OBJECTIVES The objective of this clinical trial was to assess the safety and efficacy of carotid BAT in advanced HF.BACKGROUND Increased sympathetic and decreased parasympathetic activity contribute to heart failure (HF) symp-
The enhanced sensitivity of failing human myocardium toward cardiac glycosides may be, at least in part, attributed to a reduced protein expression and activity of the sarcolemmal Na+,K+-ATPase without a change in Na+-Ca2+ exchanger protein expression.
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