The microbial pH-stable exogenous multienzyme improved growth performance and intestinal morphology of weaned pigs fed a corn–soybean-based diet

Abstract

The present study investigated the effects of dietary supplementation of multienzyme preparation on growth performance, apparent total tract digestibility (ATTD) of nutrients, and gut health of weaned pigs. A total of 240 weaned pigs (initial body weight: 7.3 ± 0.7 kg) were randomly allotted to five treatments on the basis of body weight. The dietary treatments included a corn-soybean meal (SBM)-based diet supplemented with 0 (control), 0.025, 0.050%, 0.075%, or 0.10% multienzyme preparation. The experimental diets were fed in a meal form for two phases (d 0-14, phase I and d 15-28, phase II). Increasing multienzyme supplementation linearly improved overall (d 0-28) average daily gain, gain:feed, and ATTD of dry matter, gross energy, and crude protein. At d 21, pigs fed dietary increasing levels of multienzyme preparation had linearly greater Lactobacillus spp. (ileum and caecum and faeces) and fewer Clostridium spp. (ileum and caecum) and Escherichia coli (ileum and faeces) populations. On d 28, villus height of the jejunum and ileum were linearly increased with dietary increase in multienzyme preparation. In conclusion, this multienzyme has potential to improve the growth performance, ATTD of nutrients, and gut health of weaned pigs fed a corn-SBM-based diet in the absence of antibiotics growth promoters. ARTICLE HISTORY

Effects of Dietary β-Mannanase Supplementation on Growth Performance, Apparent Total Tract Digestibility, Intestinal Integrity, and Immune Responses in Weaning Pigs

“…Previous study conducted with weaning pigs reported that applications of NSP-degrading enzymes such as mixtures of glucanase and xylanase significantly altered the production of SCFA and the profiles of gut-associated microflora in weaning pigs [38]. Similarly, Kim et al [39] reported that the inclusion of multi-enzymes in the weaning diet modulated ileum and cecum microflora by increasing the count of Lactobacillus spp. and decreasing the count of E. coli.…”

Hot melt extruded-based nano zinc as an alternative to the pharmacological dose of ZnO in weanling piglets

“…To evaluate the small intestinal villus height and crypt depth, on d 28, intestinal samples from euthanized pigs (1 male and 1 female) in each pen were collected. For each intestinal sample, three cross-sections were prepared after staining with azure A and eosin using standard paraffin embedding procedures [13]. A total of 10 intact, well-oriented crypt-villus units were selected in triplicate for each intestinal cross-section.…”

Comparative standardized ileal amino acid digestibility and metabolizable energy contents of main feed ingredients for growing pigs when adding dietary β-mannanase

“…The results support the data of Kim et al., (2017) showing that, compared with control diet, the ADG of growing pigs linearly improved by 8.8% in a two-phase feeding regime when β-mannanase supplemented to the diet. Kim et al. (2018b) reported a linear increase in ADG of weaned pigs fed corn-SBM-based feeds formulated with different levels of β-mannanase.…”

“…The concentrations of AA in corn, wheat, and SBM determined in growing pigs was within the range of that were previously reported (NRC, 2012). Several studies showed that NSP has an adverse effect on AA losses (Passos et al., 2015, Cadogan and Choct, 2015, Kim et al., 2018b). Increased AID of AA in diets containing β-mannanase is likely caused by the fact that supplemented β-mannanase decreases the digesta viscosity by hydrolyzing the bonds between mannan units (Shim et al., 2017).…”

“…The importance of the measured GE content in the β-mannanase-treated diet is more likely that the extra energy contents can compromise the other nutrients balance. The main reason for the significant effect of β-mannanase on the digestibility of energy in PKM refers to the enzymatic effects of β-mannanase on cleaving the bonds (Kim et al., 2017, Kim et al., 2018b), while the NSP content in corn and wheat are negligible.…”