The methionase chain reaction: an enzyme-based autocatalytic amplification system for the detection of thiols

Abstract

The methionase chain reaction is developed; thiols are detected at nanomolar concentrations through the autocatalytic reactivation of methionine gamma-lyase.

A comparative life cycle analysis of electromicrobial production systems

“…[1][2][3] Moreover, some products, such as proteins, can only be produced biologically and have wideranging applications including in food production, chemical sensing, and as therapeutics. [4][5][6] Traditional bioprocesses rely on heterotrophic microbes that require exogenous sources of carbon and energy (Fig. 1).…”

Exponential amplification by redox cross-catalysis and unmasking of doubly protected molecular probes

“…20, 22 and 23) and uoride ions. [24][25][26][27] More recently, alternative strategies based on self-propagating thiolate-disulde exchange, 28,29 methionase chain reaction, 30 or photoinduced autocatalysis 31,32 were also reported. However, all these methods suffer from undesirable background reactions, which prevent the achievement of very low analyte concentrations.…”

A comparative life cycle analysis of electromicrobial production systems

“…[1][2][3] Moreover, some products, such as proteins, can only be produced biologically and have wide-ranging applications including in food production, chemical sensing, and as therapeutics. [4][5][6] Traditional bioprocesses rely on heterotrophic microbes that require exogenous sources of carbon and energy (Fig. 1).…”