The Postsplenectomy Blood Picture

Lipson, Richard L.; Bayrd, Edwin D.; Watkins, Charles H.

doi:10.1093/ajcp/32.6.526

Cited by 82 publications

(33 citation statements)

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“…This finding corresponds to that presented by Ask-Upmark [1] in patients splenectomized because of traumatic lesions but without evidence of disease involving the spleen. The same hematologic characteristics have been reported in various other groups of patients [9,12,15,19].…”

Section: Discussionsupporting

confidence: 82%

“…Lipson et al [9] found no relation between the time lapse after splenectomy and the leukocytosis in patients who had undergone splenectomy 4 months to 11.5 years previously. We have found high concentrations of leukocytes immediately after splenectomy persisting at 40 x 109/1 for several months after surgery (S. Dreborg, unpublished observations).…”

Section: Discussionmentioning

confidence: 97%

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Hematological findings in the Norrbottnian type of Gaucher disease

et al. 1982

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A controlled study of hematological changes was performed on 14 patients with the Norrbottnian type of Gaucher disease, seven of whom had been splenectomized at least one year before the study. Each patient had two controls matched to age, sex and habitation. Before splenectomy the patients had slight to moderate microcytic, hypochromic anemia which changed after splenectomy to macrocytic, hypochromic anemia. The splenectomized patients had a high percentage of target cells (mean frequency 33%) and a significantly increased hypo-osmotic resistance of the erythrocytes which showed a positive correlation with the number of target cells. Before removal of the spleen the patients had slight leukopenia with a relative increase of mononuclear cells and moderate thrombocytopenia. In the splenectomized patients the thrombocyte count was normal and there was moderate leukocytosis with a persistent relative increase of lymphocytes.

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Section: Discussionsupporting

confidence: 82%

Section: Discussionmentioning

confidence: 97%

Hematological findings in the Norrbottnian type of Gaucher disease

et al. 1982

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“…Imaging of the spleen with technetium Tc 99m colloid liver-spleen scintigraphy and the finding of Howell-Jolly bodies within erythrocytes have been established as gold standards for the diagnosis of FAS. 2,3 Other imaging techniques, especially sonography, have been evaluated for their ability to detect FAS. Case reports have suggested that FAS might have a characteristic sonographic pattern.…”

mentioning

confidence: 99%

The small spleen: Sonographic patterns of functional hyposplenia or asplenia

Görg

Eichkorn

Zugmaier

2003

J of Clinical Ultrasound

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“…Traditionally, the Howell-Jolly body count is considered an indicator of markedly decreased splenic function (17). However, the clinical implication is limited by suboptimal sensitivity and a lack of objective counting (18).…”

Section: Measurement Of Splenic Immunologic Functionmentioning

confidence: 99%