The multiple effects of hydrogen sulfide on cadmium toxicity in tobacco may be interacted with CaM signal transduction

Wang, Hongrui; Che, Yanhui; Wang, Zihan; Zhang, Beining; Huang, Dan; Feng, Fude; Ao, Hong Rui

doi:10.1016/j.jhazmat.2020.123651

Cited by 41 publications

(16 citation statements)

References 24 publications

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“…The endogenous production of proline and MeJA enhanced by H 2 S donor NaHS responded significantly to Cd stress in foxtail millet [122,123]. H 2 S also improved CaM gene expression and controlled the combination of Ca 2+ and CaM, which act as signal transducers [33].…”

Section: H 2 S Action In Plant Tolerance Against CD Stressmentioning

confidence: 94%

“…MeJA enhanced by H2S donor NaHS responded significantly to Cd stress in foxtail millet [122,123]. H2S also improved CaM gene expression and controlled the combination of Ca 2+ and CaM, which act as signal transducers [33]. There exists a complicated and synergistic relationship between H2S and NO in response to Cd stress in plants (Figure 4; [115,118,124,125]).…”

Section: H 2 S Action In Plant Tolerance Against CD Stressmentioning

confidence: 99%

“…Exogenous application of H 2 S donors regulated plant growth, and conferred tolerance to salinity, heavy metal, heat, and drought stress among others [27,31,32]. H 2 S enhanced photosynthesis and antioxidant enzyme activity, and up-regulated the transcripts of PC genes to alleviate Cd stress in tobacco [33]. Moreover, H 2 S homeostasis and L-cysteine desulfhydrase activity were involved in melatonin-modulated salt stress tolerance in tomato and cucumber seedlings [31,34,35].…”

Section: Introductionmentioning

confidence: 99%

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Melatonin Confers Plant Cadmium Tolerance: An Update

Wang

Xiao

et al. 2021

IJMS

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Cadmium (Cd) is one of the most injurious heavy metals, affecting plant growth and development. Melatonin (N-acetyl-5-methoxytryptamine) was discovered in plants in 1995, and it is since known to act as a multifunctional molecule to alleviate abiotic and biotic stresses, especially Cd stress. Endogenously triggered or exogenously applied melatonin re-establishes the redox homeostasis by the improvement of the antioxidant defense system. It can also affect the Cd transportation and sequestration by regulating the transcripts of genes related to the major metal transport system, as well as the increase in glutathione (GSH) and phytochelatins (PCs). Melatonin activates several downstream signals, such as nitric oxide (NO), hydrogen peroxide (H2O2), and salicylic acid (SA), which are required for plant Cd tolerance. Similar to the physiological functions of NO, hydrogen sulfide (H2S) is also involved in the abiotic stress-related processes in plants. Moreover, exogenous melatonin induces H2S generation in plants under salinity or heat stress. However, the involvement of H2S action in melatonin-induced Cd tolerance is still largely unknown. In this review, we summarize the progresses in various physiological and molecular mechanisms regulated by melatonin in plants under Cd stress. The complex interactions between melatonin and H2S in acquisition of Cd stress tolerance are also discussed.

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Section: H 2 S Action In Plant Tolerance Against CD Stressmentioning

confidence: 94%

Section: H 2 S Action In Plant Tolerance Against CD Stressmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Melatonin Confers Plant Cadmium Tolerance: An Update

Wang

Xiao

et al. 2021

IJMS

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“…However, Zn supplementation significantly reduced the concentration of lipid peroxides and inhibited the increase in oxidative stress levels induced by Cd (17). Wang et al have shown that hydrogen sulfide (H 2 S) antagonizes Cd 2+ by regulating the antioxidant system, alleviating cell membrane damage, and maintaining intracellular homeostasis (113). In addition, H 2 S can also reduce inflammatory cell responses by inhibiting NF-kB pathway activation (114).…”

Section: Potential Ways To Alleviate CD Cytotoxicitymentioning

confidence: 99%

“…Wang et al. have shown that hydrogen sulfide (H 2 S) antagonizes Cd 2+ by regulating the antioxidant system, alleviating cell membrane damage, and maintaining intracellular homeostasis ( 113 ). In addition, H 2 S can also reduce inflammatory cell responses by inhibiting NF-κB pathway activation ( 114 ).…”

Section: Potential Ways To Alleviate CD Cytotoxicitymentioning

confidence: 99%

Effects of Cadmium Exposure on the Immune System and Immunoregulation

et al. 2021

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Cadmium (Cd), a biologically non-essential heavy metal, is widespread in the environment, including the air, water, and soil, and is widely present in foods and quantum dot preparations. Cd enters the body primarily through inhalation and ingestion. Its biological half-life in humans is 10–35 years; therefore, Cd poses long-term health risks. While most studies on Cd toxicity have focused on organ and tissue damage, the immunotoxicity of Cd has drawn increasing attention recently. Cd accumulates in immune cells, modulates the function of the immune system, triggers immunological responses, and leads to diverse health problems. Cd acts as an immunotoxic agent by regulating the activity and apoptosis of immune cells, altering the secretion of immune cytokines, inducing reactive oxygen species (ROS) production and oxidative stress, changing the frequency of T lymphocyte subsets, and altering the production of selective antibodies in immune cells. This review summarizes the immunological toxicity of Cd, elucidates the mechanisms underlying Cd toxicity in terms of innate immunity and adaptive immunity, and discusses potential strategies to alleviate the adverse effects of Cd on the immune system.

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Rhizosphere interface microbiome reassembly by arbuscular mycorrhizal fungi weakens cadmium migration dynamics

Wang,

Du,

Zhang

et al. 2023

iMeta

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The prevalence of cadmium (Cd)‐polluted agricultural soils is increasing globally, and arbuscular mycorrhizal fungi (AMF) can reduce the absorption of heavy metals by plants and improve mineral nutrition. However, the immobilization of the rhizosphere on cadmium is often overlooked. In this study, Glomus mosseae and Medicago sativa were established as symbiotes, and Cd migration and environmental properties in the rhizosphere were analyzed. AMF reduced Cd migration, and Cd2+ changed to an organic‐bound state. AMF symbiosis treatment and Cd exposure resulted in microbial community variation, exhibiting a distinct deterministic process (|βNTI| > 2), which ultimately resulted in a core microbiome function of heavy metal resistance and nutrient cycling. AMF increased available N and P, extracellular enzyme activity (LaC, LiP, and CAT), organic matter content (TOC, EOC, and GRSP), and Eh of the rhizosphere soil, significantly correlating with decreased Cd migration (p < 0.05). Furthermore, AMF significantly affected root metabolism by upregulating 739 metabolites, with flavonoids being the main factor causing microbiome variation. The structural equation model and variance partial analysis revealed that the superposition of the root metabolites, microbial, and soil exhibited the maximum explanation rate for Cd migration reduction (42.4%), and the microbial model had the highest single explanation rate (15.5%). Thus, the AMF in the rhizosphere microenvironment can regulate metabolite–soil–microbial interactions, reducing Cd migration. In summary, the study provides a new scientific explanation for how AMF improves plant Cd tolerance and offers a sustainable solution that could benefit both the environment and human health.

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The multiple effects of hydrogen sulfide on cadmium toxicity in tobacco may be interacted with CaM signal transduction

Cited by 41 publications

References 24 publications

Melatonin Confers Plant Cadmium Tolerance: An Update

Melatonin Confers Plant Cadmium Tolerance: An Update

Effects of Cadmium Exposure on the Immune System and Immunoregulation

Rhizosphere interface microbiome reassembly by arbuscular mycorrhizal fungi weakens cadmium migration dynamics

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