The potential of the brown seaweed Sargassum polycystum against acne vulgaris

Kok, Jamie Mei-Lin; Jee, Jap-Meng; Chew, Lye Yee; Wong, Ching-Lee

doi:10.1007/s10811-016-0825-4

Cited by 20 publications

(6 citation statements)

References 23 publications

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“…Sargassum vulgare methanol extract was investigated for its phytochemical constituents and it was observed the presence of polysaccharides, alkaloids, phytosterols, terpenoids, fats, and fixed oils These qualitative phytochemicals results are consistent with the results of some Sargassum species as Sargassum wightii, Sargassum polycystum, Sargassum duplicatum, Sargassum angustifolium, Sargassum oligocystum and Sargassum boveanum and show disagreement in the presence of polyphenolic compounds, tannins, flavonoids, and saponins [7] [20] [21]; [38][32].…”

Section: Discussionsupporting

confidence: 65%

Preliminary phytochemical screening for various secondary metabolites, quantitative and qualitative analysis of Yemeni brown seaweed Sargassum vulgare

al-hashdy¹,

El-Shaibany²,

Raweh³

et al. 2022

GSC Biol. Pharm. Sci.

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Sargassum Vulgare was collected from the Red sea coastlines, Al-Hodeida, Yemen, and dried. The dried powder was subjected to consecutive extraction by methanol. The dried methanol extract was subjected to solvent fractionation (n-hexane-chloroform-ethyl acetate and n-butanol solvents). Sargassum vulgare polysaccharides (S.R1P, S.R1M, S.R5s, and S.R5ss) were isolated by precipitation with methanol. [19] The methanol extract and n-hexane fraction were evaluated phytochemically. The physicochemical characteristics and FT-IR analysis of Sargassum vulgare polysaccharides (S.R1P, S.R1M, S.R5s, and S.R5ss) were investigated, the chemical composition of the Sargassum vulgare n-hexane fraction was evaluated by Gas Chromatography-Mass Spectrometry (GC-MS) analysis [8]. Phytochemical investigation revealed that both methanol extract and n-hexane fraction of Sargassum vulgare contained alkaloids, phytosterols, terpenoids, fats, and fixed oils. Moreover, Sargassum vulgare methanol extract exhibited a high amount of carbohydrates (41.33%) mainly polysaccharides [40][41][42]. The physicochemical characteristics and FT-IR analysis of polysaccharides (S.R1P, S.R1M, S.R5s, and S.R5ss) revealed that all the obtained polysaccharides were alginates with traces of sulfate polysaccharides except S.R1M. [30][34][35]

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Section: Discussionsupporting

confidence: 65%

Preliminary phytochemical screening for various secondary metabolites, quantitative and qualitative analysis of Yemeni brown seaweed Sargassum vulgare

al-hashdy¹,

El-Shaibany²,

Raweh³

et al. 2022

GSC Biol. Pharm. Sci.

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“…ABTS (2,2 -azino-bis3-ethylbenzthiazoline-6-sulfonic) assay was performed to evaluate the antioxidant potential of the fruit extracts following protocols set by Kok et al with slight modifications [30]. The assay was conducted by placing 1 mL ABTS solution in a microtube, to which 10 µL of sample (50 mg/mL) or Trolox (0, 15, 20, 25, 30 and 35 µM) was added.…”

Section: Antioxidant Assaymentioning

confidence: 99%

Hydroethanolic Extract of Prunus domestica L.: Metabolite Profiling and In Vitro Modulation of Molecular Mechanisms Associated to Cardiometabolic Diseases

et al. 2022

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High consumption of fruit and vegetables has an inverse association with cardiometabolic risk factors. This study aimed to chemically characterize the hydroethanolic extract of P. domestica subsp. syriaca fruit pulp and evaluate its inhibitory activity against metabolic enzymes and production of proinflammatory mediators. Ultra-high-performance liquid chromatography high-resolution mass spectrometry(UHPLC-HRMS) analysis showed the presence of hydroxycinnamic acids, flavanols, and glycoside flavonols, while nuclear magnetic resonance(NMR) analysis showed, among saccharides, an abundant presence of glucose. P. domestica fruit extract inhibited α-amylase, α-glucosidase, pancreatic lipase, and HMG CoA reductase enzyme activities, with IC50 values of 7.01 mg/mL, 6.4 mg/mL, 6.0 mg/mL, and 2.5 mg/mL, respectively. P. domestica fruit extract inhibited lipopolysaccharide-induced production of nitrite, interleukin-1 β and PGE2 in activated J774 macrophages. The findings of the present study indicate that P. domestica fruit extracts positively modulate in vitro a series of molecular mechanisms involved in the pathophysiology of cardiometabolic diseases. Further research is necessary to better characterize these properties and their potential application for human health.

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“…Researchers have looked into the potential for marine-derived compounds from Undaria pinnatifida, Octopus vulgaris, and Sargassum polycystum, to improve skin pigmentation, as well as to possess antioxidant, anti-inflammatory, and immunomodulatory capabilities. These substances (compounds 22 – 24 in Figure 9 ) also contain octaphlorethol A, fucoidan, and fucoxanthin [ 180 , 181 , 182 , 183 , 184 , 185 ]. Numerous studies have looked into how octaphlor-ethol A affects skin conditions and pigmentation.…”

Section: Natural Hyperpigmentation Treatmentmentioning

confidence: 99%

Skin Pigmentation Types, Causes and Treatment—A Review

Thawabteh,

Jibreen,

Karaman

et al. 2023

Molecules

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Human skin pigmentation and melanin synthesis are incredibly variable, and are impacted by genetics, UV exposure, and some drugs. Patients’ physical appearance, psychological health, and social functioning are all impacted by a sizable number of skin conditions that cause pigmentary abnormalities. Hyperpigmentation, where pigment appears to overflow, and hypopigmentation, where pigment is reduced, are the two major classifications of skin pigmentation. Albinism, melasma, vitiligo, Addison’s disease, and post-inflammatory hyperpigmentation, which can be brought on by eczema, acne vulgaris, and drug interactions, are the most common skin pigmentation disorders in clinical practice. Anti-inflammatory medications, antioxidants, and medications that inhibit tyrosinase, which prevents the production of melanin, are all possible treatments for pigmentation problems. Skin pigmentation can be treated orally and topically with medications, herbal remedies, and cosmetic products, but a doctor should always be consulted before beginning any new medicine or treatment plan. This review article explores the numerous types of pigmentation problems, their causes, and treatments, as well as the 25 plants, 4 marine species, and 17 topical and oral medications now on the market that have been clinically tested to treat skin diseases.

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The potential of the brown seaweed Sargassum polycystum against acne vulgaris

Cited by 20 publications

References 23 publications

Preliminary phytochemical screening for various secondary metabolites, quantitative and qualitative analysis of Yemeni brown seaweed Sargassum vulgare

Preliminary phytochemical screening for various secondary metabolites, quantitative and qualitative analysis of Yemeni brown seaweed Sargassum vulgare

Hydroethanolic Extract of Prunus domestica L.: Metabolite Profiling and In Vitro Modulation of Molecular Mechanisms Associated to Cardiometabolic Diseases

Skin Pigmentation Types, Causes and Treatment—A Review

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