The pivotal role of small non-coding RNAs in the regulation of seed development

Rodrigues, Andreia S.; Miguel, Celia María Gonzalo

doi:10.1007/s00299-017-2120-5

Cited by 24 publications

(23 citation statements)

References 108 publications

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“…Previous work documented that FUS3 was able to induce genes involved in the production of MIR156 directly (Wang and Perry, 2013). MIR156 is involved in preventing precocious maturation (Rodrigues and Miguel, 2017) and, after completion of germination, other developmental phase changes that are related to FUS3 (Lumba et al ., 2012). We proposed that FUS3, which appears to induce only direct target genes, is involved in indirect repression of the MIR156 targets SPL10 and SPL11 via MIR156 to prevent premature activation of maturation genes during seed development as well as documented phase transitions that occur in the fus3 loss‐of‐function (Nodine and Bartel, 2010; Willmann et al ., 2011; Lumba et al ., 2012).…”

Section: Resultsmentioning

confidence: 99%

Direct and indirect targets of the arabidopsis seed transcription factor ABSCISIC ACID INSENSITIVE3

et al. 2020

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SUMMARY Arabidopsis thaliana ABSCISIC ACID INSENSITIVE3 (ABI3) is a transcription factor in the B3 domain family. ABI3, along with B3 domain transcription factors LEAFY COTYLEDON2 (LEC2) and FUSCA3 (FUS3), and LEC1, a subunit of the CCAAT box‐binding complex, form the so‐called LAFL network to control various aspects of seed development and maturation. ABI3 also contributes to the abscisic acid (ABA) response. We report on chromatin immunoprecipitation‐tiling array experiments to map binding sites for ABI3 globally. We also assessed transcriptomes in response to ABI3 by comparing developing abi3‐5 and wild‐type seeds and combined this information to ascertain direct and indirect responsive ABI3 target genes. ABI3 can induce and repress its transcription of target genes directly and some intriguing differences exist in cis motifs between these groups of genes. Directly regulated targets reflect the role of ABI3 in seed maturation, desiccation tolerance, entry into a quiescent state and longevity. Interestingly, ABI3 directly represses a gene encoding a microRNA (MIR160B) that targets AUXIN RESPONSE FACTOR (ARF)10 and ARF16 that are involved in establishment of dormancy. In addition, ABI3, like FUS3, regulates genes encoding MIR156 but while FUS3 only induces genes encoding this product, ABI3 induces these genes during the early stages of seed development, but represses these genes during late development. The interplay between ABI3, the other LAFL genes, and the VP1/ABI3‐LIKE (VAL) genes, which are involved in the transition to seedling development are examined and reveal complex interactions controlling development.

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Section: Resultsmentioning

confidence: 99%

Direct and indirect targets of the arabidopsis seed transcription factor ABSCISIC ACID INSENSITIVE3

et al. 2020

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“…In Pinus taeda [ 15 ] and Brassica napus [ 28 ], miRNAs were identified from zygotic embryos at late developmental stages. More and more researchers have provided abundant evidences that miRNAs are required for the majority of embryonic cell differentiation and development in Arabidopsis [ 29 , 30 ]. In chrysanthemum cross breeding, embryonic development is a crucial stage for seed formation, but embryo abortion is prevalent in chrysanthemum distant hybridization [ 31 , 32 ].…”

Section: Discussionmentioning

confidence: 99%

MicroRNA and Putative Target Discoveries in Chrysanthemum Polyploidy Breeding

Zhang

Zhao

et al. 2017

International Journal of Genomics

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MicroRNAs (miRNAs), around 22 nucleotides (nt) in length, are a class of endogenous and noncoding RNA molecule that play an essential role in plant development, either by suppressing the transcription of target genes at a transcriptional level or inhibiting translation at a posttranscriptional level. To understand the roles of miRNAs and their target genes in chrysanthemum polyploidy breeding, three sRNA libraries of normal and abnormal embryos after hybridization were performed by RNA-Seq. As a result, a total of 170 miRNAs were identified and there are 41 special miRNAs in cross of paternal chromosome doubling, such as miR169b, miR440, and miR528-5p. miR164c and miR159a were highly expressed in a normal embryo at 18 days after pollination, suggesting the regulatory role at the late stage of embryonic development. miR172c was only detected in the normal embryo at 18 days after pollination, which means that miR172c mainly mediates gene expression in postembryonic development and these genes may promote embryo maturation. Other miRNAs, including miR414, miR2661, and miR5021, may regulate the genes participated in pathways of auxin response and energy metabolism; then they regulate the complex embryonic development together.

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“…Overall, miRNA are involved in the control of several aspects of plant development, including seed and embryo development (for review see Seefried et al, 2014;D'Ario et al, 2017;Rodrigues and Miguel, 2017). For instance, loss of DICER-LIKE 1 (DCL1), the major RNA helicase involved in miRNA processing leads to embryo lethality (Golden et al, 2002;Park et al, 2002).…”

Section: Post-transcriptional and Post-translational Regulationsmentioning

confidence: 99%

Molecular and epigenetic regulations and functions of the LAFL transcriptional regulators that control seed development

et al. 2018

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The LAFL (i.e. LEC1, ABI3, FUS3, and LEC2) master transcriptional regulators interact to form different complexes that induce embryo development and maturation, and inhibit seed germination and vegetative growth in Arabidopsis. Orthologous genes involved in similar regulatory processes have been described in various angiosperms including important crop species. Consistent with a prominent role of the LAFL regulators in triggering and maintaining embryonic cell fate, their expression appears finely tuned in different tissues during seed development and tightly repressed in vegetative tissues by a surprisingly high number of genetic and epigenetic factors. Partial functional redundancies and intricate feedback regulations of the LAFL have hampered the elucidation of the underpinning molecular mechanisms. Nevertheless, genetic, genomic, cellular, molecular, and biochemical analyses implemented during the last years have greatly improved our knowledge of the LALF network. Here we summarize and discuss recent progress, together with current issues required to gain a comprehensive insight into the network, including the emerging function of LEC1 and possibly LEC2 as pioneer transcription factors.

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The pivotal role of small non-coding RNAs in the regulation of seed development

Cited by 24 publications

References 108 publications

Direct and indirect targets of the arabidopsis seed transcription factor ABSCISIC ACID INSENSITIVE3

Direct and indirect targets of the arabidopsis seed transcription factor ABSCISIC ACID INSENSITIVE3

MicroRNA and Putative Target Discoveries in Chrysanthemum Polyploidy Breeding

Molecular and epigenetic regulations and functions of the LAFL transcriptional regulators that control seed development

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