Regular vitamin C supplementation during pregnancy reduces hospitalization: outcomes of a Ugandan rural cohort study

Unim, H.; Edward, Byamukama

doi:10.4314/pamj.v5i1.56178

Cited by 10 publications

(3 citation statements)

References 20 publications

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“…A higher quality diet during pregnancy was associated with lower diastolic blood pressure ( 34 ). Consumption of vitamin C supplements in a group of 384 pregnant women reduces the hospitalisation time even if there is no access to fruit and vegetables ( 37 ). Changamir et al conducted a study on 8468 pregnant women in 2015 and found that women who took multivitamins during pregnancy had better gestational weights, which is a significant predictor of birth weight ( 38 ).…”

Section: Discussionmentioning

confidence: 99%

Association between the Dietary Inflammatory Index and the Risk of Cesarean Delivery

Sheikholmolooki,

Djazayery,

Abbasi

2024

ijph

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Background: Cesarean section (CS) is one of the most important pregnancy concerns in the world. Increased inflammation is associated with increased risk factors for cesarean section. Diet plays a major role in reducing inflammation. This study aimed to investigate the relationship between dietary inflammatory index (DII) and the risk of Cesarean section in Tehranian women. Methods: This case-control study included 390 pregnant women in Tehran, Iran between 2020 and 2021 at their initial visit to pregnancy clinics, selected by a cluster sampling method. Dietary intakes were determined using valid reliable questionnaires and DII was calculated. Weight, height, and waist circumference were also measured. Results: The mean age of the subjects was 28.5 yr (± 5.02) and weight, body mass index (BMI) and waist circumference (WC) in the case group with a higher DII were higher. Odds ratio (OR) of cesarean section in DII quartiles was statistically significant. Confounding factors including age, BMI and total energy intake were adjusted in the first model and weight, waist circumference, physical activity and supplements in the second model and the relationship remained significant (P<0.001). Conclusion: High scores of dietary inflammatory index, possibly through an increase in inflammatory factors, can increase the chances of having a cesarean section.

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Section: Discussionmentioning

confidence: 99%

Association between the Dietary Inflammatory Index and the Risk of Cesarean Delivery

Sheikholmolooki,

Djazayery,

Abbasi

2024

ijph

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“…The available information is based on animal data, some clinical studies and observations in adult patients. For example, maternal ascorbic acid overdosage can increase the risk of hyperoxaluria 28 . High dosing can also lead to nausea, abdominal pain and other gastrointestinal problems.…”

Section: Characteristics Of Ascorbic Acid Intake During Pregnancymentioning

confidence: 99%

Ascorbic acid intake during pregnancy

Podolska,

Mazankova,

Goboova

et al. 2023

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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The continuing global increase in allergic conditions and diseases in children is now a serious public health and scientific issue. Amongst other concerns is the maternal antenatal diet as intake of essential nutrients. Even small deficits in essential vitamin C can permanently impair the developing brain for example. In this article, we first review ascorbic acid deficiency in different organs of both mother and foetus. However, major emphasis is on the importance of vitamin C in foetal immunity with studies showing an inverse relationship between maternal intake of fresh fruit and vegetables and allergic conditions in childhood, inter alia. Other review results are included.

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“…Vitamin C, on the contrary, has potent antioxidant activity in hydrophilic environments, acting as a scavenger of reactive oxygen and nitrogen species. In addition, vitamin C plays a significant role in the regeneration of oxidized vitamin E (14).…”

Section: ' Introductionmentioning

confidence: 99%

Association between antioxidant vitamins and oxidative stress among patients with a complete hydatidiform mole

Ferraz

Ramos

Braga

et al. 2020

Clinics

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This study aimed to evaluate the potential relationship between oxidative stress, dietary intake, and serum levels of antioxidants in patients with a complete hydatidiform mole (CHM) compared with controls. METHODS: This was an observational cross-sectional study conducted in Rio de Janeiro, Brazil. A total of 140 women were enrolled in this study and divided into four groups: 43 patients with CHM, 33 women who had had an abortion, 32 healthy pregnant women, and 32 healthy non-pregnant women. All participants underwent blood sampling, assessment using a semiquantitative food frequency questionnaire, and anthropometric measurement. Blood samples were collected after overnight fasting (10-12 h). Vitamin levels (A, C, and E) were determined by ultra-performance liquid chromatography, and gamma-glutamyl transferase levels were assessed using an automated quantitative analysis system (Dimension s , Siemens). RESULTS: Although all groups showed sufficient serum vitamin A and E levels, the participants had inadequate dietary intake of these vitamins. Conversely, all groups had an insufficient serum level of vitamin C, despite adequate intake. The gamma-glutamyl transferase values did not differ significantly among the groups. However, elevated serum levels of this enzyme were observed in several patients. CONCLUSIONS: All groups exhibited high levels of oxidative stress, as evaluated by gamma-glutamyl transferase levels, and had inadequate intake of antioxidant vitamins. Therefore, the high exposure to oxidative stress found in our study, even in healthy pregnant and non-pregnant women, may increase the incidence of CHM in this region.

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Regular vitamin C supplementation during pregnancy reduces hospitalization: outcomes of a Ugandan rural cohort study

Abstract: BACKGROUND: Vitamin C or ascorbic acid is a hydro-soluble lactone (synthesized from glucose) essential to human

Cited by 10 publications

References 20 publications

Association between the Dietary Inflammatory Index and the Risk of Cesarean Delivery

Association between the Dietary Inflammatory Index and the Risk of Cesarean Delivery

Ascorbic acid intake during pregnancy

Association between antioxidant vitamins and oxidative stress among patients with a complete hydatidiform mole

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