The Phenomenon of Irritable Skin in Atopic Eczema

Influence of short‐term exposure to airborne Der p 1 and volatile organic compounds on skin barrier function and dermal blood flow in patients with atopic eczema and healthy individuals

“…In our study, both the TEWL and skin blood flow were significantly increased 48 h after exposure, but not at the other timepoints investigated. This effect is biologically plausible as epidermal changes need time to develop, similar to the eczematous reaction in atopic eczema following skin provocation with allergens or irritants [42]. Other than in immediate‐type allergy, aerogenous allergen exposure in real life usually results in disease exacerbation after days.…”