The prevention of anaemia in pregnancy in primigravidae in the guinea savanna of Nigeria

The impact of malarial infection and diet on the anaemia status of rural pregnant Malawian women

“…Its aetiology is complex, and has been attributed to a variety of factors including malaria and helminth infections (for example hookworm) as well as dietary de®ciencies of iron and folate. Folate de®ciency secondary to malaria and the genetic disorder sickle cell anaemia may also be important (Fleming, 1982(Fleming, , 1989a(Fleming, , 1989bFleming et al, 1986). In this Malawian study, the results presented in Tables 8 and 9 demonstrate that two of these factors, existence of asymptomatic malarial parasitaemia on the test day, and the diet, had a signi®cant impact on the haematological and biochemical iron indices measured.…”

“…There are several reports of folate de®ciency secondary to malaria (Fleming et al, 1986), reportedly induced by malarial haemolysis which thus stimulates erythropoiesis and increases folate requirements (Strickland & Kostinas, 1970). Women may be especially susceptible to folate de®ciency during pregnancy when folate requirements are already very high.…”

Appraisal of the Efficacy of Sp-Iptp at Aminu Kano Teaching Hospital-Impact on Maternal Anaemia, Malaria Parasitaemia and Clinical Malaria

“…Only primigravidae were recruited for uniformity, because susceptibilty to malaria in pregnancy varies among the parity groups [14,16,17].…”

“…In many countries in sub-Saharan Africa, SP-IPTp have proven efficacious in reducing the burden of pregnancy associated malaria, and two doses of SP were found to be enough to significantly reduce the prevalence of peripheral and placental malaria parasitaemia, but its effectiveness is being threatened by increasing levels of parasite resistance to SP across Africa and South East Asia [14][15][16][17][18][19]. This may seriously undermine the benefits of national SP-IPTp programs in these regions [16].…”

Regular vitamin C supplementation during pregnancy reduces hospitalization: outcomes of a Ugandan rural cohort study

“…It is estimated that 33 to 75% of women in developing countries are affected by anemia in pregnancy and its predisposing factors include multi-parity, low socio-economic status, malaria infestation, HIV infection and others [20][21]. Coming to RTI, it is often due to poor housing and clothing also low socio-economic status, poor immune system, malnutrition, close contacts with children under age 3 and "last but not least" improper antibiotic use [19].…”