“…Recent chemical and pharmaceutical investigations on this species have demonstrated that taccalonolides A and E were the first natural steroids to show microtubule-stabilising activity (Tinley et al, 2003). Besides taccalonolides A and E, 11 other highly oxygenated taccalonolides have been isolated from this species (Z. Chen, Wang, & M. Chen, 1987;Chen, Wang, & Shen, 1988;Shen, Chen, & Gao, 1991, 1996Shen, Chen, Gao, & Wichtl, 1997). Our previous chemical investigation of this plant led to the isolation of four new steroidal saponins; five new withanolides, plantagiolides A-E and three new taccalonolides (Liu & Chen, 2002;Liu, Ni, Hao, & Chen, 2006;Yang et al, 2008).…”