The Preparation of Some Cyclic Acetals

Keywords: Lithiation / Substituent effects / Benzophenones / 1,3-Dioxolanes 2-Aryl-2-(chloroaryl)-1,3-dioxolanes 4 were lithiated ortho to the ketal group of the chloroaryl ring by treatment with butyllithium in THF between −78 and 0°C. The site selectivity of some of the deprotonation reactions was rationalized by the long-range effect of the 4-chloro substituent. The lithio species thus generated were treated with various elec-

show abstract

“…Ethylene ketals 4a − s are new compounds,21 which were obtained by conventional methods (Scheme , Table 1). 22−24…”

Section: Resultsmentioning

confidence: 99%

Lithiation of 2‐Aryl‐2‐(chloroaryl)‐1,3‐dioxolanes and Its Application in the Synthesis of New ortho‐Functionalized Benzophenone Derivatives

2004

View full text Add to dashboard Cite

show abstract

“…[3][4][5][6][7][8] We were seeking a simple and environmentally benign synthesis of benzophenone and acetophenone ethylene ketals. Most of the reported methods that avoided the drawbacks of the traditional protection methods (eg.…”

Section: Methodsmentioning

confidence: 99%

Microwave assisted synthesis of benzophenone and acetophenone ethylene ketals

Lukács¹,

Porcs-Makkay²,

Komáromi³

et al. 2007

Arkivoc

View full text Add to dashboard Cite

Dedicated to Professor Csaba Szántay on the occasion of his 80th birthdayAbstract A simple and convenient synthesis of acetophenone and benzophenone ethylene ketals was elaborated by performing the reaction of ethylene glycol in toluene in the presence of PTSA, under microwave irradiation with simultaneous removal of the water so formed. Under these conditions 100 % conversion and high yields were obtained within short reaction times.

show abstract

“…Physical and spectroscopic data. For 2a: bp 125-127 °C/30 Torr (lit., 11 101 °C/10 Torr). For 2b: bp 118-120 °C/32 Torr (lit., 12 60 °C/0.35 Torr).…”

Section: Methodsmentioning

confidence: 99%

Montmorillonite Clay Catalysis. Part 2.1 An Efficient and Convenient Procedure for the Preparation of Acetals catalysed by Montmorillonite K-10

Li¹,

Li²,

Li³

et al. 1997

J. Chem. Res.

View full text Add to dashboard Cite

The Preparation of Some Cyclic Acetals

Cited by 48 publications

References 0 publications

Lithiation of 2‐Aryl‐2‐(chloroaryl)‐1,3‐dioxolanes and Its Application in the Synthesis of New ortho‐Functionalized Benzophenone Derivatives

Lithiation of 2‐Aryl‐2‐(chloroaryl)‐1,3‐dioxolanes and Its Application in the Synthesis of New ortho‐Functionalized Benzophenone Derivatives

Microwave assisted synthesis of benzophenone and acetophenone ethylene ketals

Montmorillonite Clay Catalysis. Part 2.1 An Efficient and Convenient Procedure for the Preparation of Acetals catalysed by Montmorillonite K-10

Contact Info

Product

Resources

About