The Noninvasive Diagnosis of Intrathoracic Splenosis Using Technetium-99m Heat-Damaged Red Blood Cells

Intrahepatic and widely distributed intraabdominal splenosis: multidetector CT, US and scintigraphic findings

“…Extraperitoneal locations have also been reported such as retroperitoneal, intrahepatic [4][5][6], renal [7], thoracic, either parenchimal, pleural or pericardic [8][9][10] and subcutaneous [11]. A unique case of cerebral spleen has been described so far [12].…”

“…Indeed, intrahepatic nodules remained non-viewable in our patient. Heat-damaged red blood cell scintigraphy is more sensitive than radiocolloids scintigraphy due to its improved target to background ratio [9,14].…”

Intraperitoneal splenosis: CT and MRI evaluation

“…Additionally, single positron emission tomography has the advantage of direct correlation with other imaging techniques. Tc-99m heat-damaged erythrocytes or In-111 labeled platelets are more sensitive than Tc-99m sulfur colloid in the detection of this tissue because of their better signal-to-background ratio, and their specificity for splenic tissue (13,20,21).…”

SPECT demonstration of splenosis

“…1,15 In addition, unusual cases of retroperitoneal and intrathoracic splenosis have been reported. 5,14 The peripheral blood supply of splenulus is derived from small perforating vessels that arise at the implanted site.…”

“…-13 There are several reports of splenosis mimicking tumors not only in the peritoneal space but also in the intrathoracic and perirenal space. 5,14 The phagocytic Kupffer's cells of the reticuloReceived October 7, 1991, revision accepted December 11, 1991. For reprints contact: Shoji Yoshida, M.D., Department of Radiology, Hyogo Medical Center for Adults, Kitaooji-cho, Akashi-shi, Hyogo 673, JAPAN. endothelial system (RES) allow the evaluation of the splenic tissue by means of colloidal substances.…”