The pre-ejection period as an antepartum indicator of fetal well-being

Organ, L.W.; Bernstein, A.; Hawrylyshyn, P.

doi:10.1016/0002-9378(80)90890-x

Cited by 38 publications

(21 citation statements)

References 15 publications

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“…Positive correlations between PEP and gestational age, and PEP and QRS width, were seen here, consistent with several earlier studies [9,10,19] . These trends were apparent within individual subjects, demonstrating the precision of our measurements.…”

Section: Commentssupporting

confidence: 80%

“…A proposed explanation for the increasing PEP with gestational age is the increase in myocardial mass and the concomitant prolongation of ventricular depolarization ( fig. 5 a, c) [9] . While most systolic time intervals increase with gestational age, it is notable that ejection time did not increase and in fact showed a decrease that was not statistically significant ( fig.…”

Section: Commentsmentioning

confidence: 99%

“…In particular, while onset of ventricular ejection is progressively delayed, reflected in the lengthening of PEP, ejection time stays the same or decreases, comprising a smaller fraction of the cardiac cycle, despite the fact that stroke volume continually increases during gestation. Across sessions, PEP was found to correlate positively with RR [7,9] . On a beat-to-beat basis, however, an inverse relationship between PEP and the preceding RR was seen.…”

Section: Commentsmentioning

confidence: 99%

“…Organ et al . [9] found that PEP shortens with acute hypoxemia. However, during sustained and severe hypoxemia, PEP becomes prolonged.…”

Section: Introductionmentioning

confidence: 99%

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Assessment of Left Ventricular Pre-Ejection Period in the Fetus Using Simultaneous Magnetocardiography and Echocardiography

Mensah-Brown

Wakai²,

Cheulkar³

et al. 2010

Fetal Diagn Ther

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Introduction: Fetal magnetocardiography (fMCG) is a promising new technique for assessing fetal rhythm; however, no prior studies have utilized fMCG to evaluate human fetal electromechanical physiology. Pre-ejection period (PEP) is an important measure of the electromechanical activation of the heart, and is altered by disease states and arrhythmias. Materials and Methods: A novel technique was used to assess fetal PEP and its relationship to other fetal systolic time intervals, RR interval, and gestational age (GA). 25 normal human fetuses between 19 and 38 weeks’ gestation were studied using simultaneous pulsed Doppler ultrasound and fMCG. Correlations among PEP, ejection time, QRS width and RR interval were assessed using linear regression. Results: Across all subjects, PEP was found to correlate with GA (R = 0.57, p < 0.0001), QRS width (R = 0.35, p = 0.026), and RR interval (R = 0.37, p = 0.018). In individual sessions, PEP negatively correlated beat-to-beat with the preceding RR interval. Conclusion: PEP exhibits developmental trends that provide a better understanding of the normal development of the human fetal heart.

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Section: Commentssupporting

confidence: 80%

Section: Commentsmentioning

confidence: 99%

Section: Commentsmentioning

confidence: 99%

“…Organ et al . [9] found that PEP shortens with acute hypoxemia. However, during sustained and severe hypoxemia, PEP becomes prolonged.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Assessment of Left Ventricular Pre-Ejection Period in the Fetus Using Simultaneous Magnetocardiography and Echocardiography

Mensah-Brown

Wakai²,

Cheulkar³

et al. 2010

Fetal Diagn Ther

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“…According to our experience, the reproduc ibility of the measurements is good when the equipment and technique described here are employed. The RPT has been studied to as sess myocardial performance [12,32], It has been supposed to be closely related to the left ventricular systolic time intervals, mainly to the preejection period [32,33]. The left ven tricular systolic time intervals are not af fected by the severity of the RDS [34], If the RPT-rcflects the left ventricular preejection period, our results are in agreement with the observations suggesting that the myocardial performance is normal also in severe RDS.…”

Section: Discussionmentioning

confidence: 99%

Cardiovascular Monitoring in Infants with Respiratory Distress Syndrome

Korvenranta¹,

Kero²,

Välimäki³

1983

Neonatology

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Heart rate, short-term heart rate variability, long-term heart rate variability (LTV), mean arterial blood pressure and R-to-pulse time were recorded in 28 infants during the acute phase of respiratory distress syndrome (RDS). The patients were classified by a clinical scoring system into three classes related to the severity of the disease. The LTV was initially significantly (p < 0.01) lower in infants with severe RDS (class III) than in those with moderate or mild disease (classes II and I). Only in class III the LTV increased significantly (p < 0.001) during recovery. Also the mean arterial blood pressure was decreased in class III during the first 24 h of life. The R-to-pulse time proved not to be related to the severity of RDS. Reasonable assistance was achieved by multiparametric circulatory monitoring: a considerably disturbed circulatory control (tendency to hypotension and attenuated chronotropic cardiac control) was observed in the most severe form of RDS. No specific circulatory therapy was applied on the basis of the findings.

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