The Passive Transfer of Chemical Hypersensitivities in Rabbits

Treatment of Infectious and Neoplastic Diseases with Transfer Factor

“…The cell-free supernatants contained an agent which upon injection into nonsensitized guinea pigs, rendered them re sponsive to skin tests with the antigen. Recently, this phenomenon has re ceived further study by Burger et al [14][15][16]. In addition to confirming J eter's original observation [36], Burger et al [16] reported that the active component in the supernatant fluids was dialyzable and could not be remov ed by an immuno-absorbant that was specific for dinitrophenyl groups, thereby reducing the likelihood that antigen was the component responsible for sensitization.…”

“…In addition to confirming J eter's original observation [36], Burger et al [16] reported that the active component in the supernatant fluids was dialyzable and could not be remov ed by an immuno-absorbant that was specific for dinitrophenyl groups, thereby reducing the likelihood that antigen was the component responsible for sensitization. Burger et al [15] have recently adapted the basic technique to passive transfer of contact allergy and tuberculin sensitivity to rabbits. The Jeter-Burger animal model of passive transfer of contact allergy has not yet been confirmed.…”