The prevalence of pancreatitis in organophosphate poisonings

Sahin, Iç; Onbaşı, Kevser; Şahin, Hanım Güler; Karakaya, Cengiz; Üstün, Yusuf; Noyan, Tevfik

doi:10.1191/0960327102ht234cr

Cited by 71 publications

(64 citation statements)

References 6 publications

(9 reference statements)

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“…OP compounds are highly toxic and can be easily obtained. OP compounds are commonly preferred for suicide attempts (19,20,22,23). In our study, oral intake was the most common way of intoxication and suicide attempt was the most common cause.…”

Section: Discussionmentioning

confidence: 51%

Epidemiology of organophosphate intoxication and predictors of intermediate syndrome

Çolak¹,

Erdoğan²,

Baydın³

et al. 2014

Turk J Med Sci

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In the cotton zone of Punjab, Pakistan, only 20% of wheat is sown at the optimum sowing time, i.e. the first fortnight of November, while the remaining sowing is done from late November (30%) to December (50%) (Khan et al. 2002). Wheat has a determinate growth habit and a delay of each day in sowing from mid-November onward decreases the number of tillers, leaf area, and total dry matter. Moreover, late sowing of wheat also delays anthesis, which ultimately reduces grain yield at a rate of 30-40 kg day -1 ha -1 (Hussain et al. 1998;Akmal et al. 2011). Late-sown wheat has to complete its life cycle in a short duration because starch accumulation terminates at the same time in both normal and late-sown plants ( Khan et al. 2010). Late sowing results in poor germination and delayed emergence due to the prevalence of low temperatures at that time. In consequence, a weak crop stand and less tillering affect grain yields. Moreover, high temperatures at later growth stages enforce shortening of the grain filling period and early maturity.Limited availability of canal irrigation water and low precipitation are also common in the cotton-wheat cropping system of the South Punjab, Pakistan, and when coupled with late sowing, they severely affect wheat yields. Crop production in this region mainly depends on irrigation, but unfortunately per capita water availability is declining at an alarming rate, from 5260 m 3 in 1951 to 1066 m 3 in 2010, and it will be less than 870 m 3 per capita by 2025 (Ahmad et al. 2009). Due to scarcity in irrigation and water supply, and increasing competition for water demand from nonagricultural sectors, the focus is already shifting from maximizing the production per unit area towards the maximization of the production per unit of water consumed, often termed as water productivity (Fereres and Soriano 2007). For that purpose, and to optimize crop economic returns under conditions of less irrigation water use (irrigation supply below full crop water requirement, evapotranspiration [ETo]), new strategies should be developed. These challenges may be overcome either by minimizing the water losses or by improving the crop water use efficiency. These can be achieved by promoting a large and early canopy development of growing plants.

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Section: Discussionmentioning

confidence: 51%

Epidemiology of organophosphate intoxication and predictors of intermediate syndrome

Çolak¹,

Erdoğan²,

Baydın³

et al. 2014

Turk J Med Sci

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“…I Sahin et al 6 conducted a prospective study in the Department of Internal Medicine, University of Yuzuncu Yil, Medical faculty,Van,Turkey in 2002, to find the prevalence of pancreatitis in OP poisoning. Four of the total 47 patients with acute OP poisoning had obviously elevated Amylase and Lipase levels (Amylase> 300 U/L ; Lipase >60 U/L).…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Hyper Amylasemia and Acute Pancreatitis in Organophosphate Poisonings

Chaturvedi¹,

Dutta²,

Sarkar³

et al. 2014

IOSR-JDMS

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“…Organophosphate Poisoning from Symptoms to Diagnosis (8). Plazma ve eritrosit kolinesteraz düzeyleri tanıda yardımcıdır ve tedavide yol göstericidir, fakat her merkezde çalışılmamaktadır.…”

Section: Semptomdan Tanıya Organofosfat İntoksikasyonuunclassified

Organophosphate Poisoning from Symptoms to Diagnosis

Akkuzu

Kalkan

Karagözlü

et al. 2017

Turkish J Pediatr Dis

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oranı alınan maddenin cinsine, miktara, hastanın önceki sağlık durumuna, nakilde geçen süreye, solunum desteği, entübasyon ve ventilatörden ayrılma ile ilgili faktörlere bağlı olmakla birlikte, ortalama %3-25 arasındadır (2).Burada nöbet ve bilinç bulanıklığı ile acil servise başvuran öykü-sünde organofosfat zehirlenmesi olmasa da klinik bulgulardan şüphe edilerek tedavisi başlanan ve yatışının üçüncü gününde taburcu olan 13 yaşında kız hasta sunulmuştur. GİRİŞ ÖZZehirlenme olguları acil servislerde sıkça karşılaşılan önemli bir sağlık sorunudur. Zehirlenmelere akut süreçte müdaha-lede gecikme artmış mortalite ve morbiditeye neden olabilir. Organik fosfor bileşikleri tüm dünyada yaygın olarak tarımda, evlerde, bahçelerde, veterinerlikte ve kimyasal silah yapımında kullanılmaktadır. Yılda yaklaşık 3 milyon insan organofosfatlara maruz kalmakta ve 300 bine yakını ölmektedir. Olgumuzda daha önce bilinen hastalığı olmayan jeneralize tonik klonik nöbet geçirme sonrası acile başvuran 13 yaşında kız hasta sunulmuştur. Hastanın zehirlenme öyküsü olmamasına rağmen klinik ve laboratuvar bulgularının organofosfat intoksikasyonu özellikleri taşıması nedeniyle verilen atropin ve pralidoksim tedavilerine dramatik cevap alınmıştır. Hasta daha sonradan intihar amaçlı böcek ilacı içtiğini itiraf etmiştir. Acil servise başvurularda özellikle daha önceden sağlıklı çocuklarda abdominal kramplar, lakrimasyon ve salivasyon artışı, solunum sıkıntısı, aritmi, anksiyete, nöbet, bilinç bulanıklığı görülmesi durumunda organofosfat zehirlenmeleri akla gelmelidir.Anahtar Sözcükler: Kolinerjik semptomlar, Nöbet, Organofosfat zehirlenmesi ABSTRACTPoisoning is an important health problem that is common in emergency services. Delay in intervention in the acute process of poisoning can lead to increased mortality and morbidity. Organic phosphorus compounds are widely used in agriculture, in houses, in gardens, in veterinary medicine and in chemical weapons production all around the world. Approximately 3 million people are exposed to organophosphates per year and nearly 300 thousand die. We present a 13-year-old previously healthy girl with generalized tonic clonic seizures. Although there was no pertinent poisoning history, the diagnosis was made based on the clinical signs and the dramatic response to atropine and pralidoxime treatments. After the resolution of the symptoms, the patient confessed that she had attempted suicide with an insecticide. Emergency organophosphate intoxication should be considered especially if abdominal cramps, increased lacrimation and salivation, respiratory distress, arrhythmia, anxiety, seizure, and decreased consciousness are observed in previously healthy children.

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The prevalence of pancreatitis in organophosphate poisonings

Cited by 71 publications

References 6 publications

Epidemiology of organophosphate intoxication and predictors of intermediate syndrome

Epidemiology of organophosphate intoxication and predictors of intermediate syndrome

Prevalence of Hyper Amylasemia and Acute Pancreatitis in Organophosphate Poisonings

Organophosphate Poisoning from Symptoms to Diagnosis

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