The prognostic nutritional index and postoperative complications after curative lung cancer resection: A retrospective cohort study

Prognostic Significance of the Preoperative Controlled Nutritional Status Score in Lung Cancer Patients Undergoing Surgical Resection

“…It is not clear whether correcting hypoproteinemia can reduce postoperative complications or cancer recurrence. Further study is needed to investigate whether it can effectively improve the survival rate and reduce postoperative complications and tumor recurrence (5). Cholesterol metabolism is abnormal in malignant tumor cells, including prostate cancer, lung cancer, acute myeloid leukemia, breast cancer, and other tumors.…”

“…It has a significant relationship with prognosis in various cancers, improving both disease-free survival (DFS) and overall survival (OS). It is a potential predictor of cancer progression and postoperative complications (5). The score is based on the serum albumin concentration, the total number of peripheral lymphocytes, and the index, calculated with the total cholesterol concentration.…”

“…Furthermore, lymphopenia can lead to anti-tumor immune suppression and poor OS (11). CONUT is used as an immune nutritional status score, which can be used to enhance postoperative recovery (ERAS) or as a potential predictor of cancer progression and postoperative complications (5). In recent years, CONUT scores have been extensively studied in colorectal cancer (6), gastric cancer (12), bladder cancer (13), and breast cancer (14).…”

Rehabilitation treatment of enteral nutrition whey protein in lung cancer patients in southern China

“…At present, radical surgery can effectively remove the lesion, and it is still an effective method to treat early and middle lung cancer and prolong the survival time of patients (Lee et al, 2019;Lu et al, 2020;Shi et al, 2019). However, patients with lung cancer have poor nutrition status and weakened immune function before surgery (Park et al, 2020;Ulmann et al, 2019). At the same time, due to the stress response brought by surgery, malnutrition will be further exacerbated, which will affect the immune function of patients.…”

Commentary: Soft prognosticators following radical treatment of lung cancer: The time has come for a more integrated approach

“…The study from Park and colleagues 1 is an interesting analysis reporting on the inverse association between prognostic nutritional index (PNI) and incidence of postoperative adverse events and late mortality after curative resection for lung cancer. This contribution adds to the growing number of studies reporting an association between baseline patient-related characteristics (functional, metabolic, psychological) and cancer progression after curative lung resection.…”