2020
DOI: 10.1590/s2175-97902019000418551
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The plasma Tumor Necrosis Factor-α (TNF-α) does not have any correlation with disease activity in rheumatoid arthritis patients treated with disease modifying anti-rheumatic drugs (DMARDs)

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Cited by 2 publications
(4 citation statements)
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“…Patients with a low disease activity score had a significantly lower concentration of serum TNF-α than in the subgroups with moderate and high disease activity. Similar to our findings were the observations made by other studies conducted on newly diagnosed RA patients [ 5 , 7 , 19 ]. These findings show that TNF-α is expressed earlier in the pathologic events in DMARD naïve RA patients and can therefore be an important marker for the evaluation of disease activity.…”
Section: Discussionsupporting
confidence: 93%
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“…Patients with a low disease activity score had a significantly lower concentration of serum TNF-α than in the subgroups with moderate and high disease activity. Similar to our findings were the observations made by other studies conducted on newly diagnosed RA patients [ 5 , 7 , 19 ]. These findings show that TNF-α is expressed earlier in the pathologic events in DMARD naïve RA patients and can therefore be an important marker for the evaluation of disease activity.…”
Section: Discussionsupporting
confidence: 93%
“…Serum TNF-α was shown to have a positive correlation with DAS28 in our study participants. Previous studies also showed a positive correlation between plasma levels of TNF-α and activity of the disease in the newly diagnosed RA patients and not in patients who were on DMARD treatment [ 7 , 19 ]. Shrivastava et al and others reported that DAS28 scores showed a significant correlation with serum TNF-α in the high disease activity subgroup of RA patients [ 7 , 23 , 24 ].…”
Section: Discussionmentioning
confidence: 98%
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