The mortality impacts of fine particles in France

Pascal, Mathilde; Chanel, Perrine de Crouy; Wagner, Vérène; Corso, Magali; Tillier, Claude; Bentayeb, Malek; Blanchard, Myriam; Cochet, Amandine; Pascal, Laurence; Host, Sabine; Goria, Sarah; Tertre, Alain Le; Chatignoux, Édouard; Ung, Aymeric; Beaudeau, Pascal; Médina, Sylvia

doi:10.1016/j.scitotenv.2016.06.213

Cited by 35 publications

(23 citation statements)

References 21 publications

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“…To answer this emerging demand, several methods for estimating personal exposure have been developed. Land-use regression models have been largely used to relate concentrations measured at monitor sites with concentration estimates at different locations across the city (Beelen et al, 2013;Cattani et al, 2017;Ryan and LeMasters, 2007). Then, space-time activity data are coupled to concentration data to provide exposure estimates (Vizcaino and Lavalle, 2018;Xu et al, 2019a).…”

Section: Introductionmentioning

confidence: 99%

EXPLUME v1.0: a model for personal exposure to ambient O3 and PM2.5

et al. 2020

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Abstract. This paper presents the first version of the regional-scale personal exposure model EXPLUME (EXposure to atmospheric PolLUtion ModEling). The model uses simulated gridded data of outdoor O3 and PM2.5 concentrations and several population and building-related datasets to simulate (1) space–time activity event sequences, (2) the infiltration of atmospheric contaminants indoors, and (3) daily aggregated personal exposure. The model is applied over the greater Paris region at 2 km×2 km resolution for the entire year of 2017. Annual averaged population exposure is discussed. We show that population mobility within the region, disregarding pollutant concentrations indoors, has only a small effect on average daily exposure. By contrast, considering the infiltration of PM2.5 in buildings decreases annual average exposure by 11 % (population average). Moreover, accounting for PM2.5 exposure during transportation (in vehicle, while waiting on subway platforms, and while crossing on-road tunnels) increases average population exposure by 5 %. We show that the spatial distribution of PM2.5 and O3 exposure is similar to the concentration maps over the region, but the exposure scale is very different when accounting for indoor exposure. We model large intra-population variability in PM2.5 exposure as a function of the transportation mode, especially for the upper percentiles of the distribution. Overall, 20 % of the population using bicycles or motorcycles is exposed to annual average PM2.5 concentrations above the EU target value (25 µg m−3), compared to 0 % for people travelling by car. Finally, we develop a 2050 horizon projection of the building stock to study how changes in the buildings' characteristics to comply with the thermal regulations will affect personal exposure. We show that exposure to ozone will decrease by as much as 14 % as a result of this projection, whereas there is no significant impact on exposure to PM2.5.

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Section: Introductionmentioning

confidence: 99%

EXPLUME v1.0: a model for personal exposure to ambient O3 and PM2.5

et al. 2020

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“…According to the World Health Organization, outdoor air pollution caused 3.7 million deaths globally in 2012 and 9% of the total mortality in France was recently attributed to particulate matter with a diameter ⩽2.5 µm (PM2.5) [1]. The most studied pollutants in relation to health effects are nitrogen dioxide (NO 2 ), ozone (O 3 ), and particulate matter with a diameter ⩽10 µm (PM10) and PM2.5.…”

Section: Introductionmentioning

confidence: 99%

Outdoor air pollution, exhaled 8-isoprostane and current asthma in adults: the EGEA study

et al. 2018

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Associations between outdoor air pollution and asthma in adults are still scarce, and the underlying biological mechanisms are poorly understood. Our aim was to study the associations between 1) long-term exposure to outdoor air pollution and current asthma, 2) exhaled 8-isoprostane (8-iso; a biomarker related to oxidative stress) and current asthma, and 3) outdoor air pollution and exhaled 8-iso.Cross-sectional analyses were conducted in 608 adults (39% with current asthma) from the first follow-up of the French case-control and family study on asthma (EGEA; the Epidemiological study of the Genetic and Environmental factors of Asthma). Data on nitrogen dioxide, nitrogen oxides, particulate matter with a diameter ≤10 and ≤2.5 µm (PM and PM), road traffic, and ozone (O) were from ESCAPE (European Study of Cohorts for Air Pollution Effects) and IFEN (French Institute for the Environment) assessments. Models took account of city and familial dependence.The risk of current asthma increased with traffic intensity (adjusted (a)OR 1.09 (95% CI 1.00-1.18) per 5000 vehicles per day), with O exposure (aOR 2.04 (95% CI 1.27-3.29) per 10 µg·m) and with exhaled 8-iso concentration (aOR 1.50 (95% CI 1.06-2.12) per 1 pg·mL). Among participants without asthma, exhaled 8-iso concentration increased with PM exposure (adjusted (a)β 0.23 (95% CI 0.005-0.46) per 5 µg·m), and decreased with O and O exposures (aβ -0.20 (95% CI -0.39- -0.01) and aβ -0.52 (95% CI -0.77- -0.26) per 10 µg·m, respectively).Our results add new insights into a potential role of oxidative stress in the associations between outdoor air pollution and asthma in adults.

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“…Illustrée par l'indicateur sanitaire de la mortalité prématurée, l'étude établit que l'exposition chronique de la population aux particules fines est responsable de 50 000 morts prématurées par an en 2005. Ce résultat est cohérent avec les 48 000 morts prématurées estimées dans la récente étude de Santé Publique France (Pascal et al, 2016). La mise en place de davantage de mesures de réduction des émissions en France et en Europe réduit ce nombre.…”

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Aide aux décideurs - Évaluation des coûts et des bénéfices sanitaires de politiques de lutte contre la pollution de l’air

Schucht

Colette

Brignon

et al. 2017

Pollution Atmosphérique

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Keywords RésuméUne chaîne de modèles intégrés a été mise en oeuvre à l'INERIS, qui permet d'évaluer des politiques de lutte contre la pollution atmosphérique en termes de coûts des actions, de leurs effets sur la qualité de l'air et des bénéfices sanitaires associés. Elle permet de quantifier puis monétiser ces effets sanitaires, aussi bien des mesures individuelles de réduction des émissions atmosphériques que des scénarios (jeux de mesures complexes) de mise en oeuvre de politiques publiques, et de tenir compte de l'impact du changement climatique sur la qualité de l'air. L'article présente brièvement cette chaîne de modèles et illustre ses domaines d'applications sur la base d'exemples d'études récentes d'appui aux pouvoirs publics et de projets de recherche. Les résultats de ces études montrent que beaucoup d'actions pour améliorer la qualité de l'air actuellement envisagées permettent d'obtenir des bénéfices pour la santé, dont la valeur monétaire dépasse largement les coûts des politiques. Ils illustrent aussi les avantages d'une coopération internationale dans la lutte contre la pollution de l'air. Mots-cléspollution de l'air, qualité de l'air, analyse d'impacts sanitaires, coûts sanitaires, analyse coûts/bénéfices, changement climatique, modélisation atmosphérique, analyse de scénarios Abstract An integrated modelling chain capable of evaluating air pollution policies with respect to their costs, their impacts on air quality and associated health effects was implemented at INERIS. It allows quantifying and monetising health effects of both individual emission reduction measures and policy scenarios (complex sets of measures), and also taking into account the air quality impact of climate change. The paper briefly presents this modelling chain and illustrates different application domains based on examples of recent decision support and research projects.The results of these studies show that many policy measures aimed at improving air quality that are currently envisaged will entail health benefits the monetary value of which exceeds the policies' costs by large. They also illustrate the advantages of international cooperation in combatting air pollution.

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The mortality impacts of fine particles in France

Cited by 35 publications

References 21 publications

EXPLUME v1.0: a model for personal exposure to ambient O<sub>3</sub> and PM<sub>2.5</sub>

EXPLUME v1.0: a model for personal exposure to ambient O<sub>3</sub> and PM<sub>2.5</sub>

Outdoor air pollution, exhaled 8-isoprostane and current asthma in adults: the EGEA study

Aide aux décideurs - Évaluation des coûts et des bénéfices sanitaires de politiques de lutte contre la pollution de l’air

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The mortality impacts of fine particles in France

Cited by 35 publications

References 21 publications

EXPLUME v1.0: a model for personal exposure to ambient O&lt;sub&gt;3&lt;/sub&gt; and PM&lt;sub&gt;2.5&lt;/sub&gt;

EXPLUME v1.0: a model for personal exposure to ambient O&lt;sub&gt;3&lt;/sub&gt; and PM&lt;sub&gt;2.5&lt;/sub&gt;

Outdoor air pollution, exhaled 8-isoprostane and current asthma in adults: the EGEA study

Aide aux décideurs - Évaluation des coûts et des bénéfices sanitaires de politiques de lutte contre la pollution de l’air

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EXPLUME v1.0: a model for personal exposure to ambient O<sub>3</sub> and PM<sub>2.5</sub>

EXPLUME v1.0: a model for personal exposure to ambient O<sub>3</sub> and PM<sub>2.5</sub>