The Pigeon Pea (Cajanus cajan Millsp.), A High-protein, Tropical Bush Legume1

Morton, Julia F.

doi:10.21273/hortsci.11.1.11

Cited by 37 publications

(1 citation statement)

References 14 publications

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“…1 In these countries, the seeds of the shrub, which are very rich in proteins, carbohydrates, minerals, vitamins and essential amino acids, are processed into meal or consumed as a whole, whereas the leaves are eaten fresh in salads or as a streamed or blanched vegetable. [2][3][4] For example, in India, Cajanus cajan is primarily consumed as so called dhal (decorticated split cotyledons). 1 Besides its importance in nutrition, the plant is very popular in traditional medicine, where it is used as an infusion or tea preparation against various skin diseases, including bedsores, oral ulcers and measles, as well as urinary tract infections, menstrual disorders, genital irritations, hepatitis, diabetes, dysentery etc.…”

Section: Introductionmentioning

confidence: 99%

Cajanus cajan – a source of PPARγ activators leading to anti-inflammatory and cytotoxic effects

et al. 2016

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Cajanus cajan is an important legume crop in the human diet in many parts of the world. Due to its pharmacological properties, C. cajan is, moreover, used in traditional medicine for treating skin diseases, diabetes, inflammatory disorders and various other dysfunctions. In this study, we focused on the role of peroxisome proliferator-activated receptor gamma (PPARγ) as a potential therapeutic target of Cajanus cajan and its main compounds for the treatment of cancer, inflammation and inflammation-related disorders. The anti-inflammatory potential of C. cajan and its bioactive compounds and their cytotoxicity on the human cervical adenocarcinoma cell line HeLa, the human colorectal adenocarcinoma cell line CaCo-2 and the human breast adenocarcinoma cell line MCF-7 were elucidated. C. cajan and its compounds exerted significant anti-inflammatory activity on lipopolysaccharide-stimulated macrophages, showed good cytotoxic effects on the 3 different cancer cell lines and proved PPARγ activity in vitro. The main active compounds were orientin, pinostrobin and vitexin. Cajaninstilbene acid and pinosylvin monomethylether were identified as novel PPARγ activators. Based on these data, C. cajan provides excellent beneficial medicinal attributes and may be used as a potential food or a pharmaceutical supplement.

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Section: Introductionmentioning

confidence: 99%

Cajanus cajan – a source of PPARγ activators leading to anti-inflammatory and cytotoxic effects

et al. 2016

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Pigeonpea

Sharma

Bhatnagar‐Mathur

Saxena

et al. 2008

Compendium of Transgenic Crop Plants

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Pigeonpea is one of the major grain legumes grown in the tropics and subtropics of the world that forms a significant component of the diet due to its high protein content. Most of the differences in potential and realized yields in pigeonpea have been attributed to several biotic and abiotic constraints; besides the low productivity potential of marginal lands, where this crop is commonly grown. Of the various constraints limiting pigeonpea production, insect pests cause substantial damages. Conventional breeding efforts in pigeonpea crop improvement have been successful in producing improved seed quality and reduction of crop maturity duration. Nevertheless, genetic improvement of pigeonpea has been restricted due to the nonavailability of better genetic resources and strong sexual barriers between the cultivated and wild species. The recent developments in plant genetic engineering have provided immense potential in overcoming some of these constraints, thereby, offering opportunities for its successful integration with conventional crop improvement strategies. This chapter describes the pigeonpea crop, various constraints to its productivity, recent developments in its breeding, and emerging transgenic innovations that could play a significant role in the improvement of pigeonpea crop. We also highlight the current status of pigeonpea transgenics and related biosafety and IPR issues for the successful application of this technology in the near future.

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The kinetics of reversal of pre‐sickled erythrocytes by the aqueous extract of Cajanus cajan seeds

Onah

Akubue

Okide

2002

Phytotherapy Research

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The aqueous methanol extract (3:1, v/v) of the seeds of Cajanus cajan was investigated for antisickling properties. The extract possessed significant antisickling activity and was found to be concentration-dependent. The kinetics of reversal of presickled erythrocyte (HbSS) cells using the extract at 0.5 mg/mL, 1.0 mg/mL, 1.5 mg/mL, 2.0 mg/mL and 2.5 mg/mL showed first-order kinetics with rate constants of 5.833 x 10(-3) min(-1), 6.143 x 10(-3) min(-1), 5.957 x 10(-3) min(-1) 6.00 x 10(-3) min(-1) and 6.046 x 10(-3) min(-1), respectively, and with an average half-life 115.6 min. Phytochemical screening of the extract revealed the presence of free amino acids, phenolic compounds, tannins, globulins and saponins. These results show that the extract has potential use in the management of painful episodes experienced by sickle cell patients.

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The Pigeon Pea (Cajanus cajan Millsp.), A High-protein, Tropical Bush Legume1

Cited by 37 publications

References 14 publications

Cajanus cajan – a source of PPARγ activators leading to anti-inflammatory and cytotoxic effects

Cajanus cajan – a source of PPARγ activators leading to anti-inflammatory and cytotoxic effects

Pigeonpea

The kinetics of reversal of pre‐sickled erythrocytes by the aqueous extract of Cajanus cajan seeds

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