2010
DOI: 10.1038/nrneurol.2010.5
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The optic nerve head in acquired optic neuropathies

Abstract: Acquired optic neuropathies are a common cause of blindness in adults, and are associated with characteristic morphological changes at the optic nerve head. Accurate and prompt clinical diagnosis, supplemented with imaging where appropriate, is essential to optimize management of the optic neuropathy and to counsel the patient appropriately on its natural history. History taking, optic disc findings, visual field assessment and imaging of the nerve head and surrounding retinal nerve fiber layer are all paramou… Show more

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Cited by 17 publications
(15 citation statements)
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“…The optic nerve is a potential site for functional disruption due to drug side-effects [58]. An outline of these medications is listed in …”
Section: Medications That May Cause Optic Neuropathymentioning
confidence: 99%
“…The optic nerve is a potential site for functional disruption due to drug side-effects [58]. An outline of these medications is listed in …”
Section: Medications That May Cause Optic Neuropathymentioning
confidence: 99%
“…It may be that the bilateral optic disk edema is associated with sarcoidal CNS involvement. 2,4 Sarcoidosis may also lead to direct granulomatous involvement of the optic disk, 2 Ischemic optic neuropathy, diabetic papillopathy but in that case, there would be further evidence of intraocular inflammation, such as the presence of inflammatory cells in the vitreous. Considering the use of amiodarone and the presence of cornea verticillata, drug-induced neuropathy might also be a possibility, especially if the workup is noncontributory.…”
Section: Questionmentioning
confidence: 99%
“…The ADOA phenotype and degree of vision loss often varies considerably within a given pedigree, with a spectrum of vision loss ranging from mild to severe [6], [7]. The optic neuropathy often manifests in early childhood with reduced visual acuity, a predominantly blue-yellow dyschromatopsia and central scotoma (blind spot) [8], [9].…”
Section: Introductionmentioning
confidence: 99%