“…Some images, such as multivesicular bodies and paramural bodies in the epithelial cells, are evidence of granulocrine secretion (Nair et al 1983;Venkaiah 1992;Carmello et al 1995). Finally, the disruption of the dark epithelial cells followed by the release of their contents into the lumen cavity characterizes a holocrine secretion process (Fahn 1979), which in this species is associated with programmed cell death, as reported by Rodrigues et al (2011b). To our knowledge, the involvement of holocrine as well as eccrine and granulocrine processes in the same secretory system is not common.…”