“…The nosocomial infection is classified according to the species and the causative agent into 4 parts, including surgical site infections (SSI), urinary tract infections (UTI), bloodstream infections (BSI), and respiratory pneumonia (RP) ( Fig. 2 ) [22] , [90] , [96] . Fig.…”
Section: Resultsmentioning
confidence: 99%
“…Nosocomial infections (NIs) is defined infections that occurs in patients due to treatment procedures consequence of hospitalization in hospital or medical centers [66] , [60] , [7] , [82] . Nosocomial infections occur among patient's 48 h or more following hospital admission [66] , [22] . According to reported Center Disease Control (CDC) in the United States, 60,0000–80,0000 cases of needle stick injuries each year occur among health care worker [89] , [95] , [97] .…”
“…The nosocomial infection is classified according to the species and the causative agent into 4 parts, including surgical site infections (SSI), urinary tract infections (UTI), bloodstream infections (BSI), and respiratory pneumonia (RP) ( Fig. 2 ) [22] , [90] , [96] . Fig.…”
Section: Resultsmentioning
confidence: 99%
“…Nosocomial infections (NIs) is defined infections that occurs in patients due to treatment procedures consequence of hospitalization in hospital or medical centers [66] , [60] , [7] , [82] . Nosocomial infections occur among patient's 48 h or more following hospital admission [66] , [22] . According to reported Center Disease Control (CDC) in the United States, 60,0000–80,0000 cases of needle stick injuries each year occur among health care worker [89] , [95] , [97] .…”
“…Criteria for the diagnosis of NIs were based on the National Nosocomial Infections Surveillance (NNIS). 28,29 In the present study, hospital supervisors of the infection control reported cases of NIs and NSIs, wards in which occurred and the sampling methods. NIs sampling was performed at random from patients with infections.…”
“…pneumoniae and those resistant to carbapenems as well [12]. Polymyxins combined with carbapenems, βlactam enzyme inhibitors and tigecycline are effective in the treatment of pulmonary infections, which could effectively reduce the adverse reactions of drugs [13]. Additionally, targeted, limited use of antimicrobials can be bene cial in patients with gastrointestinal infection.…”
Section: Multivariate Logistic Regression Of Preoperative and Operati...mentioning
Background Internal hospital infection is one of the major public health concerns worldwide. To investigate the etiological characteristics and risk factors of infections after colorectal cancer(CRC) surgery and the formulation of targeted infection control strategies.
Methods This is a retrospective analysis of 1500 patients from colorectal cancer patients from General Surgery between March 2018 and March 2022，Anyang Tumor Hospital. Based on pathogen distribution and results of drug sensitivity testing, pattern of pathogens and drug resistance in infection in hospitalized patients with with colonic malignancy were analyzed. We conducted univariate and multivariate logistic regression analyses to determine the risk factors of infections that are associated with postoperative colorectal cancer.
Results Infection cases were noted in 5.20% of all 1500 cases (78 of 1500 CRC patients). Drug resistance pattern showed that 88.89% of the implicated coagulase-negative staphylococci species and 40% of the implicated Acinetobacter species were meropenem-resistant. Considering all infection sites, age >60 years (OR=2.190, P=0.002), diabetes mellitus (OR=2.044, P=0.005), operation time >3h (OR=2.178, P=0.002) ), hospitalization time >10d (OR=1.793, P=0.017), parenteral nutrition (OR=2.797, P=0.000), indwelling catheter (OR=1.699, P=0.038), mechanical ventilation (OR=2.294, P=0.001) and the usage of drainage tube (OR=3.455, P=0.000) were risk factors at multivariate analysis.
Conclusions: Post-operative infections may negatively affect surgical outcomes. Based on the greatest available evidence,important preoperative risk factors for postoperative colorectal cancer infections have been identified. Knowledge on risk factors may influence treatment and procedure-related decisions, and possibly reduce the postoperative infection rate.
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