The new cutaneous mucinoses: A review with an up-to-date classification of cutaneous mucinoses

Rongioletti, Franco; Rebora, Alfredo

doi:10.1016/0190-9622(91)70040-9

Cited by 114 publications

(111 citation statements)

References 19 publications

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“…1,[5][6][7] This controversy is not easy to resolve, as there is also some debate as to whether LET itself is a separate subtype of chronic CLE, or a nonspecific manifestation within the lupus erythematosus classification system. 8,9 Our present study includes the largest series of cases of REM ever reported in the literature.…”

Section: Discussionmentioning

confidence: 99%

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Reticular erythematous mucinosis: a review of patients' characteristics, associated conditions, therapy and outcome in 25 cases

et al. 2013

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SummaryBackground Reticular erythematous mucinosis (REM) is an uncommon disease, the nosology and specific characteristics of which are controversial because most reports deal with single cases or small series. Objectives To describe the characteristics of patients with REM regarding demographics, clinical and pathological features, comorbidities, treatment and course. Methods A retrospective and prospective study was conducted on 25 patients diagnosed with REM in the setting of university-affiliated dermatology departments and dermatopathology centres. Results Of the 25 patients with REM, 16 were women (sex ratio 2 : 1) and the mean age was 46 years. The roles of sun exposure and oral contraceptives were ambiguous. Associated diseases included hypertension (n = 4), malignancies (n = 3), autoimmune diseases (n = 3) and Borrelia infection (n = 1). Immunological studies (including serology and direct immunofluorescence) were noncontributory. The response to antimalarial treatment was good in > 80% of cases. Worsening or recurrence of the lesion after treatment discontinuation, or in the course of the disease, occurred in 31% of patients. Conclusions We present the largest REM case series to date. The reticular pattern with involvement of the midline of the chest and back, the predilection for middle-aged women, the controversial relationship with photosensitivity and the possible association with other conditions such as malignancies and thyroid dysfunctions are the main characteristics that makes REM a recognizable disease.

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Section: Discussionmentioning

confidence: 99%

“…The inclusion criterion was a clinical and histopathological diagnosis of REM. 5 The clinical criteria were erythematous macules and indurated papules with a reticular configuration, or plaque-like lesions that remained isolated and coalesced into reticulated patterns in the midline of the back or chest (Fig. 1a,b).…”

Section: Methodsmentioning

confidence: 99%

Reticular erythematous mucinosis: a review of patients' characteristics, associated conditions, therapy and outcome in 25 cases

et al. 2013

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“…Cutaneous mucinoses are a wide group of disorders characterized by anomalous deposits of mucin in the skin 1 . Lichen myxoedematosus can be classifi ed into several subtypes, depending on the distribution and overall skin involvement.…”

Section: Discussionmentioning

confidence: 99%

Discrete papular lichen myxoedematosus: A case report

Cengiz¹

2014

Kafkas J Med Sci

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Case ReportA 49-year-old woman was referred to our department with asymptomatic papules of 3 months' duration on the upper back. Physical examination revealed numerous well-defi ned, white papules, 3-5 mm in diameter (Figure 1). Th ere wasn't any induration or thickening of the skin on the aff ected site. In addition, there was no history of preceding trauma and the patient was not taking any medication.Routine laboratory studies were unremarkable. Serum electrophoresis and thyroid function tests were normal. Screening for viral infections remained negative. General physical examination did not reveal any systemic involvement.A 4-mm punch biopsy was performed from one of the lesions located on the upper part of the back. Histopathological examination showed normal epidermis and widely separated collagen fi bers (Figure 2). PAS + Alcian Blue staining showed an increase in blue staining, which indicated an increase in dermal mucin (Figure 3). Based on the clinical, histological and laboratory fi ndings we have diagnosed the discrete papular type of lichen myxoedematosus.Although topical corticosteroids had been previously administered for three months, they had been ineffective. Because the patient was asymptomatic, we preferred to follow conservatively. During the followup of 20 months, we did not observe any evidence of spontaneous resolution or progression.

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“…Four cases of self-healing cutaneous mucinosis are known so far. They were all in children [ 1 ] with multiple lesions and polyarthritis.…”

Section: Discussionmentioning

confidence: 99%

Self-Healing Localized Cutaneous Mucinosis

Cannata¹,

Gambini

Ciaccio³

1994

Dermatology

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The new cutaneous mucinoses: A review with an up-to-date classification of cutaneous mucinoses

Cited by 114 publications

References 19 publications

Reticular erythematous mucinosis: a review of patients' characteristics, associated conditions, therapy and outcome in 25 cases

Reticular erythematous mucinosis: a review of patients' characteristics, associated conditions, therapy and outcome in 25 cases

Discrete papular lichen myxoedematosus: A case report

Self-Healing Localized Cutaneous Mucinosis

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