The Nicotine Adenine Dinucleotide Requirement of Mycoplasma synoviae

No, Olson; Jk, Meadows

doi:10.2307/1588805

Cited by 9 publications

(3 citation statements)

References 5 publications

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“…Avian reoviruses have since been assochted with several diseases of chickens including cloaca1 pasting (Deshmukh and Pomeroy 1969). ulcerative enteritis (Krauss and Ueberschiir 1966) and synovitis (Olson and Kahn 1972). In Australia, avian reoviruses have been isolated as contaminants of cell cultures prepared from the kidneys of apparently normal chickens ( Mustaffa-Babjee and Spradbrow 1971; Chubb and Ma 1974) and an association with heart lesions and mortalities in young broiler chickens has recently been suggested (Bains ct a1 1974;Spradbrow and Bains 1974).…”

Section: Isolation Of Reoviruses Associated Wlth Diseases Of Chickensmentioning

confidence: 99%

Letters to the Editor

1975

Aust Veterinary J

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Section: Isolation Of Reoviruses Associated Wlth Diseases Of Chickensmentioning

confidence: 99%

Letters to the Editor

1975

Aust Veterinary J

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“…Mycoplasma synoviae (MS) is an avian pathogen that causes respiratory disease, infectious synovitis, and eggshell apex abnormalities in chickens [1]. Ever since it was first reported in 1954 by Olson et al [2], many studies have been conducted to isolate and incubate MS. After many attempts to design and improve the artificial medium for incubating MS, Chalquest [3], Frey et al [4], and Olson and Meadow [5] established the use of nicotinamide adenine dinucleotide (NAD) for the in vitro growth of MS.…”

Section: Introductionmentioning

confidence: 99%

Genome Analysis of Nicotinamide Adenine Dinucleotide-Independent Mycoplasma synoviae Isolates From Korea

Song

Kim

et al. 2021

Pathogens

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Mycoplasma synoviae (MS) is an avian pathogen that causes respiratory disease, infectious synovitis, and eggshell apex abnormalities in chickens. Nicotinamide adenine dinucleotide (NAD)-independent MS was first reported in 1975. Despite the atypical traits of NAD-independent MS, its independence from NAD has not been studied. In this study, we isolated five NAD-independent strains from Korea and assembled their genomes using sequencing reads obtained from Illumina and Oxford Nanopore Technology platforms. The assembled genomes were compared with the genomes of MS-H vaccine strain and type strain WVU1853. We found that the coding sequences of nicotinate phosphoribosyltransferase and glycerol-3-phosphate acyltransferase, and a unique coding sequence were present only in the genomes of NAD-independent isolates.

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“…Mycoplasma synoviae, a fastidious mycoplasma with an absolute requirement for oxidized nicotinamide adenine dinucleotide (NAD), causes natural outbreaks of infectious synovitis in chickens (6,10,11). Experimental infection of chickens, either intratracheally or through the footpad, with M. synoviae produces an acute to chronic condition characterized by lesion production predominantly in the joints and heart.…”

mentioning

confidence: 99%

Growth and cytopathology of Mycoplasma synoviae in chicken embryo cell cultures

Aldridge¹

1975

Infect Immun

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Mycoplasma synoviae was tested for its ability to grow and induce cytopathogenic changes in chicken embryo cell cultures. M. synoviae grew to high titers by day 5 in the presence of chick cells, but showed no growth in the tissue culture medium alone even though it was enriched with nicotinamide adenine dinucleotide and swine serum. Infected chick cell cultures showed a progressive cytoplasmic degeneration on successive days of examination. Early changes involved cytoplasmic granularity and mild vacuolation. On the last day of examination the cytoplasm of most cells was completely degenerated and some showed nuclear degeneration. M. synoviae was shown to be cytophilic for the chick cell membranes where the mycoplasmas reproduced and formed microcolonies which, on successive days, increased in size. The attachment site on the chick cell membrane was shown to be neuraminidase sensitive.

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The Nicotine Adenine Dinucleotide Requirement of Mycoplasma synoviae

Cited by 9 publications

References 5 publications

Letters to the Editor

Letters to the Editor

Genome Analysis of Nicotinamide Adenine Dinucleotide-Independent Mycoplasma synoviae Isolates From Korea

Growth and cytopathology of Mycoplasma synoviae in chicken embryo cell cultures

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