Abstract:Background This study aimed to evaluate the potential neuroprotective
effect of cyclosporine – a calcineurin inhibitor–, ondansetron,
and tropisetron-5-hydroxytryptamine (serotonin) 3 receptor (5-HT3R)
antagonists–, on optic nerve crush (ONC) injury in rats. Moreover,
underlying signaling activities of their beneficial neuroprotective effects were
studied.
Methods Adult male rats were treated with the … Show more
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