The mitochondrial genome of Moniliophthora roreri, the frosty pod rot pathogen of cacao

Costa, Gustavo G.L.; Cabrera, Odalys García; Tiburcio, Ricardo Augusto; Medrano, Francisco J.; Carazzolle, Marcelo Falsarella; Thomazella, Daniela P. T.; Schuster, Stephen C.; Carlson, John E.; Guiltinan, Mark J.; Bailey, Bryan A.; Mieczkowski, Piotr A.; Pereira, Gonçalo Amarante Guimarães; Meinhardt, Lyndel W.

doi:10.1016/j.funbio.2012.01.008

Cited by 35 publications

(33 citation statements)

References 54 publications

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“…The large fungal mitochondrial genomes, alike P. radiata mtDNA, expand over 100 kb in size and may include over 50 protein-coding ORFs (Table 5). The tendency for larger fungal mt genomes (over 90 kbp) in the Basidiomycota subphylum Agaricomycotina is pinpointed by recent reports on Moniliopthora perniciosa and M. roreri [24], [28], T. cingulata (over 90 kb) [26], A. bisporus (135 kbp) [23] and R. solani (165 kbp/235 kbp) [50]. This tendency is furthermore confirmed by our study on the 156 kbp P. radiata mtDNA showing up to 126 predicted protein-coding ORFs and 30 RNA genes, which are the second highest numbers reported for the fungal mitochondrial genomes.…”

Section: Discussionmentioning

confidence: 97%

“…Only slight differences, however, in mtDNA size, gene number and organisation have been observed in the Basidiomycota genera Moniliophthora (Agaricomycotina) [24], [28], Tilletia (Ustilaginomycotina) [19], Phakopsora (Pucciniomycotina) [27], and Cryptococcus (Agaricomycotina) [53], [54], thus indicating genus-level conservation of the mitochondrial genomes in the phylum Basidiomycota. The large differences in gene order and location (loss of synteny) between the Basidiomycota mitochondrial genomes at higher taxon levels, as was reported for Ganoderma lucidum (Agaricomycotina) mtDNA [55], and is observed in this study for P. radiata mtDNA, may thus indicate frequent recombination events and flexibility of fungal organelle genomes.…”

Section: Discussionmentioning

confidence: 99%

“…The overwhelming majority (124) of these belong to Ascomycota [19]. Basidiomycota are the second best represented fungal phylum with 21 complete mt genomes [19], [23]–[28]. The other publicly available fungal mtDNAs include a few genomes from species of Blastocladiomycota, Chytridiomycota, Glomeromycota, Monoblepharidomycota, one Cryptomycota ( Rozella allomycis ), and three previous Zygomycota, now incertae sedis species [19].…”

Section: Introductionmentioning

confidence: 99%

“…Another common, but more randomly distributed fungal mtDNA-contained gene is rps3 , which encodes the small ribosomal subunit protein S3. Other typical genes to fungal mtDNA are the small ( rns ) and large ( rnl ) subunit mitochondrial rRNAs, and a tRNA set - generally at least 23 unique anticodons - sufficient to translate the mtDNA-encoded proteome [7], [8], [10], [23]–[28]. However, exceptions are not unusual.…”

Section: Introductionmentioning

confidence: 99%

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Mitochondrial Genome of Phlebia radiata Is the Second Largest (156 kbp) among Fungi and Features Signs of Genome Flexibility and Recent Recombination Events

et al. 2014

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Mitochondria are eukaryotic organelles supporting individual life-style via generation of proton motive force and cellular energy, and indispensable metabolic pathways. As part of genome sequencing of the white rot Basidiomycota species Phlebia radiata, we first assembled its mitochondrial genome (mtDNA). So far, the 156 348 bp mtDNA is the second largest described for fungi, and of considerable size among eukaryotes. The P. radiata mtDNA assembled as single circular dsDNA molecule containing genes for the large and small ribosomal RNAs, 28 transfer RNAs, and over 100 open reading frames encoding the 14 fungal conserved protein subunits of the mitochondrial complexes I, III, IV, and V. Two genes (atp6 and tRNA-IleGAU) were duplicated within 6.1 kbp inverted region, which is a unique feature of the genome. The large mtDNA size, however, is explained by the dominance of intronic and intergenic regions (sum 80% of mtDNA sequence). The intergenic DNA stretches harness short (≤200 nt) repetitive, dispersed and overlapping sequence elements in abundance. Long self-splicing introns of types I and II interrupt eleven of the conserved genes (cox1,2,3; cob; nad1,2,4,4L,5; rnl; rns). The introns embrace a total of 57 homing endonucleases with LAGLIDADGD and GYI-YIG core motifs, which makes P. radiata mtDNA to one of the largest known reservoirs of intron-homing endonucleases. The inverted duplication, intergenic stretches, and intronic features are indications of dynamics and genetic flexibility of the mtDNA, not fully recognized to this extent in fungal mitochondrial genomes previously, thus giving new insights for the evolution of organelle genomes in eukaryotes.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Mitochondrial Genome of Phlebia radiata Is the Second Largest (156 kbp) among Fungi and Features Signs of Genome Flexibility and Recent Recombination Events

et al. 2014

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“…Inclusive, se conoce que el estudio del papel de transferencia de genes horizontales en aparición fitopatogénica, podría contribuir a la selección de posibles genes interesantes para su posterior análisis experimental centrado en la adquisición de una mejor comprensión de la aparición de los mecanismos de fitopatógenos y de los estilos de vida de estos hongos, lo que podría conducir al desarrollo de nuevas estrategias de control contra estos microrganismos (Tiburcio et al, 2010). En la actualidad se están realizando estudios del genoma del hongo M. roreri, que permitirá una imagen más completa de su evolución, mejorará el conocimiento de su biología, pudiendo también ayudar en el desarrollo de estrategias para un mejor control (Costa et al, 2012).…”

Section: Control Genéticounclassified

Moniliophthora roreri (Cif y Par) Evans et al. in the crop of cocoa

Mora

Fiallos

2012

Sci. agropecu

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Recibido 02 febrero 2012; aceptado 08 agosto 2012 ResumenMás de un siglo, el cacao (Theobroma cacao L.) en el Ecuador ha sido fuente importante de ingresos para los agricultores y de divisas para el país, llegando a ser uno de los exportadores más grandes a nivel mundial. Posteriormente, perdió paulatinamente ese estatus debido al ataque de enfermedades, entre ellas la moniliasis causada por [Moniliophthora roreri (Cif y Par) Evans et al.]. Esta enfermedad puede causar daños hasta del 80% en la producción. Actualmente no existe mucha información actualizada y científica, sobre su ocurrencia, sintomatología, etiología, epidemiología, ciclo de vida y manejo o estrategias de control de la mencionada enfermedad, por la tanto se realiza esta revisión con estos tópicos importantes, aportando con esto a esta área del conocimiento. Palabras clave: Moniliasis, Theobroma cacao, conidias, manejo integrado. AbstractMore than a century, cacao (Theobroma cacao L.) in Ecuador has been an important source of income for farmers and currency for the country, becoming one of the biggest exporters worldwide. Then, gradually lost that status due to the attack of diseases, including moniliasis caused by [Moniliophthora roreri (Cif and Par) Evans et al.]. It can cause damage of up to 80% in production. Currently there is little scientific date information on its occurrence, symptoms, etiology, epidemiology, life cycle management or control strategies of that disease, by performing this review both these important topics, bringing with it to this area of knowledge.

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Complete mitochondrial genome of the aluminum‐tolerant fungusRhodotorula taiwanensisRS1 and comparative analysis ofBasidiomycotamitochondrial genomes

et al. 2013

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The complete mitochondrial genome of Rhodotorula taiwanensis RS1, an aluminum-tolerant Basidiomycota fungus, was determined and compared with the known mitochondrial genomes of 12 Basidiomycota species. The mitochondrial genome of R. taiwanensis RS1 is a circular DNA molecule of 40,392 bp and encodes the typical 15 mitochondrial proteins, 23 tRNAs, and small and large rRNAs as well as 10 intronic open reading frames. These genes are apparently transcribed in two directions and do not show syntenies in gene order with other investigated Basidiomycota species. The average G+C content (41%) of the mitochondrial genome of R. taiwanensis RS1 is the highest among the Basidiomycota species. Two introns were detected in the sequence of the atp9 gene of R. taiwanensis RS1, but not in that of other Basidiomycota species. Rhodotorula taiwanensis is the first species of the genus Rhodotorula whose full mitochondrial genome has been sequenced; and the data presented here supply valuable information for understanding the evolution of fungal mitochondrial genomes and researching the mechanism of aluminum tolerance in microorganisms.

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The mitochondrial genome of Moniliophthora roreri, the frosty pod rot pathogen of cacao

Cited by 35 publications

References 54 publications

Mitochondrial Genome of Phlebia radiata Is the Second Largest (156 kbp) among Fungi and Features Signs of Genome Flexibility and Recent Recombination Events

Mitochondrial Genome of Phlebia radiata Is the Second Largest (156 kbp) among Fungi and Features Signs of Genome Flexibility and Recent Recombination Events

Moniliophthora roreri (Cif y Par) Evans et al. in the crop of cocoa

Complete mitochondrial genome of the aluminum‐tolerant fungusRhodotorula taiwanensisRS1 and comparative analysis ofBasidiomycotamitochondrial genomes

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