The prevalence and predictors of cardiovascular diseases in Kherameh cohort study: a population-based study on 10,663 people in southern Iran

Abstract

Background The prevalence of cardiovascular disease (CVD) is rapidly increasing in the world. The present study aimed to assess the prevalence and Predictors factors of CVD based on the data of Kherameh cohort study. Methods The present cross-sectional, analytical study was done based on the data of Kherameh cohort study, as a branch of the Prospective Epidemiological Studies in Iran (PERSIAN). The participants consisted of 10,663 people aged 40–70 years. CVD was defined as suffering from ischemic heart diseases including heart failure, angina, and myocardial infarction. Logistic regression was used to model and predict the factors related to CVD. Additionally, the age-standardized prevalence rate (ASPR) of CVD was determined using the standard Asian population. Results The ASPR of CVD was 10.39% in males (95% CI 10.2–10.6%) and 10.21% in females (95% CI 9.9–10.4%). The prevalence of CVD was higher among the individuals with high blood pressure (58.3%, p < 0.001) as well as among those who smoked (28.3%, p = 0.018), used opium (18.2%, p = 0.039), had high triglyceride levels (31.6%, p = 0.011), were overweight and obese (66.2%, p < 0.001), were unmarried (83.9%, p < 0.001), were illiterate (64.2%, p < 0.001), were unemployed (60.9%, p < 0.001), and suffered from diabetes mellitus (28.1%, p < 0.001). The results of multivariable logistic regression analysis showed that the odds of having CVD was 2.25 times higher among the individuals aged 50–60 years compared to those aged 40–50 years, 1.66 folds higher in opium users than in non-opium users, 1.37 times higher in smokers compared to non-smokers, 2.03 folds higher in regular users of sleeping pills than in non-consumers, and 4.02 times higher in hypertensive individuals than in normotensive ones. Conclusion The prevalence of CVD was found to be relatively higher in Kherameh (southern Iran) compared to other places. Moreover, old age, obesity, taking sleeping pills, hypertension, drug use, and chronic obstructive pulmonary disease had the highest odds ratios of CVD.

Relationship between opium consumption and lipid profile in drug addicts and non-addicts on Kharameh cohort study

“…Triglycerides above 150 mg/dL are considered high and abnormal triglycerides, and total cholesterol above 200 mg/dL is considered high cholesterol. Furthermore, LDL levels greater than 130 mg/dL are considered high, while HDL levels less than 40 for men and less than 50 for women are considered low HDL (20,55).…”

The Association between Index of Nutritional Quality (INQ) and Obesity: Baseline Data of Kharameh Cohort

“…Kharameh study was started with 10,667 participants with an age range of 40–70 in 2014. All participants of Kharameh cohort study were included in our research through census [ 21 ].…”

A Systematic Review of Major Cardiovascular Risk Factors: A Growing Global Health Concern

“…Existing research recognizes that the critical role played for the forthcoming measurements of global burden in CVD will be increased, informed by new vital registration systems [35][36][37][38][39][40]. Sustainable development goals, along with human resources, technical capacity, infrastructures, and funding, will be in need, particularly in LMICs [38][39][40][41][42][43][44][45].…”