The pattern of osteocyte in dental socket bone regenerative induced by hydroxyapatite bovine tooth graft

Zubaidah, Nanik; Kunarti, Sri; Febrianti, Nadira Nurin; Nurdianto, Arif Rahman; Oktaria, Wanda; Luthfi, Muhammad

doi:10.15562/bmj.v11i3.3844

Cited by 2 publications

(3 citation statements)

References 21 publications

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“…32 The normal wound healing process will increase the thickness of collagen when entering the proliferative phase and release growth factors to stimulate the proliferative activity of osteoblast cells, which in turn will induce osteocyte cells in wound healing. 33,31 In this study, the BAM application group had higher collagen thickness, number of osteoblasts, and osteocytes compared to the control group. This is because BAM, in the form of a sponge, contains collagen, which can absorb blood, so that bleeding wounds stop more quickly and speed up the haemostasis and coagulation phases.…”

Section: Discussionmentioning

confidence: 56%

“…This is indicated by the fact that the number of osteocyte cells has increased compared to osteoblast cells. 15 Zubaidah et al 31 , stated that osteocytes also showed that osteocytes started to grow on the 14 th day after the evaluation, and they kept growing for another 28 days following the application of hydroxyapatite bovine tooth graft and PEG as the carrier. Thus, osteoblast and osteocytes as components of bone regeneration are also inducing bone healing.…”

Section: Discussionmentioning

confidence: 99%

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The Effect of Application Bovine Amniotic Membrane on Osteoblasts, Osteocytes, and Collagen

Wibowo,

Octarina,

Munadziroh

et al. 2023

Padjadjaran J Dent

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Introduction: Tooth extraction can result in loss of alveolar bone. The application of biomaterials Bovine Amniotic Membrane (BAM) that containing growth factors and collagen is expected to play a role in socket preservation. This study aimed to observe the effect of BAM application on the growth of osteoblasts, osteocytes, and collagen in histological preparate of the alveolar bone socket of Sprague Dawley rats (SD). Methods: 16 male SD rats were used in this group. SD rats were extracted on the mandible central incisivus. Afterward, it was divided into two groups, specifically the control group (without treatment) and the treatment group (BAM application). After extraction, the treatment group was applied with BAM with a size of 1.5 mm x 10 mm in socket alveolar bone. On the 14th and 28th day, the rats were euthanized and the alveolar bone socket of mandibular tissue was taken and stained with Hematoxylin Eosin (HE) and Masson Trichrome (MT). Results: The results of all groups showed that the number of osteoblasts and collagen thickness was higher on day 14th compared to day 28th, while osteocytes continued to increase from day 14th to 28th. The thickness of collagen, osteoblasts, and osteocytes in groups with BAM application was higher than without application. Statistical results showed that there were significant differences between groups (p<0.05). Conclusion: The application of BAM can act as material preservation socket. This biomaterial can accelerate recovery by increasing collagen thickness, osteoblasts, and osteocytes.

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Section: Discussionmentioning

confidence: 56%

Section: Discussionmentioning

confidence: 99%

The Effect of Application Bovine Amniotic Membrane on Osteoblasts, Osteocytes, and Collagen

Wibowo,

Octarina,

Munadziroh

et al. 2023

Padjadjaran J Dent

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“… 12 13 14 15 Bovine-based HA is among the most applied bone grafts besides sintered HA due to their biocompatibility and osteoconductivity. 16 17 18 19 The main drawback of bovine HA and sintered HA is their slow resorption during implantation. This study attempted to fabricate nonsintered HA to improve resorption.…”

Section: Discussionmentioning

confidence: 99%

Compressive Strength of Newly Developed Nonsintered Hydroxyapatite Blocks for Bone Graft Applications

Sunarso,

Suryadi,

Indrani

et al. 2023

Eur J Dent

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Objective This study aimed to fabricate and evaluate the phase purity and compressive strength of the nonsintered hydroxyapatite (HA) block obtained via phase transformation of set calcium sulfate dihydrate (CSD) block under hydrothermal conditions at different temperatures. Materials and Methods Nonsintered HA block was prepared by immersion CSD block (4 mm in diameter and 8 mm in height) in a 1 mol/L sodium phosphate (Na3PO4) solution under hydrothermal conditions at 100°C, 140°C, and 180°C for 48 hours. X-ray diffraction was used to determine the crystalline phase of the obtained blocks. The mechanical strength of the blocks was measured using a compressive strength test. Results The result shows that the CSD block could be fully transformed into a HA block at 180°C for 48 hours without changing its macroscopic shape. The compressive strength of the obtained blocks was lower compared with the CSD block. Conclusion The current method has successfully produced a nonsintered HA block at 180°C for 48 hours. The compressive strength of the HA block decreased compared with the gypsum block used as a precursor. However, the compressive strength of the HA block that was produced still falls within the range of cancellous bone.

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The pattern of osteocyte in dental socket bone regenerative induced by hydroxyapatite bovine tooth graft

Cited by 2 publications

References 21 publications

The Effect of Application Bovine Amniotic Membrane on Osteoblasts, Osteocytes, and Collagen

The Effect of Application Bovine Amniotic Membrane on Osteoblasts, Osteocytes, and Collagen

Compressive Strength of Newly Developed Nonsintered Hydroxyapatite Blocks for Bone Graft Applications

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