitive ectopic beats. Conclusions: Our ambulatory study employing the left atrial longitudinal strain, particularly in its segmental analysis, provides new insights into its the usefulness and potential clinical relevance.

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Section: Discussionmentioning

confidence: 99%

Assessment of short forms of recurrent atrial extra systoles by echocardiography with left atrial strain in ambulatory patients without organic cardiopathy

Soler¹,

García-Parés²,

Valero³

et al. 2023

ACM

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“…15 In addition, the LA strain has demonstrated prognostic utility in the general population. 16,17 There is a paucity of information on LA strains in pregnancy and preeclampsia. It is not evident whether LA strain is impaired even in the absence of extensive remodeling, hypertension or both, in women after preeclampsia.…”

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confidence: 99%

Left Atrial Mechanics Following Preeclamptic Pregnancy

O’Driscoll,

McCarthy,

Giorgione

et al. 2024

Hypertension

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BACKGROUND: Preterm preeclampsia is a pregnancy complication associated with myocardial dysfunction and premature cardiovascular disease morbidity and mortality. Left atrial (LA) strain is a noninvasive index of left ventricular end diastolic pressure and an early marker of heart failure risk. This study aimed to evaluate LA strain during the postpartum period in participants with and without preterm preeclampsia and to assess whether this varied in the presence of hypertension and/or cardiac dysfunction. METHODS: In this longitudinal cohort study, 321 women from 28 hospitals with preterm preeclampsia (cases) underwent cardiovascular assessment 6 months postpartum. This is a secondary analysis of the PHOEBE study (ISRCTN01879376). An uncomplicated pregnancy control group (n=30) was recruited from a single center for comparison. A full cross-sectional transthoracic echocardiogram was performed, and from these images, the myocardial strain of the left atrium, including reservoir, conduit, and contractile strain, as well as LA stiffness, were calculated. RESULTS: At 6 months postpartum, compared with controls, prior preeclampsia was associated with a significantly attenuated LA reservoir, conduit, and contractile strain, as well as increased LA stiffness (all P <0.001). LA strain was further reduced in preeclamptic women who had and had not developed hypertension, systolic, or diastolic dysfunction at 6 months postpartum (all P <0.05). CONCLUSIONS: LA mechanics were significantly attenuated at 6 months postpartum in participants with preterm preeclampsia, whether or not they remained hypertensive or had evidence of ventricular dysfunction. Further studies are needed to determine whether postnatal LA strain may identify women at greater risk for future cardiovascular disease.

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The prognostic value of left atrial dyssynchrony measured by speckle tracking echocardiography in the general population

Cited by 2 publications

References 30 publications

Assessment of short forms of recurrent atrial extra systoles by echocardiography with left atrial strain in ambulatory patients without organic cardiopathy

Assessment of short forms of recurrent atrial extra systoles by echocardiography with left atrial strain in ambulatory patients without organic cardiopathy

Left Atrial Mechanics Following Preeclamptic Pregnancy

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