The nucleotide sequence of the region of bacteriophage T5 early gene D10–D15

Kaliman, A V; Kryukov, V. A.; Bayev, A.A.

doi:10.1093/nar/16.21.10353

Cited by 10 publications

(4 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On the whole, 64.1% codons of the ltfgene end in T and A residues with the greatest preference for codons ending in T residues (38%). Similar distribution was observed for other T5 genes: the D9 gene encoding DNA polymerase [18], the D15 gene encoding 5'-exonuclease [19], the oad gene encoding the receptor-binding protein [20] and the DI0-D14 early genes encoding proteins whose functions have not yet been identified precisely [21].…”

Section: S G a S A P A I R A M W C D G S L A D T T R Y L G A T Q P 11supporting

confidence: 70%

The nucleotide sequence of the bacteriophage T5 ltf gene

et al. 1995

View full text Add to dashboard Cite

Section: S G a S A P A I R A M W C D G S L A D T T R Y L G A T Q P 11supporting

confidence: 70%

The nucleotide sequence of the bacteriophage T5 ltf gene

et al. 1995

View full text Add to dashboard Cite

“…The SbcCD protein and the putative T4 and T5 nucleases (which have previously been shown to share sequence homology; Blinov et aL, 1989) are each composed of two polypeptide chains whose genes are adjacent and are believed to be co-expressed as judged from the DNA sequence (Gram & Ruger, 1985;Kaliman et al, 1988;Naom et al, 1989). The bacteriophage T4 protein has been studied in vivo and in vitro and controls or constitutes the major nuclease activity of the phage responsible for the degradation of the bacterial chromosome upon phage infection (Kutter & Wiberg, 1968).…”

Section: Introductionmentioning

confidence: 99%

The SbcCD protein of Escherichia coli is related to two putative nucleases in the UvrA superfamily of nucleotide-binding proteins

1992

View full text Add to dashboard Cite

The derived amino-acid sequences of the proteins encoded by E. coli genes sbcC and sbcD have been compared with other protein sequences using computer assisted methods. This work has shown that SbcC and D, which inhibit the propagation of replicons containing long palindromic DNA sequences, are distantly related to two putative bacteriophage nucleases. These nucleases both comprise two polypeptide chains which are the products of genes 46 and 47 of bacteriophage T4 (gp 46 and gp 47) and genes D13 and D12 of bacteriophage T5 (gp D13 and gp D12). The comparisons reveal that SbcC, gp 46 and gp D13 are more closely related to each other than are SbcD, gp 47 and gp D12. SbcC appears to have undergone a partial duplication of an ancestral sequence. These proteins all contain motifs common to the superfamily of nucleotide-binding proteins that includes UvrA and the cystic fibrosis transmembrane regulator CFTR.

show abstract

“…Regarding the fp01 genome annotation, we identified that structural genes correlate with the Siphoviridae virion structure of the fp01 phage and its electron microscopy [ 18 ]. Interestingly, among the identified replication-associated genes, D11 and a D14, both essential for the early viral replication cycle, have been described in Escherichia phages T5-like and in lambda-like phages [ 80 , 81 ]. This indicates that fp01 uses its DNA-packing machinery for replication.…”

Section: Discussionmentioning

confidence: 99%

Comparative Genomics of a Polyvalent Escherichia-Salmonella Phage fp01 and In Silico Analysis of Its Receptor Binding Protein and Conserved Enterobacteriaceae Phage Receptor

Vásquez

Retamales

Parra

et al. 2023

Viruses

View full text Add to dashboard Cite

The polyvalent bacteriophage fp01, isolated from wastewater in Valparaiso, Chile, was described to have lytic activity across bacterial species, including Escherichia coli and Salmonella enterica serovars. Due to its polyvalent nature, the bacteriophage fp01 has potential applications in the biomedical, food and agricultural industries. Also, fundamental aspects of polyvalent bacteriophage biology are unknown. In this study, we sequenced and described the complete genome of the polyvalent phage fp01 (MH745368.2) using long- (MinION, Nanopore) and short-reads (MiSeq, Illumina) sequencing. The bacteriophage fp01 genome has 109,515 bp, double-stranded DNA with an average G+C content of 39%, and 158 coding sequences (CDSs). Phage fp01 has genes with high similarity to Escherichia coli, Salmonella enterica, and Shigella sp. phages. Phylogenetic analyses indicated that the phage fp01 is a new Tequintavirus fp01 specie. Receptor binding protein gp108 was identified as potentially responsible for fp01 polyvalent characteristics, which binds to conserved amino acid regions of the FhuA receptor of Enterobacteriaceae.

show abstract

The nucleotide sequence of the region of bacteriophage T5 early gene D10–D15

Cited by 10 publications

References 1 publication

The nucleotide sequence of the bacteriophage T5 ltf gene

The nucleotide sequence of the bacteriophage T5 ltf gene

The SbcCD protein of Escherichia coli is related to two putative nucleases in the UvrA superfamily of nucleotide-binding proteins

Comparative Genomics of a Polyvalent Escherichia-Salmonella Phage fp01 and In Silico Analysis of Its Receptor Binding Protein and Conserved Enterobacteriaceae Phage Receptor

Contact Info

Product

Resources

About