The morphology of articular cartilage assessed by magnetic resonance imaging (MRI)

Eckstein, F.; Sittek, H.; Milz, Stefan; Putz, Reinhard; Reiser, Maximilian

doi:10.1007/bf01627667

Cited by 93 publications

(50 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Loss of cartilage thickness was predicted with 72% sensitivity and 69% specificity; however, sensitivity for cartilage surface integrity was lower and specificity was higher (69% and 74%, respectively). While others have assessed the diagnostic performance of MRI for cartilage lesions using histology [25][26][27][28][29][30], few [9,10,22] have determined the diagnostic performance of FSE sequences with comparison to histology. Our outcomes are comparable to some, but slightly lower than the findings of other investigators in sensitivity and specificity.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic performance of in vivo 3-T MRI for articular cartilage abnormalities in human osteoarthritic knees using histology as standard of reference

et al. 2008

View full text Add to dashboard Cite

The purpose of this study was (1) to evaluate the sensitivity, specificity and accuracy of sagittal in vivo 3-T intermediate-weighted fast spin-echo (iwFSE) sequences in the assessment of knee cartilage pathologies using histology as the reference standard in patients undergoing total knee replacement, and (2) to correlate MR imaging findings typically associated with osteoarthritis such as bone marrow edema pattern (BMEP) and cartilage swelling with histological findings. Tibial plateaus and femoral condyles of eight knees of seven patients were resected during surgery, and sagittal histological sections were prepared for histology. Preoperative MRI findings were compared to the corresponding region in histological sections for thickness, surface integrity and signal pattern of cartilage, and histological findings in areas of BMEP and swelling were documented. The overall sensitivity, specificity and accuracy were 72%, 69% and 70% for thickness, 69%, 74% and 73% for surface and 36%, 62% and 45% for intracartilaginous signal pattern. For all cases of BMEP on MRI subchondral © European Society of Radiology 2008Correspondence to: Thomas M. Link. NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author Manuscript ingrowth of fibrovascular tissue and increased bone remodeling were observed. MRI using fatsaturated iwFSE sequences showed good performance in assessing cartilage thickness and surface lesions, while signal changes of cartilage were not suited to characterize the severity of cartilage degeneration as validated by histology. NIH Public AccessAuthor Manuscript Eur Radiol. Author manuscript; available in PMC 2010 March 15.

show abstract

Section: Discussionmentioning

confidence: 99%

Diagnostic performance of in vivo 3-T MRI for articular cartilage abnormalities in human osteoarthritic knees using histology as standard of reference

et al. 2008

View full text Add to dashboard Cite

show abstract

“…It is an excellent research instrument for articular tissue and there is considerable potential for expansion of the role of MRI in clinical practice. [13][14][15][16] Extensive work by Eckstein et al [17][18][19][20] has shown spoiled 3D gradient echo (FLASH) sequences with water excitation to be particularly useful. However, most articular cartilage imaging work has concentrated on the knee joint, [21][22][23][24][25][26] which displays the thickest articular cartilage layers in the human body.…”

Section: Introductionmentioning

confidence: 99%

“…Previous studies have performed segmentation using a variety of techniques including: manual segmentation, 18,21,[29][30][31][32] seed point and region growing algorithms, [33][34][35] and edge detection followed by spline-based smoothing, 21 all of which have limitations in noisy images of thin cartilage layers of highly congruent joints. Fully manual surface extraction and segmentation 18,21,[29][30][31][32] is tedious, time consuming, and prone to subjective judgment. Fully automated processes 36,37 at present cannot accurately and reproducibly extract and segment articular cartilage layers in areas where the boundary is not sufficiently distinct or in noisy images.…”

Section: Introductionmentioning

confidence: 99%

Quantitative and topographical evaluation of ankle articular cartilage using high resolution MRI

Millington

Tang

et al. 2006

Journal Orthopaedic Research

View full text Add to dashboard Cite

The objectives of this study were to quantitatively evaluate the articular cartilage layers of the ankle and describe the cartilage topographical distribution across the joint surfaces using high resolution MRI and image segmentation. An anisotropic diffusion noise reduction algorithm and a directional gradient vector flow (dGVF) snake segmentation algorithm were applied to cartilage sensitive MR images. Eight cadaveric ankles were studied. Six repeated data sets were acquired in five of the ankles. Quantitative parameters were calculated for each cartilage layer; coefficients of variation (CV) were calculated from the six repeated data sets; and 3D thickness distribution maps were generated. The noise reduction algorithm produced marked image enhancement. Mean cartilage thickness ranged from 0.91 AE 0.08 mm in the fibula to 1.34 AE 0.14 mm in the talus. Mean cartilage volume was 3.32 AE 0.55 ml, 1.72 AE 0.25 ml, and 0.35 AE 0.06 ml for the talus, tibia, and fibula, respectively. Mean CV ranged 2.82%-5.04% for quantitative parameters in the talus and tibia. The reported noise reduction and segmentation technique allow precise extraction of ankle cartilage and 3D reconstructions show that the thickest cartilage occurs over the talar shoulders, where osteochondritits dissecans (OCD) lesions commonly occur. ß

show abstract

“…Studies have shown that MRI is an accurate method of soft tissue and bone dimension measurement and volume assessment, and it has been used to estimate accurate morphological information of different tissues, e.g., bone, muscle, and articular cartilage [19][20][21][22][23][24][25][26].…”

Section: Introductionmentioning

confidence: 99%

Examination of anticipated chemical shift and shape distortion effect on materials commonly used in prosthetic socket fabrication when measured using MRI: A validation study

Safari¹,

Rowe²,

Buis³

2013

JRRD

View full text Add to dashboard Cite

Abstract-The quality of lower-limb prosthetic socket fit is influenced by shape and volume consistency during the residual limb shape-capturing process (i.e., casting). Casting can be quantified with magnetic resonance imaging (MRI) technology. However, chemical shift artifact and image distortion may influence the accuracy of MRI when common socket/casting materials are used. We used a purpose-designed rig to examine seven different materials commonly used in socket fabrication during exposure to MRI. The rig incorporated glass marker tubes filled with water doped with 1 g/L copper sulfate (CS) and 9 plastic sample vials (film containers) to hold the specific material specimens. The specimens were scanned 9 times in different configurations. The absolute mean difference of the glass marker tube length was 1.39 mm (2.98%) (minimum = 0.13 mm [0.30%], maximum = 5.47 mm [14.03%], standard deviation = 0.89 mm). The absolute shift for all materials was <1.7 mm. This was less than the measurement tolerance of +/-2.18 mm based on voxel (three-dimensional pixel) dimensions. The results show that MRI is an accurate and repeatable method for dimensional measurement when using matter containing water. Additionally, silicone and plaster of paris plus 1 g/L CS do not show a significant shape distortion nor do they interfere with the MRI image of the residual limb.

show abstract

The morphology of articular cartilage assessed by magnetic resonance imaging (MRI)

Cited by 93 publications

References 39 publications

Diagnostic performance of in vivo 3-T MRI for articular cartilage abnormalities in human osteoarthritic knees using histology as standard of reference

Diagnostic performance of in vivo 3-T MRI for articular cartilage abnormalities in human osteoarthritic knees using histology as standard of reference

Quantitative and topographical evaluation of ankle articular cartilage using high resolution MRI

Examination of anticipated chemical shift and shape distortion effect on materials commonly used in prosthetic socket fabrication when measured using MRI: A validation study

Contact Info

Product

Resources

About