The mobilization of CD34 positive mononuclear cells after myocardial infarction is abolished by revascularization of the culprit vessel

Role of Endothelial Progenitor Cell Mobilization After Percutaneous Angioplasty Procedure

“…A diametrically opposite result was obtained in a similar study [115] that tried to evaluate the effect of PCI assessing CD34 + levels at day 5 after the onset of symptoms in AMI patients with rapid PCI or without early PCI. A higher CD34 + count was observed in patients without PCI.…”

Parameters influencing LVEF improvement with intracoronary bone marrow stem cell delivery in acute myocardial infarction

“…Because these baseline parameters do not seem to be directly related to each other, the reason why the BMSCs are impaired in patients who have lower baseline LVEF is still unclear. The patients without reperfusion were reported to have higher mobilized stem cells in circulation [5]. Therefore, this was maybe because of the mobilization of the SCs from the bone marrow which was higher in patients who received reperfusion relatively late or no reperfusion and thus relatively had more diminished myocardium.…”

Factores que influyen en la liberación de células endoteliales progenitoras y citocinas angiogénicas tras un infarto de miocardio extenso

“…Los pacientes hipertensos presentaron mayor recuento de cé lulas CD34 + 133 + : mediana (extremos) de 200 (100-328) frente a 97 (0-147), p = 0,02. Existió una tendencia a encontrar mayores valores de citoquinas en los hipertensos: VEGF 12,3 pg/ml (7-74,03) frente a 7 pg/ml (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)25), p = 0,13; SDF-1 1.653 pg/ml (1.427-1.926) frente a 1.426 pg/ml (1.330-1.726), p = 0,075. Por otra parte, dichos pacientes presentaron una fuerte correlació n en ambos ejes: VEGF/CD34 + CD133 + KDR + : r = 0,7, p < 0,01; y SDF-1/CD34 + CXCR4 + r = 0,59, p = 0,003.…”