The Potential Use of Gingival Crevicular Blood for Measuring Glucose to Screen for Diabetes: An Examination Based on Characteristics of the Blood Collection Site

Strauss, Shiela M.; Wheeler, Alla J.; Russell, Stefanie L.; Brodsky, Allison; Davidson, Robert M.; Gluzman, Rima; Li, Lin; Malo, Roberto Galao; Salis, Bram; Schoor, Robert; Tzvetkova, Krassimira

doi:10.1902/jop.2009.080542

Cited by 40 publications

(41 citation statements)

References 43 publications

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“…This finding of the present study is consistent with the most of previous studies of Wu et al, 11 Ardakani et al, 12 Shetty et al, 13 and Strauss et al 14 on the correlation between gingival crevicular and capillary blood glucose levels who also reported that GCB samples are suitable to screen for DM in individuals with sufficient bleeding on probing (BOP).…”

Section: Resultssupporting

confidence: 93%

Noninvasive Technique for estimating Blood Glucose Levels among diabetic Patients

Shylaja

Sam

et al. 2016

The Journal of Contemporary Dental Practice

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Aim: The present study was aimed to assess the fasting and postprandial gingival crevicular blood (GCB) glucose and finger stick blood glucose measurements using a glucometer. Materials and methods:A total of 30 subjects with periodontitis and positive bleeding on probing were considered. Subjects were instructed to report to the department after overnight fasting. Gingival crevicular blood samples were collected from anterior region showing bleeding on probing followed by finger stick blood sample collection. Then, the patients were instructed to take 75 gm of glucose and after 2 hours blood samples from two sites were collected similarly. Results were analyzed using unpaired t test and Pearson's correlation. Results:Mean glucose levels form GCB and finger stick blood did not differ either during fasting or postprandial (p > 0.05). Significant correlation was found between GCB glucose levels and capillary finger stick blood (CFB) glucose levels during fasting Conclusion:Periodontal probing can be considered as an alternate noninvasive method of blood glucose estimation for screening of diabetes mellitus (DM). The technique described is safe, easy to perform, and helps to increase the frequency of diabetes screening in dental office.Clinical significance: The GCB from probing can be a good source of blood for estimating blood glucose levels and screening for diabetes using portable glucose monitors. Also, it will be a simple and relatively inexpensive in office screening procedure for any patient suspected to have diabetes.

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Section: Resultssupporting

confidence: 93%

Noninvasive Technique for estimating Blood Glucose Levels among diabetic Patients

Shylaja

Sam

et al. 2016

The Journal of Contemporary Dental Practice

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“…12 Since periodontal inflammation with or without complication factor of DM is known to produce ample extravasate of blood during diagnostic periodontal examination, it can be used for the routine random blood glucose level estimation. 13 Strauss et al 14 also reported that GCB samples were suitable in persons with sufficient bleeding on probing, to obtain a sample without touching the tooth or the gingival margin (i.e., in patients having the basic clinical signs of gingivitis or periodontal disease). Moreover, the technique is more familiar and less traumatic to the patient than a finger puncture.…”

Section: Discussionmentioning

confidence: 99%

Estimation of gingival crevicular blood glucose level for the screening of diabetes mellitus: A simple yet reliable method

Parihar

Tripathi

Parihar

et al. 2016

Journal of Oral Biology and Craniofacial Research

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“…[12] Strauss et al in their study reported that gingival crevicular samples are suitable to screen for diabetes in individuals with suffi cient bleeding on probing. [13] Sarlati et al stated in patients with diabetes this method revealed suffi cient agreement. [14] Hence, they concluded that gingival crevicular blood can be used for testing blood glucose level during the periodontal examination in diabetic periodontal patients but not in non-diabetics.…”

Section: Discussionmentioning

confidence: 99%

Assessment of blood glucose levels in diabetic patients with periodontitis: A three-way method using gingival crevicular, capillary, and venous blood

Penmetsa¹,

devi²,

Dwarakanath³

2016

IDJAR

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Background:To test the feasibility of using gingival crevice blood collected during routine periodontal examination and to estimate the blood glucose levels using glucometer (Accu-Chek Active). Materials and Methods: A total of 50 patients with a history diabetes mellitus and with chronic periodontitis were selected. From all, the patients fasting venous blood glucose was estimated. Blood oozing from gingival tissues during periodontal examination was collected on the strip of the glucose self-monitoring device (Accu-Chek). Then, the fi nger stick capillary blood was collected, and glucose levels were estimated using glucometer. Results:The comparison between venous capillary and gingival crevicular showed a strong correlation with a P < 0.001. Conclusion:The data from this study have shown that gingival crevicular blood collected during the periodontal examination may be used to analyse blood glucose levels in diabetic patients.

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The Potential Use of Gingival Crevicular Blood for Measuring Glucose to Screen for Diabetes: An Examination Based on Characteristics of the Blood Collection Site

Abstract: GCB samples were suitable to screen for diabetes in persons with sufficient BOP to obtain a sample without touching the tooth or gingival margin (i.e., in patients having the basic clinical signs of gingivitis or periodontal disease).

Cited by 40 publications

References 43 publications

Noninvasive Technique for estimating Blood Glucose Levels among diabetic Patients

Noninvasive Technique for estimating Blood Glucose Levels among diabetic Patients

Estimation of gingival crevicular blood glucose level for the screening of diabetes mellitus: A simple yet reliable method

Assessment of blood glucose levels in diabetic patients with periodontitis: A three-way method using gingival crevicular, capillary, and venous blood

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