The pathology of visible blood vessels on the nasal septum in children with epistaxis

Montague, Mary‐Louise; Whymark, Andrew; Howatson, Allan G.; Kubba, Haytham

doi:10.1016/j.ijporl.2011.05.011

Cited by 23 publications

(18 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They also reported that digital trauma cause septal neovascularization in children with recurrent epistaxis. 19 However this theory is not supported in our study.…”

Section: Discussioncontrasting

confidence: 91%

“…Mean platelet volume measurement is affected by the type of anticoagulant (EDTA or citrate), time interval between blood sampling and MPV analysis, and the temperature at which MPV is measured, MPV increases over time in EDTA tube and it is accepted that platelet swelling in EDTA tubes can be minimized by analyzing the samples within less than 1 hour. [17][18][19][20] In our hospital CBC measurements are performed at room temperature and in EDTA tubes. The time interval between blood sampling and CBC analysis was calculated from the software program and it was within acceptable bounds (18.6±8.1 minutes for patients and 17.1±8 minutes for control group).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Complete Blood Count Parameters in Recurrent Pediatric Idiopathic Epistaxis

Akdoğan¹,

Tanrikulu²,

Babakurban³

et al. 2019

KBB ve BBC Dergisi

View full text Add to dashboard Cite

A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : The aim of this study was to investigate the relationship between complete blood cell count (CBC) parameters and pediatric recurrent idiopathic epistaxis. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : The patient records of the children with epistaxis were retrospectively analyzed. The records of the patients with recurrent idiopathic epistaxis were included. Compete blood count results of the patients at of least two visits for epistaxis were retrieved from the hospital records. Mean platelet volume (MPV), red blood cell distribution width (RDW), platelet, hemoglobin, hematocrit, lympocyte, leucocyte, neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) levels of these patients were compared with age-matched and gender-matched controls. R Re es su ul lt ts s: : A total of 153 patients had at least two visits with epistaxis and 107 of these were diagnosed with recurrent idiopathic epistaxis patients. There was no statistical difference in terms of age and gender between the groups. MPV, RDW, lympocyte levels were higher and platelet, hemoglobin, hematocrit, leucocyte, NLR and PLR levels were lower in recurrent idiopathic epistaxis patients. No statistically significant difference was detected between the groups according to the permutational non-parametric MANOVA (p>0.05). C Co on nc cl lu us si io on n: : Complete blood count is one of the most common laboratory test for evaluation of epistaxis in children. Although MPV, RDW, NLR and PLR are easily measured as a part of the CBC, their importance in epistaxis is not adequately presented. MPV, RDW, NLR and PLR have been identified as markers of inflammation and associated with an ample amount of diseases. However in this study we have concluded that there was no association between CBC parameters and recurrent pediatric idiopathic epistaxis. K Ke ey yw wo or rd ds s: : Epistaxis; children; complete blood cell count; mean platelet volume Ö ÖZ ZE ET T A Am ma aç ç: : Bu çalışmanın amacı, tam kan sayımı (TKS) parametreleri ile pediatrik rekürren idiyopatik epistaksis arasındaki ilişkiyi araştırmaktır. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Epistaksisi olan çocukların hasta kayıtları retrospektif olarak incelendi. Rekürren idiyopatik epistaksisi olan hastalar çalışmaya dahil edildi. En az iki kez burun kanaması nedeniyle başvuran hastaların TKS sonuçları, hastane kayıtlarından elde edildi. Bu hastaların ortalama trombosit hacmi (OTH), eritrosit dağılım genişliği (EDG), trombosit, hemoglobin, hematokrit, lenfosit, lökosit, nötrofil/lenfosit oranı (NLO) ve trombosit/lenfosit oranı (TLO) düzeyleri benzer yaş ve cinsiyetteki sağlıklı bireylerle karşılaştırıldı. B Bu ul lg gu ul la ar r: : Toplamda 153 hastanın epistaksis tanısı ile birden fazla başvurusu vardı. Bunlardan 107'si rekürren idiyopatik epistaksis tanısı almıştı. Gruplar arasında yaş ve cinsiyet açısından istatistiksel fark yoktu. Rekürren idiyopatik epistaksis hastalarında OTH, EDG, lenfosit düzeyleri y...

show abstract

“…They also reported that digital trauma cause septal neovascularization in children with recurrent epistaxis. 19 However this theory is not supported in our study.…”

Section: Discussioncontrasting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Complete Blood Count Parameters in Recurrent Pediatric Idiopathic Epistaxis

Akdoğan¹,

Tanrikulu²,

Babakurban³

et al. 2019

KBB ve BBC Dergisi

View full text Add to dashboard Cite

show abstract

“…It has been shown that children with recurrent epistaxis are more likely to have nasal colonization with Staphylococcus aureus than controls (5). Also, it has been postulated that low-grade inflammation may cause irritation, crusting and digital trauma coupled with increased vascularity due to inflammation and trauma from the separation of crusts (6). Further evidence supporting this comes from controlled trials showing benefit from antiseptic cream but not from petroleum jelly/vaseline for recurrent pediatric epistaxis (7,8).…”

mentioning

confidence: 99%

Nasal Bacterial Colonization in Pediatric Epistaxis: The Role of Topical Antibacterial Treatment

et al. 2016

View full text Add to dashboard Cite

Background: Epistaxis is a common problem in childhood. It has been shown that children with recurrent epistaxis are more likely to have nasal colonization with Staphylococcus aureus. It has been suggested that lowgrade inflammation, crusting and increased vascularity due to bacterial colonization contributes to the development of epistaxis in children. Aims: This study aimed to investigate the nasal colonization and treatment outcome in pediatric epistaxis patients. Study Design: Retrospective cross-sectional study. Methods: Charts of the pediatric patients referred to our university hospital otolaryngology outpatient clinics for the evaluation of epistaxis were reviewed. The patients whose nasal cultures had been taken at the first clinical visit comprised the study group. Results: Staphylococcus aureus was the most common bacteria grown. The presence of crusting and hypervascularity was not dependent on the type of bacterial growth and there was no relation between hypervascularity and crusting of the nasal mucosa. Thirty-six patients were evaluated for the outcome analysis. Resolution of bleeding was not dependent on nasal colonization; in patients with colonization, there was no difference between topical antibacterial and non-antibacterial treatments. Conclusion: Despite the high colonization rates, topical antibacterial treatment was not found superior to nonantibacterial treatment. Our study does not support the belief that bacterial colonization results in hypervascularity of the septal mucosa causing epistaxis since no relation was found between nasal colonization, hypervascularity and crusting. The role of bacterial colonization in pediatric epistaxis need to be further investigated and treatment protocols must be determined accordingly.

show abstract

“…After biopsies of the nasal septal mucosa were taken from five children with recurrent epistaxis undergoing nasal cautery, Montague et al found prominent thin-walled arterioles and capillaries with a surrounding inflammatory infiltrate, with no evidence of venous varicosities or arterial microaneurysms. They postulated a mechanism for septal neovascularisation due to chronic low-grade inflammation, as a cause for recurrent epistaxis in children 12. Of note is that four of the seven of our patients had prominent vessels of the nasal septum.…”

Section: Discussionmentioning

confidence: 49%

The therapeutic efficacy of propranolol in children with recurrent primary epistaxis

Bjelaković¹,

Bojanović²,

Lukic³

et al. 2013

DDDT

View full text Add to dashboard Cite

We hypothesized that some characteristics of beta-blockers, including negative inotropic, peripheral vasoconstrictor, and antiangiogenic effects, might be potentially useful in treating children with epistaxis. From June 2010 to March 2012, a total of seven children with recurrent primary epistaxis resistant to conventional management were observed at our institution. An overall effectiveness of propranolol was noted in all seven children when given a dose of 1.5–2 mg/kg/day (divided into three doses) as a second line therapy for terminating epistaxis. Based on our first experience, we believe that propranolol could be a favorable treatment option for patients with primary epistaxis.

show abstract

The pathology of visible blood vessels on the nasal septum in children with epistaxis

Cited by 23 publications

References 8 publications

Complete Blood Count Parameters in Recurrent Pediatric Idiopathic Epistaxis

Complete Blood Count Parameters in Recurrent Pediatric Idiopathic Epistaxis

Nasal Bacterial Colonization in Pediatric Epistaxis: The Role of Topical Antibacterial Treatment

The therapeutic efficacy of propranolol in children with recurrent primary epistaxis

Contact Info

Product

Resources

About