The oxygen uptake kinetic response to moderate intensity exercise in overweight and non-overweight children

Potter, Christopher R.; Zakrzewski, Julia; Draper, Stephen B.; Unnithan, V. B.

doi:10.1038/ijo.2012.130

Cited by 8 publications

(12 citation statements)

References 34 publications

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“…Childhood obesity also contributes to severe cardiorespiratory deconditioning, leading to limitations in motor activity, physical functioning, and exercise tolerance, and consequentially resulting in a poorer quality of life (Gidding et al 2004). This deconditioning has recently been shown to be manifest in the dynamic pulmonary oxygen uptake (V O 2 ) response, with obese children and adolescents characterised by slower V O 2 kinetics than their normal weight counterparts (Salvadego et al 2010;Lambrick et al 2013;Potter et al 2013). V O 2 kinetics describe the finite rate of adjustment to a sudden change in metabolic demand, thus providing a functional evaluation of the integration of the pulmonary, cardiovascular, and skeletal systems (Whipp and Ward 1990).…”

Section: Introductionmentioning

confidence: 99%

The influence of a six-week, high-intensity games intervention on the pulmonary oxygen uptake kinetics in prepubertal obese and normal-weight children

McNarry

Lambrick

Westrupp

et al. 2015

Appl. Physiol. Nutr. Metab.

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The pulmonary oxygen uptake response is deleteriously influenced by obesity in prepubertal children, as evidenced by a slower phase II response. To date, no studies have investigated the ability of an exercise intervention to ameliorate this. The objective of the study was to investigate the influence of a 6-week, high-intensity, games-orientated intervention on the oxygen uptake kinetic response of prepubertal obese and normal-weight children during heavy-intensity exercise. Thirteen normal-weight and 15 obese children participated in a twice-weekly exercise intervention involving repeated bouts of 6-min high-intensity, games-orientated exercises followed by 2 min of recovery. Sixteen normal-weight and 11 obese children served as a control group. At baseline and post-intervention, each participant completed a graded-exercise test to volitional exhaustion and constant work-rate, heavy-intensity exercise. Post-intervention, obese children demonstrated a reduced phase II τ (pre-intervention: 30 ± 8 cf. post-intervention: 24 ± 7 s), mean response time (pre-intervention: 50 ± 10 cf. post-intervention: 38 ± 9 s) and phase II amplitude (pre-intervention: 1.51 ± 0.30 cf. post-intervention: 1.34 ± 0.27 L·min(-1)). No changes were evident in the normal-weight children. In conclusion, the present findings demonstrate that a 6-week, high-intensity intervention can have a significant positive impact on the dynamic oxygen uptake response of obese prepubertal children.

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Section: Introductionmentioning

confidence: 99%

The influence of a six-week, high-intensity games intervention on the pulmonary oxygen uptake kinetics in prepubertal obese and normal-weight children

McNarry

Lambrick

Westrupp

et al. 2015

Appl. Physiol. Nutr. Metab.

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“…An example of maximal protocol is the Bruce protocol [21], which is performed on a treadmill using incremental speed and incline. Maximal tests are also performed on a cycle ergometer [41,42]. On the contrary, submaximal testing does not require maximal effort; rather participants perform at given intensities, like running against 4, 5.6, and 8 km·h −1 on a treadmill [16,26].…”

Section: Introductionmentioning

confidence: 99%

The Effect of Body Mass Index on Acute Cardiometabolic Responses to Graded Exercise Testing in Children: A Narrative Review

Nikolaidis¹,

Kintziou

Georgoudis

et al. 2018

Sports

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Although the beneficial role of exercise for health is widely recognized, it is not clear to what extent the acute physiological responses (e.g., heart rate (HR) and oxygen uptake (VO2)) to a graded exercise test are influenced by nutritional status (i.e., overweight vs. normal-weight). Therefore, the main objectives of the present narrative review were to examine the effect of nutritional status on acute HR, and VO2 responses of children to exercise testing. For this purpose, we examined existing literature using PubMed, ISI, Scopus, and Google Scholar search engines. Compared with their normal-body mass index (BMI) peers, a trend of higher HRrest, higher HR during submaximal exercise testing, and lower HRmax was observed among overweight and obese children (according to BMI). Independent from exercise mode (walking, running, cycling, or stepping), exercise testing was metabolically more demanding (i.e., higher VO2) for obese and overweight children than for their normal-weight peers. Considering these cardiometabolic differences according to BMI in children might help exercise specialists to evaluate the outcome of a graded exercise test (GXT) (e.g., VO2max, HRmax) and to prescribe optimal exercise intensity in the context of development of exercise programs for the management of body mass.

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“…A number of studies have attempted to determine the value of τ (the time constant for the first-order linear equation) for gas exchange and HR variables in children (7;26). Factors such as maturational status and the presence of disease and obesity appear to play a role (32;39). After the initial minutes of the ramp test,

\overset{•}{V} O_{2}

approaches a linear increase as the ramp progresses.…”

Section: Introductionmentioning

confidence: 99%

Dynamic Interactions of Gas Exchange, Body Mass, and Progressive Exercise in Children

Leu¹,

Galassetti²,

Radom‐Aizik³

2014

Medicine &Amp; Science in Sports &Amp; Exercise

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Purpose Cardiopulmonary exercise testing (CPET) is increasingly used as a biomarker of fitness in children. Maximal or peak values remain the most common variables obtained in CPET, but these physiologically challenging high-intensity work rates are often not achieved. We hypothesized that interactions of gas exchange, heart rate (HR), and work rate (WR) CPET variables (slopes) could yield useful mechanistic and clinical insights that might enhance the clinical utility of CPET in children. We further hypothesized that the dependence of the slope on body mass could be predicted by first-principle analysis of body size and physiological response. Methods One hundred sixty-nine healthy participants (8–18 years old, BMI<95th percentile, 82 females) underwent dual X-ray absorptiometry scan to estimate lean body mass (LBM) and performed a ramp-type progressive cycle ergometry exercise protocol with breath-by-breath measurement of gas exchange. Linear regression was used to calculate the slopes among V•O2,V•normalCO2,normalV•E, HR, and WR. Results ΔWR/ΔHR (r=0.87) and normalΔV•O2/normalΔnormalHnormalRfalse(normalr=0.96false) were strongly correlated with peak V•O2, while normalΔV•O2/normalΔnormalWnormalRfalse(normalr=0.42false) and normalΔnormalV•E/normalΔV•normalCO2false(normalr=−0.51false) were mildly correlated with peak values. LBM was more highly correlated than was total body mass with those slopes predicted to be body size dependent (p<0.0001). Conclusion The data largely supported our original hypotheses. Unlike peak or maximal values, which are derived from no more than a few data points at the end of a progressive exercise test, the CPET slopes were calculated from a much larger data set obtained throughout the test. Analysis of these slopes might ultimately prove useful clinically and in research studies when peak values are not achieved.

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The oxygen uptake kinetic response to moderate intensity exercise in overweight and non-overweight children

Cited by 8 publications

References 34 publications

The influence of a six-week, high-intensity games intervention on the pulmonary oxygen uptake kinetics in prepubertal obese and normal-weight children

The influence of a six-week, high-intensity games intervention on the pulmonary oxygen uptake kinetics in prepubertal obese and normal-weight children

The Effect of Body Mass Index on Acute Cardiometabolic Responses to Graded Exercise Testing in Children: A Narrative Review

Dynamic Interactions of Gas Exchange, Body Mass, and Progressive Exercise in Children

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