The pathology of a spontaneous and experimental mucosal disease-like syndrome in sheep recovered from clinical Border disease

Barlow, R.M.; Gardiner, A.C.; Nettleton, P. F.

doi:10.1016/0021-9975(83)90032-4

Cited by 33 publications

(20 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…No classical symptoms (abortion, stillbirth and the birth of small, weak lambs) were observed in tested goat herds; only diarrhea and alimentary tract lesions were the major clinical and pathologic signs. Barlow et al, Monies et al and Chalmers et al have reported that BDV caused mucosal disease-like lesions in sheep, which was characterized by unremitting diarrhea [4,5,13]. Few studies have done for BDV infection in goat herds [14-16]; and no diarrhea related report was available.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Detection of border disease virus (BDV) in goat herds suffering diarrhea in eastern China

Zhao

et al. 2013

Virol J

View full text Add to dashboard Cite

BackgroundBorder disease virus (BDV) is an important pathogen in sheep and goat production. Neither epidemiological investigation nor any reports of BDV infection was available in China. During Jan to Apr, 2012, several herd goats in Anhui and Jiangsu provinces in eastern China suffered unremitting diarrhea, with morbidity and mortality of about 28-37% and 10-15%, respectively. In the present study, sera and tissue samples from diseased goats of four farms were taken for BDV detection, isolation and identification.ResultsPanpesti generic primers and border disease virus (BDV)-specific primers targeting the 5’-UTR region produced RT-PCR positive bands for sera (24/28) and tissue samples (7/30). Twenty positive sera and tissue samples were inoculated onto Madin-Darby bovine kidney (MDBK) cells for virus isolation. Finally, three different strains of BDV, named AH12-01, AH12-02 and JS12/04, were successfully isolated as identified by RT-PCR using 5’-UTR and Npro gene primers, sequencing and electron microscopy. Sequences of 5’-UTR and Npro genes of them were used for phylogenetic analysis and comparison to other reference sequences available in GenBank. The results indicated AH12-01, AH12-02 and JS12/04 possess high relationship with the BDV 3 group viruses and differed with each other.ConclusionThis is the first detection of BDV from goats with diarrhea and confirmation of BDV infection in China.

show abstract

Section: Discussionmentioning

confidence: 99%

“…BDV belongs to the genus Pestivirus of the family Flaviviridae , together with bovine virus diarrhea viruses 1 and 2 (BVDV 1, 2) and classical swine fever virus (CSFV) [2,3]. In some reported cases, BDV also caused mucosal disease-like lesions in sheep [4,5]. …”

Section: Introductionmentioning

confidence: 99%

Detection of border disease virus (BDV) in goat herds suffering diarrhea in eastern China

Zhao

et al. 2013

Virol J

View full text Add to dashboard Cite

show abstract

“…The clinical disease is usually manifested by barren ewes, abortion, and stillbirths. occasionally enteric dysfunction (BARLOW et al, 1983, NETTLETON & ENTRICAN 1995, MONIES & SIMPSON 1997, RADOSTITS et al, 2000.…”

Section: Cerebelo Associada Com Diminuição Da Densidade De Células E mentioning

confidence: 99%

Neurological disorder associated with pestivirus infection in sheep in Rio Grande do Sul, Brazil

et al. 2004

View full text Add to dashboard Cite

show abstract

“…4 Apart from cattle, a MD-like syndrome has been reported 11 and experimentally reproduced in sheep. 2 Worldwide evidence for BVDV infections of free-ranging and captive wild ruminants includes multiple serologic surveys and several virus isolations. Outbreaks of disease with similarities to MD have been described in different ruminant species, 16 but they all lack diagnostic confirmation.…”

Section: Brief Communicationmentioning

confidence: 99%

Experimental Superinfection of a Lesser Malayan Mousedeer (Tragulus javanicus) Persistently Infected with Bovine Viral Diarrhea Virus

Semrau¹,

Wibbelt²,

Hilbe³

et al. 2008

Journal of Zoo and Wildlife Medicine

View full text Add to dashboard Cite

The pathology of a spontaneous and experimental mucosal disease-like syndrome in sheep recovered from clinical Border disease

Cited by 33 publications

References 12 publications

Detection of border disease virus (BDV) in goat herds suffering diarrhea in eastern China

Detection of border disease virus (BDV) in goat herds suffering diarrhea in eastern China

Neurological disorder associated with pestivirus infection in sheep in Rio Grande do Sul, Brazil

Experimental Superinfection of a Lesser Malayan Mousedeer (Tragulus javanicus) Persistently Infected with Bovine Viral Diarrhea Virus

Contact Info

Product

Resources

About