The Pharmacological Actions of Some Contrast Media and a Comparison of their Merits

Blood pressure and heart rate responses in carotid angiography with sodium acetrizoate (Triurol)

“…Similar results were reported by WEATHERALL (1942) with Diodone and Iodoxyl in cats, BROMAN and OLSSON (1948) with various diodone contrast media in rabbits, SCHMIDT (1955) The aim of the present investigation was to study experimentally the mechanism of these effects on the circulatory apparatus in carotid angiography. For this purpose we chose sodium acetrizoate (Triurol), the contrast medium that GREITZ employed and which, according to LIND-GREN, has significant effects.…”

Blood Pressure and Heart Rate Responses in Carotid Angiography with Sodium Acetrizoate (Triurol): An Experimental Study in Cats

“…Similar results were reported by WEATHERALL (1942) with Diodone and Iodoxyl in cats, BROM AN and OLSSON (1948) with various diodone contrast media in rabbits, SCHMIDT (1955) with Thorotrast, Perabrodil, Ioduron, Umbradil and Urografin in cats and rabbits, KLINGLER BLOOD PRESSURE AND HEART RATE RESPONSES IN CAROTID ANGIOGRAPHY 161 et coll. (1956) with Ioduron and Diodone in man, dogs, cats, and rats, and PEDACHENKO (1957) with Cardiotrast in dogs and rabbits.…”

Untoward reactions to radiodiagnostic contrast media

“…The year 1942 saw the first comprehensive survey of reactions to contrast media on organ systems in the experimental animal with reference to human reactions. 45 Since then many case reports of reactions to the various agents and techniques have appeared. As a result, the incidence and severity of reactions probably has been lessened by pretesting and the taking of a history for allergic responses.…”

“…28 Benzene derivatives introduced into the above-listed preparations produced only occasional dropped beats. 45 The action of organic iodides on blood vessels has been studied on the rabbit ear 10 or the dog hind-leg preparation. 25 Iodopyracet (Diodrast) and iodomethamate (iodoxyl) cause dilatation of ear vessels, but inital constriction of hind-leg vessels was followed by more prolonged dilatation.…”