The small spleen: Sonographic patterns of functional hyposplenia or asplenia

Görg, Christian; Eichkorn, Miriam; Zugmaier, Gerhard

doi:10.1002/jcu.10148

Cited by 27 publications

(27 citation statements)

References 10 publications

(8 reference statements)

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“…Still, the size of the spleen does not correlate well with its immunological function. In functionally asplenic patients, Gorg et al found a small spleen (less than 7r3 cm) on ultrasound in 83%, and abnormal Doppler-flow patterns (no flow or only hilar flow) in 88% [11]. However, the spleen significantly decreases in size at elderly age with retaining its function [12].…”

Section: Discussionmentioning

confidence: 99%

The absent and vanishing spleen: Congenital asplenia and hyposplenism-two case reports

et al. 2005

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Section: Discussionmentioning

confidence: 99%

The absent and vanishing spleen: Congenital asplenia and hyposplenism-two case reports

et al. 2005

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“…The second sonograpgic finding is the absence or reduction of parenchymal flow by colour Doppler sonography and CES. In a colour Doppler sonographic study reduced vascularity was seen in 88% of patients with FAS [29]. Although CES is sensitive for evaluation splenic vascularity prospective studies will be necessary to confirm whether the sonographic findings of a small spleen and reduced splenic vascularity by CES are sensitive and specific enough to diagnose FAS (Fig.…”

Section: The Small Sized Spleenmentioning

confidence: 95%

“…The first is small sized spleen [27,28]. In a retrospective study the spleen was small in 83% of the patient with proven asplenia [29]. A positive correlation of splenic size with splenic function has not been described yet, but cases of postoperative splenosis with a volume of 20-30 ml have been reported to have normal splenic function [30].…”

Section: The Small Sized Spleenmentioning

confidence: 97%

Contrast Enhanced Sonography for Diagnosis of (Peri-) Splenic Pathology

Görg¹,

Bert

2007

CMIR

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Objective: Ultrasound contrast agents in conjunction with contrast specific imaging techniques, are increasingly accepted in clinical use for diagnostic imaging in several organs. Contrast enhanced sonography (CES) of second generation contrast media have shown a spleen-specific uptake of the microbubble contrast agent. The aim of this review is to illustrate indications for the use of CES in patients with suspected (peri-)splenic pathology.Methods: This pictorial review based on the experience of transcutaneous CES in 180 consecutive adult patients with (peri-)splenic pathology diagnosed by B-mode sonography at an internal medicine center. CES studies were performed with a contrast-devoted unit (Acuson, Sequoia, Siemens medical solution) that had contrast-specific, continuous-mode software. A low mechanical index was used. A sulfur hexafluoride-based microbubble contrast medium (Sonovue ® , Bracco SpA, Milan, Italy) was injected.Results: On our experience there are six clinical conditions which indicates the use of CES for diagnosis of (peri-)splenic pathology: 1. the perisplenic tumor, 2. the small sized spleen, 3. the inhomogenous spleen of unknown cause, 4. the incidentally found hypoechoic splenic tumor, and 5. pain in the left upper quadrant, and 6. patients with blunt abdominal trauma. CES is of value 1. to diagnose or exclude accessory spleen, 2. to diagnose functional asplenia/hyposplenia, 3. to diagnose focal lesions in an inhomogenous spleen, 4. to diagnose high vascular splenic hemangioma, 5. to diagnose or exclude splenic infarction and splenic abscess, and 6. to diagnose splenic laceration.Conclusion: CES is of diagnostic value in several clinical circumstances to diagnose accessory spleen, functional asplenia, small sized splenic involvement, high vascular splenic hemangioma, and vascular splenic pathology like splenic infarction, splenic abscess, and splenic laceration.

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“…Hämolytische Anämien wie die Sphärozytose sind gewöhnlich durch eine leichte Splenomegalie gekennzeichnet. Lediglich die homozygote Sichelzellanämie zeigt als einzige hämolytische Anämie obligat eine kleine Milz (Hyposplenie), bedingt durch rezidivierende Milzinfarkte mit konsekutiver funktioneller Asplenie [20,21].…”

Section: Sonografie Bei Weiteren Erkrankungen Des Blutbildesunclassified

“…Die Echomorphologie der karzinomatösen Herdbildung ist variabel [71]. diagnostische/therapeutische Splenektomie kommt grundsätzlich selten, aber vorwiegend bei Milzlazeration, intralienalen Pseudoaneurysmata und großen malignitätssuspekten Herdbildungen zum Einsatz [20,21]…”

Section: Milzherde Bei Lymphomen/bei Metastasenunclassified

Stellenwert der Abdomensonografie in der Hämatologie

et al. 2018

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At the time of primary diagnosis, hematological diseases often present with unspecific symptoms, and abdominal sonography is performed as part of the initial diagnostic work-up. The detection of an enlarged spleen, of pathological lymph nodes or of other findings may help to suspect hematological diseases. Also, in case of suspected lymph node enlargement, sonography may be a first step. If detection of enlarged and pathological lymph nodes leads to suspicion of malignant lymphomas, examination of further lymph node stations may give an initial impression of the stage of disease and can help in planning further diagnostic strategies. Due to its wide availability, the feasibility of bedside examination, lack of radiation exposure and easy repeatability, sonographic examinations may also play an important role in the initial work-up of anemia, leucopenia, leukocytosis, and thrombopenia as well as for the detection of complications when following up on hematological diseases.

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The small spleen: Sonographic patterns of functional hyposplenia or asplenia

Cited by 27 publications

References 10 publications

The absent and vanishing spleen: Congenital asplenia and hyposplenism-two case reports

The absent and vanishing spleen: Congenital asplenia and hyposplenism-two case reports

Contrast Enhanced Sonography for Diagnosis of (Peri-) Splenic Pathology

Stellenwert der Abdomensonografie in der Hämatologie

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