The Parliamentary Dimension of the Crimean War

Abstract

The central issue in most wars is how to win. The central issue in the Crimean War was whether there should be a war. Throughout most of the war, the question of peace or war remained an open one, dependent on military prospects, diplomatic vicissitudes, and the shuttlecock of parliamentary faction. That British public opinion was hotly for war was interpreted by players of the parliamentary game only as meaning that it might become pacific with equal volatility. The supposed political invincibility of Palmerston in 1855–6 had some reality outside Parliament, but little inside Parliament where it mattered. If events in Parliament varied in line with the war, it was also true that parliamentary prospects could affect the war.

Identification of aspirinase with one of the carboxylesterases requiring a thiol group

“…The hydrolysis of aspirin (acetylsalicylic acid) to salicylic acid as part of its metabolism has been recognized for a long time, but little has been done to characterize the enzyme or enzymes responsible. Liver homogenate is known to have a significant ability to hydrolyse aspirin in the guinea pig, especially when compared with serum or plasma (Vincent & Lagreu, 1949). Aspirin hydrolysis by mammalian tissues and plasma has been attributed to 'acetylesterases', distinguishable from cholinesterases by inhibition properties (Morgan & Truitt, 1965).…”