The preventive effect of aqueous extract of Rosemary (<i>Rosmarinus officinalis</i>) leaves against the nephrotoxicity of carbon tetrachloride in mice

Hamed, Houda; Boulila, Salha; Ghrab, Ferdaws; Kallel, Rim; Boudawara, Tahia; Feki, Abdelfattah El

doi:10.1080/13813455.2018.1508236

Cited by 7 publications

(6 citation statements)

References 43 publications

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“…1.0 mL /kg body weight of 10% CCl 4 twice a week for 6 weeks) in albino rats and this effect was related to its antioxidant activity (Sakr & Lamfon, 2012). In line with the above study, Hamed and her colleagues represented that the aqueous extract of rosemary could suppress nephrotoxic effects of CCl 4 in mice through the prevention of lipid peroxidation (Hamed et al, 2020). The protective effects of rosemary and its main compounds against nephrotoxic agents have been summarized in Table 2.…”

Section: Chemical Agents Induced Toxicitymentioning

confidence: 75%

“…-improved the structural changes in the kidney -# blood urea, # Creatinine, # uric acid (Azab et al, 2014 -# LPO, # Caspase-3 activity -inhibited ROS generation -" GSH level -" SOD, " CAT, " GSH-Px, " GR, " GST activity (Sahu et al, -improvement in biochemical markers -antioxidant activity -# LPO, " GSH level (Hamed et al, 2020) Abbreviations: CA: Carnosic acid; CAT: Catalase; COX-2: Cyclooxygenases; GGT: Gamma-glutamyl transferase; GSH-Px: Glutathione peroxidase; GR: Glutathione reductase; GSH: Glutathione, GST: Glutathione S-transferases; i.p. : intraperitoneally; LPO: Lipid peroxidation; MDA: Malondialdehyde; RA: Rosmarinic acid; ROS: Reactive Oxygen Species; SOD: Superoxide dismutase; TAC: Total antioxidant capacity.…”

Section: Ethanolmentioning

confidence: 99%

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An updated review of protective effects of rosemary and its active constituents against natural and chemical toxicities

Alavi

Fanoudi

Mehri

et al. 2020

Phytotherapy Research

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Natural and chemical toxic agents cause severe adverse effects on people's health in a variety of exposing ways. Herbal medications have taken into consideration as alternative safe treatments for toxicities. Rosmarinus officinalis also known as rosemary belongs to the Lamiaceae family. Rosemary and its constituents including carnosic acid, rosmarinic acid, and carnosol have a lot of benefits such as antiinflammatory, antioxidant, anti-mutagenic, anti-bacterial, antiviral, antinociceptive, and neuroprotective activities. In this literate review, we focused on the protective effects of rosemary and its main compounds against natural and chemical toxicities in both in vitro and in vivo studies. The protective effects of rosemary and its components are mostly mediated through different mechanisms such as the inhibition of oxidative stress, reduction of inflammatory mediators including tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), interleukin-17 (IL-17), cyclooxygenase-2 (COX-2) and nuclear factor ĸB (NF-ĸB) as well as the modulation of apoptosis and mitogen-activated protein kinase (MAPK) signaling pathways.

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Section: Chemical Agents Induced Toxicitymentioning

confidence: 75%

Section: Ethanolmentioning

confidence: 99%

An updated review of protective effects of rosemary and its active constituents against natural and chemical toxicities

Alavi

Fanoudi

Mehri

et al. 2020

Phytotherapy Research

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“…Pretreatment with R. officinalis leaf extract attenuated CCl 4 -related toxic effects. 44 The polyphenolic profile of Tunisian R. officinalis leaf extract is characterized by its richness in carnosic and rosmarinic acids. 138 The potent nephroprotective effects of carnosic 139 and rosmarinic 140 acids were observed in cisplatininduced nephrotoxicity in rats.…”

Section: Rosmarinus Officinalismentioning

confidence: 99%

“…Olea europea35 Ceratonia siliqua18 ; Lycium europaeum 27 ; Mentha peperita 31 ; Rosmarinus officinalis44 ; Teucrium polium46 ; Trigonella foenum-graecum48 Tunisian nephroprotective plants J Explor Res Pharmacol plant mainly contains syringic acid, myricetin glycosides, and gallic acid derivatives.…”

mentioning

confidence: 99%

Tunisian Nephroprotective Plants: A Review

Wannes¹,

Tounsi²

2022

J Explor Res Pharmacol

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In Tunisian folk medicine, several herbs are prescribed for reducing renal damage and to avoid kidney related complications. These can be of immense value in combating renal damage. In this review, we provide a description of the current literature on the use of indigenous herbs as alternative medicine for treating renal damage. The aim of this review was to collect information on promising active phytoconstituents such as organosulfur compounds, polyphenols, terpenes, alkaloids phenylpropanoids, and polysaccharides from Tunisian plants that have been scientifically examined for their nephroprotective capacities. Twenty-nine Tunisian medicinal plants have been reported for their significant nephroprotective activities against renal toxicities in animal models. Lamiaceae was the most commonly used Tunisian plant family used for renal protection. The leaves were maximally used for nephroprotection compared to the other plant parts. Nephrotoxicity is commonly the result of several nephrotoxins. Many studies have focussed on drug-caused renal failure which is one of the major problems in medical practice. Other studies focused on other important nephrotoxicity factors, including drugs and industrial chemicals. This literature review highlights the use of some medicinal plants as nephroprotective agents. To defend against this nephrotoxicity, some medicinal plants, known as nephroprotective agents, have been highlighted in this review.

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“…A: Condimento para salsas y platos diversos, repostería, mezclas de especias, saborizante de aperitivos. Antioxidante, antimicrobiano, antidiabético, antiinflamatorio, anti-dispepsia, desórdenes gastrointestinales, relajante muscular, analgésico, anti-artritis, anticáncer, antialérgico, hipotensor, anticoagulante, antiasmático, hepatoprotector, hipolipidémico, hipocolesterolémico, anti-aterosclerosis, potenciador de la memoria, neuroprotector: Parkinson, Alzheimer, antidepresivo [Hassani et al, 2016;Andrade et al, 2018;Borges et al 2019], anti-osteoporosis (Elbahnasawy et al, 2109), nefroprotector (Hamed et al, 2018 Antioxidante, cardioprotector, hipotensor, anticoagulante, antianémico, anticáncer, anti-aterosclerosis, antidiabético, anti-obesidad, anti-dislipidemia, laxante, hepatoprotector, hipocolesterolémico, antiinflamatorio, analgésico, inmunoestimulante, ansiolítico, antidepresivo, antidermatósico, antialérgico, antimicrobiano, antiviral, repelente de insectos, antinefrítico, anti-edad, adaptógeno [Ulbricht et al, 2009;Hurrell et al, , 2015bArenas et al, 2015;Valdivia-López & Tecante, 2015;Ullah et al, 2016]. A: Condimento para salsas y platos diversos, mezclas de especias, repostería, saborizante de infusiones y aperitivos.…”

Section: Leonurus Japonicusunclassified

Lamiaceae medicinales y aromáticas comercializadas en el Área Metropolitana de Buenos Aires, Argentina

2020

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Esta contribución, enmarcada en la etnobotánica urbana, presenta 21 especies de Lamiaceae cuyos productos se comercializan como medicinales y aromáticos (condimenticios y saborizantes) en el Área Metropolitana de Buenos Aires, Argentina. Se relevaron 200 sitios de expendio del circuito comercial general (dietéticas) y 5 supermercados del circuito comercial restringido del segmento de inmigrantes chinos. En los sitios de venta se adquirieron muestras de referencia de productos de las distintas especies. Se entrevistaron 410 personas acerca de los usos asignados a cada especie. Para definir estos usos se recurrió también a otras fuentes de información, entre estas, los medios masivos. El trabajo se suplementó con una revisión de los estudios académicos sobre la actividad biológica y efectos evaluados de las especies relevadas, a los fines de su correlación con los usos localmente asignados. La mayoría de las especies relevadas (87,5%) son “visibles”: se comercializan en el circuito comercial general, lo cual evidencia el nivel elevado de conocimiento botánico local sobre las Lamiaceae. Asimismo, la presencia de las plantas y productos incrementa la diversidad biocultural local, es decir, tanto la diversidad de especies (dimensión biológica) como de sus conocimientos asociados (dimensión cultural).

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The preventive effect of aqueous extract of Rosemary (Rosmarinus officinalis) leaves against the nephrotoxicity of carbon tetrachloride in mice

Cited by 7 publications

References 43 publications

An updated review of protective effects of rosemary and its active constituents against natural and chemical toxicities

An updated review of protective effects of rosemary and its active constituents against natural and chemical toxicities

Tunisian Nephroprotective Plants: A Review

Lamiaceae medicinales y aromáticas comercializadas en el Área Metropolitana de Buenos Aires, Argentina

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