The Potentiometric Performances of Membrane Electrodes Based on Tetracycline Antibiotics

Baek, Jong-Gyu; Rhee, Insook; Paeng, Ki‐Jung

doi:10.5229/jkes.2006.9.3.132

Cited by 3 publications

(5 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The basic PVC membrane electrodes (membrane 1 and 2 in Table 1) incorporating TC were prepared and its potentiometric performances as cation selective electrodes were reported in our previous work. 9 According to those data, the PVC electrode based on TC exhibits a good Nernstian response (26.6 mV/dec) for calcium ion (Ca , since Ca 2+ tends to form more voluminous ion-ligand complex stoichiometry and its larger radius.…”

Section: +mentioning

confidence: 86%

The Composition Dependence Selectivity Changes by Plasticizer at the Cation Sensors Based on Tetracycline Antibiotics

Baek¹,

Kim²,

Paeng³

et al. 2008

Bulletin of the Korean Chemical Society

View full text Add to dashboard Cite

The performances of tetracycline based cation selective polymeric membrane electrodes of many sets with different plasticizers were investigated as the selectivity of ion-selective electrodes and optodes are greatly influenced by membrane solvent and also controlled by plasticizers. The membrane 1 with Bis(2-ethylhexyl) sebacate (DOS) and additive shows good potentiometric performance toward Ca 2+ (slope: 27.8 mV per decade; DL: −4.52) including selectivity. Contrastingly, membrane 4 with Dibutyl phthalate (DBP) shows nearNernstian response, it has also shown the best measuring range and detection limit for Ca 2+ (29.5 mV and −5.10) and Mg 2+ (24.4 mV and −5.04) and the least selectivity has been also observed between Ca 2+ and Mg 2+. When the membrane 1 and 4 were used together to flow system, we could determine the concentration of Ca 2+ and Mg 2+, simultaneously.

show abstract

Section: +mentioning

confidence: 86%

The Composition Dependence Selectivity Changes by Plasticizer at the Cation Sensors Based on Tetracycline Antibiotics

Baek¹,

Kim²,

Paeng³

et al. 2008

Bulletin of the Korean Chemical Society

View full text Add to dashboard Cite

show abstract

“…7,8) The first of those papers, 6) by changing the plasticizer, sensors responded to the Ca and Mg ions with different selectivity. In that paper, authors suggested the binding site is keto-enolate site of TC.…”

Section: Resultsmentioning

confidence: 99%

“…[1][2][3] The binding ability to metal ions of tetracycline (TC) antibiotics has obtained much attention because TCs have a very good affinity with divalent ions such as Mg(II) and Ca(II) ions. [4][5][6] . Selectivity is obviously one of the most important characteristics of the sensors.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The Potentiometric Performances of the Cation Selective Electrodes based on Tetracycline and Chemically Modified Tetracycline

Kang¹,

Rhee²,

Paeng³

2011

Journal of Electrochemical Science and Technology

Self Cite

View full text Add to dashboard Cite

:Metal-binding antibiotics are very attractive choices as cation selective ionophores. The ability of tetracycline (TC) antibiotics to bind to metal ions has obtained much attention. TCs exhibit the potentiometric performance changes for various cations dependant on several experiment conditions. In this report, we investigated the potentiometric performance changes of TC as the modification of TC's possible metal binding site. We found that the selectivity alter with the blocking main binding site of ionophores for cations. And, additionally it is possible to control the selectivity of sensors with chemical modification of ionophores.

show abstract

“…Furthermore, the modification of polymeric membranes with tetracycline has also been evaluated for calcium analysis, in the presence of mono and divalent cations (Baek, Rhee, Paeng, 2006).…”

Section: Tetracyclines and Quinolonesmentioning

confidence: 99%

Electrochemical biosensors in pharmaceutical analysis

Gil

Melo

2010

Braz. J. Pharm. Sci.

View full text Add to dashboard Cite

Given the increasing demand for practical and low-cost analytical techniques, biosensors have attracted attention for use in the quality analysis of drugs, medicines, and other analytes of interest in the pharmaceutical area. Biosensors allow quantification not only of the active component in pharmaceutical formulations, but also the analysis of degradation products and metabolites in biological fluids. Thus, this article presents a brief review of biosensor use in pharmaceutical analysis, focusing on enzymatic electrochemical sensors.
Em virtude do aumento da demanda por técnicas analíticas simples e de baixo custo, os biossensores têm atraído a atenção para a análise de fármacos, medicamentos e outros analitos de interesse em controle de qualidade de medicamentos. Os biossensores permitem a quantificação não somente de princípio ativo em formulações farmacêuticas, mas também de produtos de degradação e metabólitos em fluídos biológicos, bem como análise de amostras de interesse clínico e industrial, além de possibilitar a determinação de enantiômeros. Desta forma, este artigo objetiva fazer uma breve revisão a respeito do emprego de biossensores em análise farmacêutica, com ênfase em sensores eletroquímicos enzimáticos

show abstract

The Potentiometric Performances of Membrane Electrodes Based on Tetracycline Antibiotics

Cited by 3 publications

References 8 publications

The Composition Dependence Selectivity Changes by Plasticizer at the Cation Sensors Based on Tetracycline Antibiotics

The Composition Dependence Selectivity Changes by Plasticizer at the Cation Sensors Based on Tetracycline Antibiotics

The Potentiometric Performances of the Cation Selective Electrodes based on Tetracycline and Chemically Modified Tetracycline

Electrochemical biosensors in pharmaceutical analysis

Contact Info

Product

Resources

About