“…The excess manganese dioxide was filtered, and the solvent from the filtrate was removed on a rotavapor. The residue was dissolved in dry methanol (20 , aromatic C,-H), 8.05 (dd, 1H, J = 0.8,7.6 Hz, aromatic C,-H), 7.95 (bd, lH, J = 8.6 Hz, aromatic C,-H), 7.85 (dt, 1H, J = 0.8,7.5 Hz, aromatic C,-H), 7. 81 (dd, lH, J = 1.3,8.2 Hz, aromatic Cs-H), 7 azine ( 2 b 5 b , respectively). Thus, it was demonstrated that the aliphatic tertiary amine nitrogen underwent oxidation irrespective of whether it was acyclic as in chlorpromazine, cyclic as in the pipermine type phenothiazines fluphenazine, piperidine-type phenothiazine sulforidazine.…”