The Nephrotic Syndrome in Early Infancy: A Report of Three Cases

Immunosuppressive therapy in steroid-resistant proliferative glomerulonephritis accompanied by the nephrotic syndrome.

“…Interstitial oedema and round-cell infiltration, and tubular atrophy were absent in Cases 4 and 7 and patchy in Cases 2 and 3, but were more marked in Case 9. However, Case 1, a congenital nephrotic, showed striking dilatation and reduction in number of the proximal tubules, together with interstitial fibrosis, suggesting " microcystic disease " (Giles et al, 1957).…”

Congenital Anomalies of Renal Tubules in a Case of "Infantile Nephrosis"

“…1 The association of renal vein thrombosis with the nephrotic syndrome in a wide age group is well known,2,3 and one case occurring in infancy has been reported. 4 In the case to be presented, a prematurely born infant who displayed the nephrotic syndrome was found to have both longstanding thrombosis of the right renal vein and the inferior vena cava and, as shown by microdissection of the kidneys, congenital defects of the proximal convoluted tubules.…”

An Infantile Case of Nephrotic Syndrome: Successfully Treated with Intravenous Administration of ACTH, and Complicated with “Recovery Syndrome (Gömez)”

“…[1][2][3][4][5][6][7][8] In the present paper, an infantile case of nephrotic syndrome will be described with special references to the following points : 1) A remission could be initiated by an intravenous administration of ACTH, but not by preceding dosage of steroid hormones, 2) "nutritional recovery syndrome of Gomez" was observed in recovery stage of our own nephrotic case, and 3) both electron-and light microscopic findings of biopsied kidney showed a close relation to clinical course of the disease. CASE costal margin.…”