The Prevalence of Helicobacter Pylori Infection in Benghazi, Libya

Almehdawi, Khaled A.; Ali, Ramadan H.

doi:10.9790/0853-150787377

Cited by 7 publications

(10 citation statements)

References 16 publications

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“…Similarly, the magnitude of the infection in the current study was lower than those reported from African countries such as 75.5% in Morocco [29], 65 % Tanzania [30], and 80% in Nigeria [31] and comparable with finding 56.5% reported from Libya [32]. On the contrary, the higher magnitude was observed than 12.5% reported from another study in Nigeria [33].…”

Section: The Magnitude Of H Pylori Infection Among Adult Dyspeptic Psupporting

confidence: 82%

The Magnitude and associated factors of Helicobacter pylori infection among adult dyspeptic patients attending Bokoji Hospital, Southeast Ethiopia

Kenea¹,

Negawo²,

Lemessa³

et al. 2020

Preprint

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Background: Helicobacter pylori infection is the most common chronic bacterial infection and there were approximately 4.4 billion individuals with H pylori infection worldwide. Among those, hundreds of millions of people develop peptic ulcer disease during their lifetime and still tens of millions might progress to gastric cancer. Hence, early information is very important to prevent upper gastrointestinal complications. Consequently, the current study aimed to assess the magnitude and associated risk factors of Helicobacter pylori infection among adult dyspeptic patients attending Bokoji hospital, Southeast Ethiopia.Methods: A hospital-based cross-sectional study involving 348 adult dyspeptic patients attending Bokoji hospital was carried out from July 16 to October 31, 2019. About 50 mg of fresh stool and 60 µl of capillary blood were collected from each dyspeptic patient and analyzed for detection of Helicobacter pylori antigens, presence of intestinal parasites and ABO blood grouping respectively. Data were entered using Epi Info 7 and Statistical analysis was done using SPSS version 21 and a p-value less than 0.05 was considered as statistically significant.Results: The overall magnitude of Helicobacter pylori infection was 47.7%. The magnitude of H. pylori infection was almost two times higher in patients who do not have a habit of handwashing after toilet visit than those who wash their hand's habit of handwashing after visiting toilet (AOR 2.241, 95% CI (1.410, 3.563) and alcohol drinking habit (AOR 1.796, 95% CI (1.087, 2.968). Conclusions: The magnitude of H. pylori was high in the study area and associated with handwashing habits after toilet use and alcohol drinking habits. Therefore, the community could be educated on the handwashing habit to minimize H. pylori infections.

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Section: The Magnitude Of H Pylori Infection Among Adult Dyspeptic Psupporting

confidence: 82%

The Magnitude and associated factors of Helicobacter pylori infection among adult dyspeptic patients attending Bokoji Hospital, Southeast Ethiopia

Kenea¹,

Negawo²,

Lemessa³

et al. 2020

Preprint

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“…Unlikely, these factors were previously reported to have a significant association with H. pylori infection rates. (21,28,46) Eating spicy food showed a significant correlation with the prevalence of H. pylori among patients in the present study. Sixty seven out of the 86 cases who frequently ate spicy food were positive for H. pylori (77.9%) compared to 6 cases out 14; who didn't eat such food (42.9%) (x 2 =7.504, p= 0.019).…”

Section: Discussionsupporting

confidence: 54%

“…This is in line with the findings of Bakka et al, (2009) (47) and opposite to those reported by El-Kady, (2018)(21) and Almehdawi and Ali (2016). (28) No significant association between level of education of patients and H. pylori prevalence rate was found. On the other hand, an inverse association between the level of education and H. pylori infection was reported in previous studies .…”

Section: Discussionmentioning

confidence: 91%

“…This finding is in line with previous studies as those carried out by EL-Kady(2018) (21) , Abdallah et al, (2014) (22) , Lim et al, (2013)(23), Vilaichone et al, (2013) (24) and Hanafi and Mohamed,(2013). (25) On the other hand, Mohamed et al, (2016) (26) , Laszewicz et al, (2014) (27) and Almehdawi and Ali (2016) (28) , reported no significant association between residence and prevalence of H. pylori infection. Currently, there was no significant association between the socioeconomic standard of the patients and the prevalence of H. pylori.…”

Section: Discussionmentioning

confidence: 99%

“…Similarly, in most studies, no significant association between smoking and H. pylori infection was reported. (28,(42)(43)(44) Meanwhile, other authors reported that smokers were significantly at higher risk of acquiring H. pylori infection. (21,25,45,46) Regards the dietary habits of the participants in the current work; drinking coffee and tea and skipping meals were not significantly implicated to increase the risk of H. pylori infection.…”

Section: Discussionmentioning

confidence: 99%

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The Plausibility of Helicobacter Pylori and CagA Strains Related Infertility Among Males in Alexandria, Egypt

El-Kady

2019

Journal of High Institute of Public Health

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Background: Helicobacter pylori (H. pylori), especially the strains expressing cytotoxin-associated gene A (CagA), besides causing gastric diseases, may also involve other systems including the reproductive system leading to infertility. In males, antibodies produced against H. pylori flagella may cross react with spermatozoa flagella; due to antigenic mimicry between them. Infected males have decreased sperm count, motility and viability, reduced numbers of normally shaped sperms and augmented systemic levels of inflammatory cytokines. Objective(s): to detect H. pylori-related infertility prevalence among males; and to address the possibility that such infection may play a detrimental role in their semen quality. Methods: One hundred infertile male patients attending a private hospital in Alexandria were screened for H. pylori by enzyme linked immunosorbent assay (ELISA). CagA strains were further identified using CagA IgG ELISA. Semen analysis was performed to assess semen quality as regards sperm count, motility, vitality and morphology. Results: H. pylori seropositivity was 73% (73 out of 100) among screened cases. Sixty out of the 73 positive cases for H. pylori IgG (82.19%) were CagA strains. H. pylori prevalence was significantly higher among the group of patients with idiopathic infertility (79.7%) than among those who had one or more diagnosed causes of infertility; p value= 0.024. CagA status significantly influenced the quality of semen among infected cases compared to uninfected ones. (p value<0.001). Conclusion: H. pylori infection; specially by CagA strains can be responsible for cases of idiopathic infertility in males through its negative effect on semen quality.

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Helicobacter pylori infection in Africa: comprehensive insight into its pathogenesis, management, and future perspectives

Emmanuel,

Peter,

Peter

et al. 2024

J.Umm Al-Qura Univ. Appll. Sci.

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Helicobacter pylori is a widespread bacterium that has effectively colonized half of the global population, with Africa having over 70% of the total burden of H. pylori infections (HPI). Considering its acknowledged classification of as bacterial carcinogens and their significant contribution to the development of gastrointestinal disorders such as gastritis, peptic ulcers, and gastric neoplasia, together with their growing resistance to antibiotics. Gaining insight into the etiology of this organism is crucial in order to investigate and develop appropriate treatment strategies. Furthermore, the rise of bacteria that are resistant to antibiotics presents an extra danger in managing this detrimental bacterium. Our review focuses on investigating the presence of H. pylori in Africa and analyzing the various factors that contribute to its extensive prevalence. We simplified the complex mechanisms that H. pylori utilizes to flourish in the human body, with a specific emphasis on its virulence factors and antibiotic resistance. These variables pose significant challenges to conventional treatment strategies. In addition, we analyze both conventional and developing diagnostic methods, as well as the current treatment approaches implemented in various African nations. In addition, we tackle the distinct healthcare obstacles of the region and put-up practical remedies. The main goal of this review is to improve the formulation of more efficient methods for the management and treatment of HPI in Africa.

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The Prevalence of Helicobacter Pylori Infection in Benghazi, Libya

Cited by 7 publications

References 16 publications

The Magnitude and associated factors of Helicobacter pylori infection among adult dyspeptic patients attending Bokoji Hospital, Southeast Ethiopia

The Magnitude and associated factors of Helicobacter pylori infection among adult dyspeptic patients attending Bokoji Hospital, Southeast Ethiopia

The Plausibility of Helicobacter Pylori and CagA Strains Related Infertility Among Males in Alexandria, Egypt

Helicobacter pylori infection in Africa: comprehensive insight into its pathogenesis, management, and future perspectives

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